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Volumn 20, Issue 4, 2007, Pages 497-507

Skp2 is an independent prognosticator of gallbladder carcinoma among p27Kip1-interacting cell cycle regulators: An immunohistochemical study of 62 cases by tissue microarray

Author keywords

Cell cycle; Gallbladder carcinoma; p27kip1; Proteolysis; Skp2

Indexed keywords

CYCLIN A; CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLIN E; KI 67 ANTIGEN; S PHASE KINASE ASSOCIATED PROTEIN 2;

EID: 33947604769     PISSN: 08933952     EISSN: 15300285     Source Type: Journal    
DOI: 10.1038/modpathol.3800762     Document Type: Article
Times cited : (41)

References (42)
  • 2
    • 3042803779 scopus 로고    scopus 로고
    • Biliary tract neoplasms: Update 2003
    • Malka D, Boige V, Dromain C, et al. Biliary tract neoplasms: update 2003. Curr Opin Oncol 2004;16:364-371.
    • (2004) Curr Opin Oncol , vol.16 , pp. 364-371
    • Malka, D.1    Boige, V.2    Dromain, C.3
  • 3
    • 0026667397 scopus 로고
    • Carcinoma of the gallbladder. Histologic types, stage of disease, grade, and survival rates
    • Henson DE, Albores-Saavedra J, Corle D. Carcinoma of the gallbladder. Histologic types, stage of disease, grade, and survival rates. Cancer 1992;70:1493-1497.
    • (1992) Cancer , vol.70 , pp. 1493-1497
    • Henson, D.E.1    Albores-Saavedra, J.2    Corle, D.3
  • 4
    • 33744951007 scopus 로고    scopus 로고
    • Preneoplastic lesions in gallbladder cancer
    • Roa I, de Aretxabala X, Araya JC, et al. Preneoplastic lesions in gallbladder cancer. J Surg Oncol 2006;93:615-623.
    • (2006) J Surg Oncol , vol.93 , pp. 615-623
    • Roa, I.1    de Aretxabala, X.2    Araya, J.C.3
  • 5
    • 33644972080 scopus 로고    scopus 로고
    • Differential cell cycle-regulatory protein expression in biliary tract adenocarcinoma: Correlation with anatomic site, pathologic variables, and clinical outcome
    • Jarnagin WR, Klimstra DS, Hezel M, et al. Differential cell cycle-regulatory protein expression in biliary tract adenocarcinoma: correlation with anatomic site, pathologic variables, and clinical outcome. J Clin Oncol 2006;24:1152-1160.
    • (2006) J Clin Oncol , vol.24 , pp. 1152-1160
    • Jarnagin, W.R.1    Klimstra, D.S.2    Hezel, M.3
  • 6
    • 0034518430 scopus 로고    scopus 로고
    • K-ras oncogene mutation in cancer and precancerous lesions of the gallbladder
    • Kim SW, Her KH, Jang JY, et al. K-ras oncogene mutation in cancer and precancerous lesions of the gallbladder. J Surg Oncol 2000;75:246-251.
    • (2000) J Surg Oncol , vol.75 , pp. 246-251
    • Kim, S.W.1    Her, K.H.2    Jang, J.Y.3
  • 7
    • 33644875437 scopus 로고    scopus 로고
    • TP53 abnormalities are frequent and early events in the sequential pathogenesis of gallbladder carcinoma
    • Moreno M, Pimentel F, Gazdar AF, et al. TP53 abnormalities are frequent and early events in the sequential pathogenesis of gallbladder carcinoma. Ann Hepatol 2005;4:192-199.
    • (2005) Ann Hepatol , vol.4 , pp. 192-199
    • Moreno, M.1    Pimentel, F.2    Gazdar, A.F.3
  • 8
    • 18344381018 scopus 로고    scopus 로고
    • Cyclin E in normal and neoplastic cell cycles
    • Hwang HC, Clurman BE. Cyclin E in normal and neoplastic cell cycles. Oncogene 2005;24:2776-2786.
    • (2005) Oncogene , vol.24 , pp. 2776-2786
    • Hwang, H.C.1    Clurman, B.E.2
  • 9
    • 0034816198 scopus 로고    scopus 로고
    • Regulation of the cell cycle at the G1-S transition by proteolysis of cyclin E and p27Kip1
    • Nakayama KI, Hatakeyama S, Nakayama K. Regulation of the cell cycle at the G1-S transition by proteolysis of cyclin E and p27Kip1. Biochem Biophys Res Commun 2001;282:853-860.
    • (2001) Biochem Biophys Res Commun , vol.282 , pp. 853-860
    • Nakayama, K.I.1    Hatakeyama, S.2    Nakayama, K.3
  • 10
    • 0344643474 scopus 로고    scopus 로고
    • Cyclin E is a more powerful predictor of breast cancer outcome than proliferation
    • Keyomarsi K, Tucker SL, Bedrosian I. Cyclin E is a more powerful predictor of breast cancer outcome than proliferation. Nat Med 2003;9:152.
    • (2003) Nat Med , vol.9 , pp. 152
    • Keyomarsi, K.1    Tucker, S.L.2    Bedrosian, I.3
  • 11
    • 0037079027 scopus 로고    scopus 로고
    • Cyclin E and survival in patients with breast cancer
    • Keyomarsi K, Tucker SL, Buchholz TA, et al. Cyclin E and survival in patients with breast cancer. N Engl J Med 2002;347:1566-1575.
    • (2002) N Engl J Med , vol.347 , pp. 1566-1575
    • Keyomarsi, K.1    Tucker, S.L.2    Buchholz, T.A.3
  • 12
    • 0033968335 scopus 로고    scopus 로고
    • Cyclin E expression, a potential prognostic marker for nonsmall cell lung cancers
    • Mishina T, Dosaka-Akita H, Hommura F, et al. Cyclin E expression, a potential prognostic marker for nonsmall cell lung cancers. Clin Cancer Res 2000;6:11-16.
    • (2000) Clin Cancer Res , vol.6 , pp. 11-16
    • Mishina, T.1    Dosaka-Akita, H.2    Hommura, F.3
  • 13
    • 0031048716 scopus 로고    scopus 로고
    • Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients
    • Porter PL, Malone KE, Heagerty PJ, et al. Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients. Nat Med 1997;3:222-225.
    • (1997) Nat Med , vol.3 , pp. 222-225
    • Porter, P.L.1    Malone, K.E.2    Heagerty, P.J.3
  • 14
    • 0034791332 scopus 로고    scopus 로고
    • Implication of malignancy and prognosis of p27(kip1), Cyclin E, and Cdk2 expression in epithelial ovarian tumors
    • Sui L, Dong Y, Ohno M, et al. Implication of malignancy and prognosis of p27(kip1), Cyclin E, and Cdk2 expression in epithelial ovarian tumors. Gynecol Oncol 2001;83:56-63.
    • (2001) Gynecol Oncol , vol.83 , pp. 56-63
    • Sui, L.1    Dong, Y.2    Ohno, M.3
  • 15
    • 0041319434 scopus 로고    scopus 로고
    • E- and A-type cyclins as markers for cancer diagnosis and prognosis
    • Yasmeen A, Berdel WE, Serve H, et al. E- and A-type cyclins as markers for cancer diagnosis and prognosis. Expert Rev Mol Diagn 2003;3:617-633.
    • (2003) Expert Rev Mol Diagn , vol.3 , pp. 617-633
    • Yasmeen, A.1    Berdel, W.E.2    Serve, H.3
  • 16
    • 0036692835 scopus 로고    scopus 로고
    • Cyclin A in cell cycle control and cancer
    • Yam CH, Fung TK, Poon RY. Cyclin A in cell cycle control and cancer. Cell Mol Life Sci 2002;59:1317-1326.
    • (2002) Cell Mol Life Sci , vol.59 , pp. 1317-1326
    • Yam, C.H.1    Fung, T.K.2    Poon, R.Y.3
  • 17
    • 0033564486 scopus 로고    scopus 로고
    • Expression of cyclin A in soft tissue sarcomas correlates with tumor aggressiveness
    • Huuhtanen RL, Blomqvist CP, Bohling TO, et al. Expression of cyclin A in soft tissue sarcomas correlates with tumor aggressiveness. Cancer Res 1999;59:2885-2890.
    • (1999) Cancer Res , vol.59 , pp. 2885-2890
    • Huuhtanen, R.L.1    Blomqvist, C.P.2    Bohling, T.O.3
  • 18
    • 0036801653 scopus 로고    scopus 로고
    • Cyclin A correlates with carcinogenesis and metastasis, and p27(kip1) correlates with lymphatic invasion, in colorectal neoplasms
    • Li JQ, Miki H, Wu F, et al. Cyclin A correlates with carcinogenesis and metastasis, and p27(kip1) correlates with lymphatic invasion, in colorectal neoplasms. Hum Pathol 2002;33:1006-1015.
    • (2002) Hum Pathol , vol.33 , pp. 1006-1015
    • Li, J.Q.1    Miki, H.2    Wu, F.3
  • 19
    • 0037207969 scopus 로고    scopus 로고
    • Low p27Kip1 expression is an independent prognostic factor in gallbladder carcinoma
    • Filipits M, Puhalla H, Wrba F. Low p27Kip1 expression is an independent prognostic factor in gallbladder carcinoma. Anticancer Res 2003;23:675-679.
    • (2003) Anticancer Res , vol.23 , pp. 675-679
    • Filipits, M.1    Puhalla, H.2    Wrba, F.3
  • 20
    • 17544366706 scopus 로고    scopus 로고
    • p27(Kip1) expression in normal epithelia, precancerous lesions, and carcinomas of the gallbladder: Association with cancer progression and prognosis
    • Hui AM, Li X, Shi YZ, et al. p27(Kip1) expression in normal epithelia, precancerous lesions, and carcinomas of the gallbladder: association with cancer progression and prognosis. Hepatology 2000;31:1068-1072.
    • (2000) Hepatology , vol.31 , pp. 1068-1072
    • Hui, A.M.1    Li, X.2    Shi, Y.Z.3
  • 21
    • 0035942224 scopus 로고    scopus 로고
    • Skp2 is oncogenic and overexpressed in human cancers
    • Gstaiger M, Jordan R, Lim M, et al. Skp2 is oncogenic and overexpressed in human cancers. Proc Natl Acad Sci USA 2001;98:5043-5048.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 5043-5048
    • Gstaiger, M.1    Jordan, R.2    Lim, M.3
  • 22
    • 31544465982 scopus 로고    scopus 로고
    • Skp2 overexpression is highly representative of intrinsic biological aggressiveness and independently associated with poor prognosis in primary localized myxofibrosarcomas
    • Huang HY, Kang HY, Li CF, et al. Skp2 overexpression is highly representative of intrinsic biological aggressiveness and independently associated with poor prognosis in primary localized myxofibrosarcomas. Clin Cancer Res 2006;12:487-498.
    • (2006) Clin Cancer Res , vol.12 , pp. 487-498
    • Huang, H.Y.1    Kang, H.Y.2    Li, C.F.3
  • 23
    • 17044370346 scopus 로고    scopus 로고
    • Regulation of the cell cycle by SCF-type ubiquitin ligases
    • Nakayama KI, Nakayama K. Regulation of the cell cycle by SCF-type ubiquitin ligases. Semin Cell Dev Biol 2005;16:323-333.
    • (2005) Semin Cell Dev Biol , vol.16 , pp. 323-333
    • Nakayama, K.I.1    Nakayama, K.2
  • 24
    • 0036733716 scopus 로고    scopus 로고
    • Oncogenic role of the ubiquitin ligase subunit Skp2 in human breast cancer
    • Signoretti S, Di Marcotullio L, Richardson A, et al. Oncogenic role of the ubiquitin ligase subunit Skp2 in human breast cancer. J Clin Invest 2002;110:633-641.
    • (2002) J Clin Invest , vol.110 , pp. 633-641
    • Signoretti, S.1    Di Marcotullio, L.2    Richardson, A.3
  • 25
    • 0033174070 scopus 로고    scopus 로고
    • p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells
    • Sutterluty H, Chatelain E, Marti A, et al. p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells. Nat Cell Biol 1999;1:207-214.
    • (1999) Nat Cell Biol , vol.1 , pp. 207-214
    • Sutterluty, H.1    Chatelain, E.2    Marti, A.3
  • 26
    • 0035810976 scopus 로고    scopus 로고
    • Protein destruction: Adapting roles for Cks proteins
    • Harper JW. Protein destruction: adapting roles for Cks proteins. Curr Biol 2001;11:R431-435.
    • (2001) Curr Biol , vol.11
    • Harper, J.W.1
  • 27
    • 9644253021 scopus 로고    scopus 로고
    • Role of Cks1 overexpression in oral squamous cell carcinomas: Cooperation with Skp2 in promoting p27 degradation
    • Kitajima S, Kudo Y, Ogawa I, et al. Role of Cks1 overexpression in oral squamous cell carcinomas: cooperation with Skp2 in promoting p27 degradation. Am J Pathol 2004;165:2147-2155.
    • (2004) Am J Pathol , vol.165 , pp. 2147-2155
    • Kitajima, S.1    Kudo, Y.2    Ogawa, I.3
  • 28
    • 0344198099 scopus 로고    scopus 로고
    • Cyclindependent kinase 1 gene expression is associated with poor prognosis in gastric carcinoma
    • Masuda TA, Inoue H, Nishida K, et al. Cyclindependent kinase 1 gene expression is associated with poor prognosis in gastric carcinoma. Clin Cancer Res 2003;9:5693-5698.
    • (2003) Clin Cancer Res , vol.9 , pp. 5693-5698
    • Masuda, T.A.1    Inoue, H.2    Nishida, K.3
  • 29
    • 15744382959 scopus 로고    scopus 로고
    • The prognostic impact of the ubiquitin ligase subunits Skp2 and Cks1 in colorectal carcinoma
    • Shapira M, Ben-Izhak O, Linn S, et al. The prognostic impact of the ubiquitin ligase subunits Skp2 and Cks1 in colorectal carcinoma. Cancer 2005;103:1336-1346.
    • (2005) Cancer , vol.103 , pp. 1336-1346
    • Shapira, M.1    Ben-Izhak, O.2    Linn, S.3
  • 30
    • 4444245737 scopus 로고    scopus 로고
    • Expression of p27 and its ubiquitin ligase subunit Skp2 in upper urinary tract transitional cell carcinoma
    • Langner C, von Wasielewski R, Ratschek M, et al. Expression of p27 and its ubiquitin ligase subunit Skp2 in upper urinary tract transitional cell carcinoma. Urology 2004;64:611-616.
    • (2004) Urology , vol.64 , pp. 611-616
    • Langner, C.1    von Wasielewski, R.2    Ratschek, M.3
  • 31
    • 0037108299 scopus 로고    scopus 로고
    • Expression of Skp2, a p27(Kip1) ubiquitin ligase, in malignant lymphoma: Correlation with p27(Kip1) and proliferation index
    • Lim MS, Adamson A, Lin Z, et al. Expression of Skp2, a p27(Kip1) ubiquitin ligase, in malignant lymphoma: correlation with p27(Kip1) and proliferation index. Blood 2002;100:2950-2956.
    • (2002) Blood , vol.100 , pp. 2950-2956
    • Lim, M.S.1    Adamson, A.2    Lin, Z.3
  • 32
    • 33947609469 scopus 로고    scopus 로고
    • Greene FL PD, Fleming ID, Fritz AG, et al. Gallbladder Carcinoma, 6th edn. Springer: New York, NY, 2002;139-144.
    • Greene FL PD, Fleming ID, Fritz AG, et al. Gallbladder Carcinoma, 6th edn. Springer: New York, NY, 2002;139-144.
  • 33
    • 0038189900 scopus 로고    scopus 로고
    • Therapeutic anti-cancer targets upstream of the proteasome
    • Nalepa G, Wade Harper J. Therapeutic anti-cancer targets upstream of the proteasome. Cancer Treat Rev 2003;29(Suppl 1):49-57.
    • (2003) Cancer Treat Rev , vol.29 , Issue.SUPPL. 1 , pp. 49-57
    • Nalepa, G.1    Wade Harper, J.2
  • 34
    • 0036650462 scopus 로고    scopus 로고
    • Inadequate formalin fixation decreases reliability of p27 immunohistochemical staining: Probing optimal fixation time using high-density tissue microarrays
    • De Marzo AM, Fedor HH, Gage WR, et al. Inadequate formalin fixation decreases reliability of p27 immunohistochemical staining: probing optimal fixation time using high-density tissue microarrays. Hum Pathol 2002;33:756-760.
    • (2002) Hum Pathol , vol.33 , pp. 756-760
    • De Marzo, A.M.1    Fedor, H.H.2    Gage, W.R.3
  • 35
    • 11844306647 scopus 로고    scopus 로고
    • Skp2 overexpression is a p27Kip1-independent predictor of poor prognosis in patients with biliary tract cancers
    • Sanada T, Yokoi S, Arii S, et al. Skp2 overexpression is a p27Kip1-independent predictor of poor prognosis in patients with biliary tract cancers. Cancer Sci 2004;95:969-976.
    • (2004) Cancer Sci , vol.95 , pp. 969-976
    • Sanada, T.1    Yokoi, S.2    Arii, S.3
  • 36
    • 0035098524 scopus 로고    scopus 로고
    • JAB1/CSN5 and the COP9 signalosome. A complex situation
    • Chamovitz DA, Segal D. JAB1/CSN5 and the COP9 signalosome. A complex situation. EMBO Rep 2001;2:96-101.
    • (2001) EMBO Rep , vol.2 , pp. 96-101
    • Chamovitz, D.A.1    Segal, D.2
  • 37
    • 24044555556 scopus 로고    scopus 로고
    • Molecular dissection of the interaction between p27 and Kip1 ubiquitylation-promoting complex, the ubiquitin ligase that regulates proteolysis of p27 in G1 phase
    • Kotoshiba S, Kamura T, Hara T, et al. Molecular dissection of the interaction between p27 and Kip1 ubiquitylation-promoting complex, the ubiquitin ligase that regulates proteolysis of p27 in G1 phase. J Biol Chem 2005;280:17694-17700.
    • (2005) J Biol Chem , vol.280 , pp. 17694-17700
    • Kotoshiba, S.1    Kamura, T.2    Hara, T.3
  • 38
    • 33644875101 scopus 로고    scopus 로고
    • The expression of the ubiquitin ligase subunit Cks1 in human breast cancer
    • Slotky M, Shapira M, Ben-Izhak O, et al. The expression of the ubiquitin ligase subunit Cks1 in human breast cancer. Breast Cancer Res 2005;7:R737-R744.
    • (2005) Breast Cancer Res , vol.7
    • Slotky, M.1    Shapira, M.2    Ben-Izhak, O.3
  • 39
    • 29244455863 scopus 로고    scopus 로고
    • Amplification and overexpression of CKS1B at chromosome band 1q21 is associated with reduced levels of p27Kip1 and an aggressive clinical course in multiple myeloma
    • Shaughnessy J. Amplification and overexpression of CKS1B at chromosome band 1q21 is associated with reduced levels of p27Kip1 and an aggressive clinical course in multiple myeloma. Hematology 2005;10(Suppl 1):117-126.
    • (2005) Hematology , vol.10 , Issue.SUPPL. 1 , pp. 117-126
    • Shaughnessy, J.1
  • 40
    • 0032622214 scopus 로고    scopus 로고
    • Cyclin E overexpression in human gallbladder carcinomas
    • Eguchi N, Fujii K, Tsuchida A, et al. Cyclin E overexpression in human gallbladder carcinomas. Oncol Rep 1999;6:93-96.
    • (1999) Oncol Rep , vol.6 , pp. 93-96
    • Eguchi, N.1    Fujii, K.2    Tsuchida, A.3
  • 41
    • 1542751717 scopus 로고    scopus 로고
    • Cyclin E and its low molecular weight forms in human cancer and as targets for cancer therapy
    • Akli S, Keyomarsi K. Cyclin E and its low molecular weight forms in human cancer and as targets for cancer therapy. Cancer Biol Ther 2003;2:S38-47.
    • (2003) Cancer Biol Ther , vol.2
    • Akli, S.1    Keyomarsi, K.2
  • 42
    • 26444480631 scopus 로고    scopus 로고
    • Mechanisms of tumor suppression by the SCF(Fbw7)
    • Minella AC, Clurman BE. Mechanisms of tumor suppression by the SCF(Fbw7). Cell Cycle 2005;4:1356-1359.
    • (2005) Cell Cycle , vol.4 , pp. 1356-1359
    • Minella, A.C.1    Clurman, B.E.2


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