Lack of changes in the PI3K/AKT survival pathway in the spinal cord motor neurons of a mouse model of familial amyotrophic lateral sclerosis

Molecular and Cellular Neuroscience

Volumn 34, Issue 4, 2007, Pages 592-602

  Peviani, M ^a   Cheroni, C ^a   Troglio, F ^b   Quarto, M ^c   Pelicci, G ^b   Bendotti, C ^a,d  

^a MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^b EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

^c FIRC INSTITUTE OF MOLECULAR ONCOLOGY   (Italy)

^d IRCCS   (Italy)

Author keywords

Akt; Amyotrophic lateral sclerosis; Motor neuron; N Shc; Signaling pathways; SOD1

Indexed keywords

PHOSPHATIDYL INOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL KINASE; PROTEIN KINASE B; UNCLASSIFIED DRUG;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CONTROLLED STUDY; DISEASE COURSE; DISEASE MODEL; ENZYME MECHANISM; ENZYME PHOSPHORYLATION; ENZYME REPRESSION; FEMALE; IMMUNOREACTIVITY; MALE; MOTONEURON; MOTOR DYSFUNCTION; MOUSE; NERVE CELL DEGENERATION; NONHUMAN; PRIORITY JOURNAL; SPINAL CORD NERVE CELL; SPINAL CORD VENTRAL HORN;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; BLOTTING, WESTERN; CELL SURVIVAL; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; IMMUNOHISTOCHEMISTRY; MICE; MICE, TRANSGENIC; MICROSCOPY, CONFOCAL; MOTOR NEURONS; NERVE DEGENERATION; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; SPINAL CORD; SUPEROXIDE DISMUTASE;

MUS;

EID: 33947597027     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mcn.2007.01.003     Document Type: Article

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