Chlamydia pneumoniae binds to platelets and triggers P-selectin expression and aggregation: A causal role in cardiovascular disease?

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 23, Issue 9, 2003, Pages 1677-1683

  Kälvegren, Hanna ^a   Majeed, Meytham ^b   Bengtsson, Torbjörn ^b  

^a LINKÖPING UNIVERSITY   (Sweden)

^b NONE

Author keywords

Atherosclerosis; Bacteria cell interaction; LPS; Thrombosis

Indexed keywords

ABCIXIMAB; ARGINYLGLYCYLASPARTYLSERINE; BACTERIUM LIPOPOLYSACCHARIDE; GLYCOPROTEIN IIB; GLYCOPROTEIN IIIA; PADGEM PROTEIN; POLYMYXIN B;

ARTICLE; ATHEROGENESIS; BACTERIAL CELL; BLOOD VESSEL OCCLUSION; CELL INTERACTION; CHLAMYDOPHILA PNEUMONIAE; FLOW CYTOMETRY; HIGH TEMPERATURE; INCUBATION TIME; MEDICAL ASSESSMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN SECRETION; PROTEIN SYNTHESIS INHIBITION; THROMBOCYTE ACTIVATION; THROMBOCYTE ADHESION; THROMBOCYTE AGGREGATION; THROMBOCYTE FUNCTION;

BACTERIAL ADHESION; BLOOD PLATELETS; CARDIOVASCULAR DISEASES; CELL LINE; CHLAMYDIA INFECTIONS; CHLAMYDOPHILA PNEUMONIAE; ESCHERICHIA COLI; HUMANS; LIPOPOLYSACCHARIDES; NEUTROPHILS; P-SELECTIN; PLATELET ACTIVATION; PLATELET AGGREGATION; PLATELET GLYCOPROTEIN GPIB-IX COMPLEX; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; SALMONELLA TYPHIMURIUM; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS;

EID: 0042190484     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.0000084810.52464.D5     Document Type: Article

References (38)

1. Nieminen MS, Mattila K, Valtonen V. Infection and inflammatory risk factors for myocardial infarction. Eur Heart J. 1993;14:12-16.
2. Danesh J, Collins R, Peto R. Chronic infections and coronary heart disease: is there a link? Lancet. 1997;350:430-436.
3. Becker AE, J de Boer O, van der Wal AC. The role of inflammation and infection in coronary heart disease. Annu Rev Med. 2001;52:289-297.
4. Gupta S. Chronic infection in the etiology of atherosclerosis-focus on Chlamydia pneumoniae. Atherosclerosis. 1999;143:1-6.
5. Vainas T, Kurvers HAJM, Mess WH, de Graaf R, Rajaa E, Tordoid JHM, Schurink GH, Bruggeman CA, Kitslaar PJEHM. Chlamydia pneumoniae serology is associated with thrombosis-related but not with plaque related microembolization during carotid endarterectomy. Stroke. 2002;33 1249-1254.
6. Lozinguez O, Arnaud E, Belec L, Nicaud V, Alhenc-Gelas M, Fiessinger JN, Aiach M, Emmerich J. Demonstration of an association between Chlamydia pneumoniae infection and venous thromboembolic disease. Thromb Haemost. 2000;83:887-891.
7. Grayston JT. Chlamydia pneumoniae, strain TWAR pneumoniae. Annu Rev Med. 1992;43:317-323.
8. Saikku P, Leinonen M, Mattila K, Ekman MR, Nieminen MS, Makela PH, Huttunen JK, Valtonen V. Serological evidence of an association of a novel chlamydia, TWAR, with chronic coronary heart disease and acute myocardial infarction. Lancet. 1988;2:983-986.
9. Kuo CC, Gown AM, Benditt EP Grayston JT. Detection of Chlamydia pneumoniae in aortic lesions of atherosclerosis by immunocytochemical staining. Arterioscler Thromb. 1993;13:1501-1504.
10. Gaydos CA, Summersgill JT, Sahney NN, Ramirez JA, Quinn TC. Replication of Chlamydia pneumoniae in vitro in human macrophages, endothelial cells, and aortic artery smooth muscle. Infect Immunol. 1996;64:1614-1620.
11. Klinger MHF. Platelets and inflammation. Anat Embryol. 1997;196:1-11.
12. Marcus AJ. Platelets: their role in hemostasis, thrombosis, and inflammation. In: Gallin JI, Snyderman R, eds. Inflammation: Basic Principles and Clinical Correlates. Philadelphia, Pa: Lippincott Williams & Wilkins; 1999:77-95.
13. Bengtsson T, Zalavary S, Stendahl O, Grenegård M. Release of oxygen metabolites from chemoattractant-stimulated neutrophils is inhibited by resting platelets: role of extracellular adenosine and actin polymerization. Blood. 1996;87:4411-4423.
14. Bengtsson T, Frydén A, Zalavary S, Whiss P, Orselius K, Grenegård M. Platelets enhance neutrophil locomotion: evidence for a role of P-selectin. Scand J Clin Lab Invest. 1999;59:1-11.
15. Zalavary S, Grenegård M, Stendahl O, Bengtsson T. Platelets enhance Fc γ receptor mediated phagocytosis and respiratory burst in neutrophils: the role of purinergic modulation and actin polymerization. J Leukoc Biol. 1996;60:58-68.
16. Gurney D, Gregory L, Andrew B. A reliable plasma marker of platelet activation: does it exist? Am J Hematol. 2002;70:139-44.
17. Burger P, Wagner D. Platelet P-selectin facilitates atherosclerotic lesion development. Blood. 2003;101:2661-2666.
18. Redecke V, Dahoff K, Bohnet S, Braun J, Maass M. Interaction of Chlamydia pneumoniae and human alveolar macrophages: infection and inflammatory response. Am J Respir Cell Mol Biol. 1998;19:721-727.
19. van Kuppeveld FJ, van der Logt JT, Angulo AF, van Zoest MJ, Quint WG, Niesters HG, Galama JM, Melchers WJ. Genus- and species-specific identification of mycoplasmas by 16S rRNA amplification. Appl Environ Microbiol. 1992;58:2606-2615.
20. Clawson CC, White JG. Platelet interaction with bacteria. Am J Pahtol. 1971;65:381-395.
21. Massberg S, Enders G, Leiderer R, Eisenmenger S, Vestweber D, Krombach F, Messmer K. Platelet endothelial cell interactions during ischemia/reperfusion-the role of P-selectin. Blood. 1998;92:507-551.
22. Kupatt C, Wichels R, Horstkotte J, Krombach F, Habazettl H, Boekstegers P. Molecular mechanisms of platelet-mediated leukocyte recruitment during myocardial reperfusion. J Leukoc Biol. 2002;72:455-461.
23. Järemo P. Evidence that Chlamydia pneumoniae affects platelet activity in patients with acute myocardial infarction and ST-segment elevations. Scand J Infect Dis. 2001;33:747-748.
24. Diacovo TG, Roth SJ, Boccola JM, Bainton DF. Springer T. A. Neutrophil rolling, arrest and transmigration across activated surface adherent platelets via sequential action of P-selectin and the beta 2-integrin CD11b/CD18. Blood. 1996;88:146-157.
25. Tsuji T, Nagata K, Kioke J, Todoroki N, Irimura T. Induction of superoxide anion production from monocytes and neutrophils by activated platelets though the P-selectin sialyl Lewis X interaction. J Leukoc Biol. 1994;56:583-587.
26. Bengtsson T, Grenegård M. Leucocyte activation by collagen-stimulated platelets in whole blood. Scand J Clin Lab Invest. 2002;62:451-462.
27. Weyrich AS, Prescott SM, Zimmerman GA. Platelets, endothelial cells, inflammatory chemokines, and restenosis: complex signaling in the vascular play book. Circulation. 2002;106:1433-1435.
28. Hayashida K, Tanaka M, Morita H, Hayashi F, Inada T, Suzuki H, Sakamoto T, Katsuragawa M, Hibino H, Kambara H. Chlamydia pneumoniae seropositivity predicts the risk of restenosis after percutaneous transluminal coronary angioplasty. Heart Vessels. 2002;6:137-145.
29. Gawaz M. Platelets and the Pathophysiology of Coronary Heart Disease. In: Blood Platelets, Physiology, Pathophysiology, Membrane Receptor, Antiplatelet Principles, and Therapy for Atherothrombotic Diseases. Stuttgart, Germany: Georg Thieme Verlag; 2001:97-118.
30. O'Brien L, Kerrigan SW, Kaw G, Hogan M, Penades J, Litt D, Fitzgerald DJ, Foster TJ, Cox D. Multiple mechanisms for the activation of human platelet aggregation by Staphylococcus aureus: roles for the clumping factors ClfA and ClfB, the serine-aspartate repeat protein SdrE and protein A. Mol Microbiol. 2002;44:1033-1044.
31. Rund S, Idner B, Brade H, Holst O. Structural analyses of the lipopolysaccharide from Chlamydia trachomatis serotype L2. J Biol Chem. 1999;274:16819-16824.
32. Ogawa T. Chemical structure of lipid A from Porphyromonas (Bacteroides) gingivalis lipopolysaccharide. FEBS Lett. 1993;32:197-201.
33. Endo Y, Shibazaki M, Nakamura M, Takada H. Contrasting effects of lipopolysaccharides (endotoxins) from oral black-pigmented bacteria and Enterobacteriaceae on platelets, a major source of serotonin, and on histamine-forming enzyme in mice. J Infect Dis. 1997;175:1404-1412.
34. Grabarek J, Timmons S, Hawiger J. Modulation of human platelet protein kinase C by endotoxic lipid A. J Clin Invest. 1988;82:964-971.
35. Kuramitsu HK, Kang IC, Qi M. Interactions of Porphyromonas gingivalis with host cells: implications for cardiovascular diseases. J Periodontol. 2003;74:85-89.
36. Kalayoglu MV, Byrne GI. A Chlamydia pneumoniae component that induces macrophage foam cell formation is chlamydial lipopolysaccharide. Infect Immunol. 1988;66:5067-5072.
37. Chronos N, Vahnian A, Betriu A, Emanuelsson H, Goldberg S, Gulba D, van Hout BA. Use of abciximab in interventional cardiology. Eur Heart J. 1998;19:D31-D39.
38. Cimminiello C, Toschi V. Atherothrombosis: the role of platelets. Eur Heart J Suppl. 1999;1:A8-A13.