Effects of immobilization by entrapment in alginate and scale-up on paclitaxel and baccatin III production in cell suspension cultures of Taxus baccata

Biotechnology and Bioengineering

Volumn 89, Issue 6, 2005, Pages 647-655

  Bentebibel, Salima ^a   Moyano, Elisabet ^b   Palazón, Javier ^a   Cusidó, Rosa M ^a   Bonfill, Mercedes ^a   Eibl, Regine ^c   Piñol, M Teresa ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b UNIVERSITAT POMPEU FABRA   (Spain)

^c Hochschule Aädenswill   (Switzerland)

Author keywords

Baccatin III; Immobilized cells; Paclitaxel; Scale up; Taxus baccata

Indexed keywords

BIOREACTORS; BIOSYNTHESIS; CELL CULTURE;

BACCATIN III-PRODUCING CELLS; PACLITAXEL III-PRODUCING CELLS; STIRRED BIOREACTORS; TAXUS BACCATA;

CELL IMMOBILIZATION;

ALGINIC ACID; BACCATIN III; CALCIUM ALGINATE; PACLITAXEL; TAXANE DERIVATIVE;

AIRLIFT REACTOR; ARTICLE; BIOREACTOR; BIOSYNTHESIS; CELL CULTURE; CELL GROWTH; CELL SUSPENSION; DRUG SYNTHESIS; IMMOBILIZATION; SCALE UP; STIRRED REACTOR; TAXUS BACCATA;

ALGINATES; ALKALOIDS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BIOMASS; BIOREACTORS; BIOTECHNOLOGY; CELLS, CULTURED; GLUCURONIC ACID; HEXURONIC ACIDS; PACLITAXEL; TAXOIDS; TAXUS;

TAXUS; TAXUS BACCATA;

EID: 16344367973     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/bit.20321     Document Type: Article

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