Effectiveness of hyperopic defocus, minimal defocus, or myopic defocus in competition with a myopiagenic stimulus in tree shrew eyes

Investigative Ophthalmology and Visual Science

Volumn 47, Issue 11, 2006, Pages 4687-4699

  Norton, Thomas T ^a   Siegwart Jr , John T ^a   Amedo, Angela O ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACCOMMODATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE MODEL; HYPEROPIC DEFOCUS; LENS IMPLANT; LENS POWER; MINIMAL DEFOCUS; MYOPIA; MYOPIC DEFOCUS; NONHUMAN; PRIORITY JOURNAL; REFRACTION INDEX; SCANDENTIA; STIMULUS RESPONSE; VISUAL STIMULATION; VITREOUS BODY; ANIMAL; BINOCULAR VISION; EYE; EYE REFRACTION; GROWTH, DEVELOPMENT AND AGING; HYPERMETROPIA; NEWBORN; PATHOPHYSIOLOGY; PHYSIOLOGY; RETINOSCOPY; SENSORY DEPRIVATION; SPECTACLES;

ANIMALS; ANIMALS, NEWBORN; DISEASE MODELS, ANIMAL; EYE; EYEGLASSES; HYPEROPIA; MYOPIA; REFRACTION, OCULAR; RETINOSCOPY; SENSORY DEPRIVATION; TUPAIA; VISION, BINOCULAR;

EID: 33947589569     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.05-1369     Document Type: Article

References (48)

1. Norton TT, McBrien NA. Normal development of refractive state and ocular component dimensions in the tree shrew (Tupaia belangeri). Vision Res. 1992;32:833-842.
2. Pickett-Seltner RL, Sivak JG, Paternak JJ. Experimentally induced myopia in chicks: morphometric and biochemical analysis during the first 14 days after hatching. Vision Res. 1988;28:323-328.
3. Smith EL III, Hung LF. The role of optical defocus in regulating refractive development in infant monkeys. Vision Res. 1999;39:1415-1435.
4. Bradley DV, Fernandes A, Lynn M, Tigges M, Boothe RG. Emmetropization in the rhesus monkey (Macaca mulatta): birth to young adulthood. Invest Ophthalmol Vis Sci 1999;40:214-229.
5. Cook RC, Glasscock RE. Refractive and ocular findings in the newborn. Am J Ophthalmol. 1951;34:1407-1413.
6. Mayer DL, Hansen RM, Moore BD, Kim S, Fulton AB. Cycloplegic refractions in healthy children aged 1 through 48 months. Arch Ophthalmol. 2001;119:1625-1628.
7. Mutti DO, Mitchell GL, Jones LA, et al. Axial growth and changes in lenticular and corneal power during emmetropization in infants. Invest Ophthalmol Vis Sci. 2005;46:3074-3080.
8. Schaeffel F, Glasser A, Howland HC. Accommodation, refractive error and eye growth in chickens. Vision Res. 1988;28:639-657.
9. Irving EL, Callender MG, Sivak JG. Inducing myopia, hyperopia, and astigmatism in chicks. Optom Vis Sci. 1991;68:364-368.
10. Siegwart JT Jr, Norton TT. Regulation of the mechanical properties of tree shrew sclera by the visual environment. Vision Res. 1999;39:387-407.
11. Siegwart JT Jr, Norton TT. The time course of changes in mRNA levels in tree shrew sclera during induced myopia and recovery. Invest Ophthalmol Vis Sci. 2002;43:2067-2075.
12. Wallman J, Winawer J. Homeostasis of eye growth and the question of myopia. Neuron. 2004;43:447-468.
13. Schaeffel F, Diether S. The growing eye: an autofocus system that works on very poor images. Vision Res. 1999;39:1585-1589.
14. Winawer J, Zhu X, Choi J, Wallman J. Ocular compensation for alternating myopic and hyperopic defocus. Vision Res. 2005;45:1667-1677.
15. Oishi T, Lauber JK, Vriend J. Experimental myopia and glaucoma in chicks. Zoological Science. 1987;4:455-464.
16. Lauber JK. Review: avian models for experimental myopia. J Ocular Pharmacol. 1991;7:259-276.
17. Stone RA, Lin T, Desai D, Capehart C. Photoperiod, early post-natal eye growth, and visual deprivation. Vision Res. 1995;35:1195-1202.
18. Norton TT, Amedo AO, Siegwart JT Jr. Darkness causes myopia in visually experienced tree shrews. Invest Ophthalmol Vis Sci. 2006;47:4700-4707.
19. Schmid KL, Wildsoet CF. Effects on the compensatory responses to positive and negative lenses of intermittent lens wear and ciliary nerve section in chicks. Vision Res. 1996;36:1023-1036.
20. Shaikh AW, Siegwart JT, Norton TT. Effect of interrupted lens wear on compensation for a minus lens in tree shrews. Optom Vis Sci. 1999;76:308-315.
21. Smith EL III, Hung LF, Kee CS, Qiao Y. Effects of brief periods of unrestricted vision on the development of form-deprivation myopia in monkeys. Invest Ophthalmol Vis Sci. 2002;43:291-299.
22. Norton TT, Siegwart JJT. Lens substitution during compensation for a minus lens: a paradigm for assessing visual stimuli that regulate axial elongation and refractive state. In: Lin LLK, Shin Y-F, Hung P-T, eds. Myopia Updates II, Proceedings of the 7th International Conference on Myopia. Tokyo: Springer-Verlag; 2000:119-122.
23. Zhu X, Winawer JA, Wallman J. Potency of myopic defocus in spectacle lens compensation. Invest Ophthalmol Vis Sci. 2003;44:2818-2827.
24. Siegwart JT, Norton TT. Goggles for controlling the visual environment of small animals. Lab Animal Sci. 1994;44:292-294.
25. Bobier WR, Braddick OJ. Eccentric photorefraction: optical analysis and empirical measures. Am J Optom Physiol Opt. 1985;62:614-620.
26. Howland HC, Braddick O, Atkinson J, Howland B. Optics of photorefraction: orthogonal and isotropic methods. J Opt Soc Am. 1983;73:1701-1708.
27. Braddick O, Atkinson J, French J, Howland HC. A photorefractive study of infant accommodation. Vision Res. 1979;19:1319-1330.
28. Amedo AO, Norton TT. Comparison of Infrared photoretinoscope and autorefractor in tree shrews with and without induced myopia. Optom Vis Sci. 2003;80(suppl.):120.
29. Norton TT, Wu WW, Siegwart JT Jr. Refractive state of tree shrew eyes measured with cortical visual evoked potentials. Optom Vis Sci. 2003;:80:623-631.
30. Glickstein M, Millodot M. Retinoscopy and eye size. Science. 1970;168:605-606.
31. Norton TT. Experimental myopia in tree shrews. In: Bock G, Widdows K, eds. Myopia and the Control of Eye Growth. Chichester, UK: Wiley;1990:178-194.
32. Siegwart JT Jr, Norton TT. The susceptible period for deprivation-induced myopia in tree shrew. Vision Res. 1998;38:3505-3515.
33. Gwiazda J, Thorn F, Bauer J, Held R. Emmetropization and the progression of manifest refraction in children followed from infancy to puberty. Clin Vision Sci. 1993;8:337-344.
34. 1 muscarinic antagonist pirenzepine reduces myopia and eye enlargement in the tree shrew. Invest Ophthalmol Vis Sci. 1996;37:1368-1379.
35. Napper GA, Brennan NA, Barrington M, et al. The duration of normal visual exposure necessary to prevent form deprivation myopia in chicks. Vision Res. 1995;35:1337-1344.
36. Napper GA, Brennan NA, Barrington M, et al. The effect of an interrupted daily period of normal visual stimulation on form deprivation myopia in chicks. Vision Res. 1997;37:1557-1564.
37. Winawer J, Wallman J. Temporal constraints on lens compensation in chicks. Vision Res. 2002;42:2651-2668.
38. Park TW, Winawer J, Wallman J. Further evidence that chick eyes use the sign of blur in spectacle lens compensation. Vision Res. 2003;43:1519-1531.
39. Zhu X, Park TW, Winawer J, Wallman J. In a matter of minutes, the eye can know which way to grow. Invest Ophthalmol Vis Sci. 2005;46:2238-2241.
40. Phillips JR, Khalaj M, McBrien NA. Induced myopia associated with increased scleral creep in chick and tree shrew eyes. Invest Ophthalmol Vis Sci. 2000;41:2028-2034.
41. Rada JA, Shelton S, Norton TT. The sclera and myopia. Exp Eye Res. 2006;82:185-200.
42. Kee CS, Marzani D, Wallman J. Differences in time course and visual requirements of ocular responses to lenses and diffusers. Invest Ophthalmol Vis Sci. 2001;42:575-583.
43. Gwiazda J, Thorn F, Bauer J, Held R. Myopic children show insufficient accommodative response to blur. Invest Ophthalmol Vis Sci. 1993;34:690-694.
44. Leung JT, Brown B. Progression of myopia in Hong Kong Chinese schoolchildren is slowed by wearing progressive lenses. Optom Vis Sci. 1999;76:346-354.
45. Gwiazda J, Hyman L, Hussein M, et al. A randomized clinical trial of progressive addition lenses versus single vision lenses on the progression of myopia in children. Invest Ophthalmol Vis Sci. 2003;44:1492-1500.
46. Morgan I, Megaw P. Using natural STOP growth signals to prevent excessive axial elongation and the development of myopia. Ann Acad Med Singapore. 2004;33:16-20.
47. Chung K, Mohidin N, O'Leary DJ. Undercorrection of myopia enhances rather than inhibits myopia progression. Vision Res. 2002;42:2555-2559.
48. Phillips JR. Monovision slows juvenile myopia progression unilaterally. Br J Ophthalmol. 2005;89:1196-1200.