Two new disposable bioreactors for plant cell culture: The wave and undertow bioreactor and the slug bubble bioreactor

Biotechnology and Bioengineering

Volumn 96, Issue 5, 2007, Pages 914-923

  Terrier, Bénédicte ^a   Courtois, Didier ^a   Hénault, Nicolas ^a   Cuvier, Arnaud ^a   Bastin, Maryse ^a   Aknin, Aziz ^a   Dubreuil, Julien ^a   Pétiard, Vincent ^a  

^a NESTLÉ RESEARCH CENTER   (Switzerland)

Author keywords

Cell culture; Disposable bioreactor; Glycine max; Nicotiana tabacum; Secondary metabolites; Slug bubble

Indexed keywords

METABOLITES; PLANT CELL CULTURE; SLAGS; STAINLESS STEEL;

DISPOSABLE BIOREACTORS; GLYCINE MAX; NICOTIANA TABACUM; SECONDARY METABOLITES; SLUG BUBBLE BIOREACTORS;

BIOREACTORS;

ISOFLAVONE DERIVATIVE; STAINLESS STEEL;

ARTICLE; BIOREACTOR; CELL DENSITY; CLEANING; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; DISPOSABLE EQUIPMENT; EQUIPMENT DESIGN; GROWTH RATE; INSTRUMENT STERILIZATION; NONHUMAN; PLANT CELL CULTURE; SHEAR RATE; SOYBEAN; TOBACCO; VOLUMETRY;

GLYCINE MAX; NICOTIANA TABACUM;

EID: 33947589940     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.21187     Document Type: Article

References (46)

1. Alfermann AW, Petersen M. 1995. Natural product formation by plant cell biotechnology. Plant Cell Tiss Org Cult 43:199-205.
2. Bentebibel S, Moyano E, Palazon J, Cusido RM, Bonfill M, Eibl R, Pinol MT. 2005. Effect of immobilization by entrapment in alginate and scale-up on paclitaxel and baccatin III production in cell suspension cultures of Taxus baccata. Biotechnol Bioeng 89(6):647-653.
3. Campos JBLM, Guedes de Carvalho JRF. 1988. An experimental study of the wake of gas slugs rising in liquids. J Fluid Mech 196:27-37.
4. Cherry JJ, Hulle CT. 1992. Cell death in the thin film of rising bubbles. Biotechnol Prog 8:11-18.
5. Choi SM, Lee O, Kwon S, Kwak SS, Yu D, Lee HS. 2003. High expression of a human lactoferrin in transgenic tobacco cell cultures. Biotechnol Lett 25:213-218.
6. Courtois D, Yvernel Y, Florin B, Pétiard V. 1988. Conversion of tryptamine to serotonin by cell suspension cultures of Peganum harmala. Phytochemistry 27(10):3137-3142.
7. Curtis WR. 1999. Achieving economic feasibility for moderate-value food and flavor additives: A perspective on productivity and proposal for production technology cost reduction. In: Fu TJ, Singh G, Curtis WR, editors. Plant cell culture for the production of food ingredients. New-York: Kluwer Acad./Plenum. p 225-236.
8. Davies RM, Taylor G. 1950. The mechanics of large bubbles rising trough extended liquids in tubes. Proc Royal Soc London Ser A 200: 375-390.
9. Doran PM. 1993. Design of bioreactors for plant cell and organs. Adv Biochem Eng Biotechnol 48:117-168.
10. Doran PM. 2000. Foreign proteins production in plant tissue cultures. Curr Opin Biotechnol 11:199-204.
11. Eibl R, Eibl D. 2006. Design and use of the wave bioreactor for plant cell culture. In: Gupta D, Ibaraki Y, editors. Plant tissue culture engineering. Dordrecht, Springer. p 203-227.
12. Federici E, Touche A, Choquart S, Avanti O, Fay L, Offord E, Courtois D. 2003. High isoflavone content and estrogenic activity of 25 year-old Glycine max tissue cultures. Phytochemistry 64(3):717-724.
13. Fu TJ, Singh G, Curtis WR. 1999. Plant cell and tissue culture for the production of food ingredients. New-York: Kluwer Acad./Plenum. 290 p.
14. Gamborg OL, Miller RA, Ojima K. 1968. Nutrient requirements of suspension cultures of soybean root cells. Exp Cell Res 50:151-158.
15. Gao J, Hooker BS, Anderson DB. 2004. Expression of functional human coagulation factor XIII A-domain in plant cell suspensions and whole plants. Prot Exp Purif 37:89-96.
16. Girard LS, Bastin M, Courtois D. 2004. Expression of the human milk protein sCD14 in tobacco plant cell culture. Plant Cell Tiss Org Cult 78:253-260.
17. Handa-Corrigan A, Emery AN, Spier RE 1989. Effect of gas-liquid interfaces on the growth of suspended mammalian cells: Mechanisms of cell damage by bubbles. Enz Microb Technol 11:230-235.
18. Hellwig S, Drossard J, Twyman RM, Fischer R. 2004. Plant cell cultures for the production of recombinant proteins. Nat Biotechnol 22(11):1415-1422.
19. Hibino K, Ushiyama K. 1999. Commercial production of ginseng by plant tissue culture technology. In: Fu TJ, Singh G, Curtis WR, editors. Plant cell and tissue culture for the production of food ingredients. New York: Kluwer Acad./Plenum. p 215-224.
20. Hsiao TY, Bacani FT, Carvahlo EB, Curtis WR. 1999. Development of a low capital investment reactor system: Application for plant cell suspension culture. Biotechnol Prog 15(1):114-122.
21. James MR, Lane SJ, Chouet B, Gilbert JS. 2004. Pressure changes associated with the ascent and bursting of gas slugs in liquid-filled vertical and inclined conduits. J Volcan Geo Res 129(1-3):61-82.
22. Kantarci N, Borak F, Ulgen KO, 2005. Bubble column reactors. Process Biochem 40:2263-2283.
23. Kurz WGW, 1971. A chemostat for growing higher plant cells in single cell suspension cultures. Exp Cell Res 64(2):476-479.
24. Matsubara K, Fujita S. 1991. Production of berberine. In: Komamine A, Misawa M, Di Cosmo F, editors. Plant cell culture in Japan. Tokyo: CMC Co. Ltd. p 72-78.
25. McDonald KA, Hong LM, Trombly DM, Xie Q, Jackman AP. 2005. Production of human alpha-1-antitrypsin from transgenic rice cell culture in a membrane bioreactor. Biotechnol Prog 21(3):728-734.
26. Misawa M. 1994. Plant tissue culture: An alternative for production of useful metabolites. FAO Agricultural Services Bulletin No108. Ed. Food and Agriculture Organization of the United Nations, Rome. 95 p.
27. Mulabagal V, Tsay H. 2004. Plant cell cultures - an alternative and efficient source for the production of biologically important secondary metabolites. Int J Appl Sci Eng 2(1):29-48.
28. Murashige R, Skoog F. 1962. A revised medium for rapid growth and bioassays with tobacco tissue cultures. Physiol Plant 15:473-497.
29. Nagata T. 2004. When I encountered tobacco BY-2 cells! In: Nagata T, Hasezawa S, Inzé D, editors. Tobacco BY-2 cells. Biotechnology in agriculture and forestry, vol. 53. Berlin: Springer-Verlag. p 1-5.
30. Nicklin DJ, Wilkes JO, Davidson JF. 1962. Two-phase flow in vertical tubes. Trans Inst Chem Eng 40:61-68.
31. Palazon J, Mallol A, Eibl R, Lettenbauer C, Cusido RM, Pinol MT. 2003. Growth and ginsenoside production in hairy root cultures of Panax ginseng using a novel bioreactor. Planta Med 69(4):344-349.
32. Sajc L, Grubisic D, Vunjak-Novakovic G. 2000. Bioreactors for plant engineering: An outlook for further research. Biochem Eng J 4:89-99.
33. Schmale K, Rademacher T, Fischer R, Hellwig S. 2006. Towards industrial usefulness - cryo-cell-banking of transgenic BY-2 cell cultures. J Biotechnol 124:302-311
34. Singh V. 1999. Disposable bioreactor for cell culture using wave-induced agitation. Cytotechnology 30:149-158.
35. Soderquist RG, Lee JM. 2005. Enhanced production of recombinant proteins from plant cells by the application of osmotic stress and protein stabilization. Plant Cell Rep 24(2):127-132.
36. Sorrentino A, Schilberg S, Fischer R, Rao R, Porta R, Mariniello L. 2005. Recombinant human tissue transglutaminase produced in tobacco suspension cell cultures is active and recognizes autoantibodies in the serum of coeliac patients. Int J Biochem Cell Biol 37:852-861.
37. Sousa RG, Riethmuller ML, Pinto AMFR, Campos JBLM. 2005. Flow around individual Taylor bubbles rising in stagnant CMC solutions: PIV measurements. Chem Eng Sci 60:1589-1873.
38. Stafford AM. 2002. Plant cell cultures as a source of bioactive small molecules. Cur Opinion Drug Discov 5(2):296-303.
39. Stockigt J, Obitz P, Falkenhagen H, Lutterbach R, Endreβ S. 1995. Natural products and enzymes from plant cell cultures. Plant Cell Tiss Org Cult 43:97-109.
40. Takahasi S, Fujita Y. 1991. Production of shikonin. In: Komamine A, Misawa M, Di-Cosmo F, editors. Plant cell culture in Japan. Tokyo: CMC Co. Ltd, p 72-78.
41. Venkat K. 1998. Paclitaxel production through plant cell culture: An exciting approach to harnessing biodiversity. Pure Appl Chem 70(11):2127-2128.
42. Verdelhan des Molles D, Gomord V, Bastin M, Faye L, Courtois D. 1999. Expression of a carrot invertase gene in tobacco suspension cells cultivated in batch and continuous culture conditions. J Biosci Bioeng 87:302-306.
43. Wu J, Goosen MFA. 1995. Evaluation of the killing volume of gas bubbles in sparged animal cell culture bioreactors. Enzyme Microb Technol 17(12):1036-1042.
44. Wu J, Zhong JJ. 1999. Production of ginseng and its bioactive components in plant cell culture: Current technological and applied aspects. J Biotechnol 68:89-99.
45. Yoshioka T, Fujita Y. 1988: Economic aspects of plant cell biotechnology. In: Pais MS, Mavituna F, Novais JM, editors. Plant cell biotechnology. Berlin: Springer Verlag. p 475-482.
46. Zhong JJ. 2001. Biochemical engineering of the production of plant-specific secondary metabolites by cell suspension cultures. In: Scheper T, editor. Advances in biochemical engineering/biotechnology, vol. 72, Berlin: Springer-Verlag. p 1-26.