Preparation of novel antibacterial agents. Replacement of the central aromatic ring with heterocycles

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 8, 2007, Pages 2347-2350

  Li, Jianke ^a   Wakefield, Brian D ^a   Ruble, J Craig ^a   Stiff, Cory M ^a   Romero, Donna L ^a   Marotti, Keith R ^a   Sweeney, Michael T ^a   Zurenko, Gary E ^a   Rohrer, Douglas C ^a   Thorarensen, Atli ^a  

^a PFIZER INC   (United States)

Author keywords

Anthranilic acid; Antibacterial; Human serum albumin; Protein binding

Indexed keywords

ANTIINFECTIVE AGENT; BENZISOXAZOLE; BENZTHIAZOLE; INDOLE; ISOXAZOLE; OXAZOLE; SERUM ALBUMIN; SULFONAMIDE; THIAZOLE; UNCLASSIFIED DRUG; VANCOMYCIN;

ANTIBACTERIAL ACTIVITY; ARTICLE; DRUG ACTIVITY; DRUG POTENCY; HUMAN; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; STRUCTURE ANALYSIS;

ANTHRANILIC ACIDS; ANTI-BACTERIAL AGENTS; BACTERIA; HETEROCYCLIC COMPOUNDS; HUMANS; MICROBIAL SENSITIVITY TESTS; PROTEIN BINDING; SERUM ALBUMIN; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33947582618     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.12.055     Document Type: Article

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