Discovery and initial development of a novel class of antibacterials: Inhibitors of Staphylococcus aureus transcription/translation

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 24, 2006, Pages 6173-6177

  Larsen, Scott D ^a   Hester, Matthew R ^a   Craig Ruble, J ^a   Kamilar, Gregg M ^a   Romero, Donna L ^a   Wakefield, Brian ^a   Melchior, Earline P ^a   Sweeney, Michael T ^a   Marotti, Keith R ^a  

^a PFIZER INC   (United States)

Author keywords

Athranilic acid; Staphylococcus aureus

Indexed keywords

ANTHRANILIC ACID; ANTIBIOTIC AGENT; SULFONAMIDE;

ANTIBACTERIAL ACTIVITY; ARTICLE; CHEMICAL MODIFICATION; CORRELATION ANALYSIS; DRUG MECHANISM; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; MINIMUM INHIBITORY CONCENTRATION; PHARMACOLOGICAL BLOCKING; SOLID; STRUCTURE ANALYSIS; TRANSCRIPTION REGULATION; TRANSLATION REGULATION;

ANTI-BACTERIAL AGENTS; MODELS, MOLECULAR; PROTEIN BIOSYNTHESIS; STAPHYLOCOCCUS AUREUS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTION, GENETIC;

BACTERIA (MICROORGANISMS); STAPHYLOCOCCUS AUREUS;

EID: 33750741920     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.09.044     Document Type: Article

References (9)

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