High-throughput quantitation of nefazodone and its metabolites in human plasma by high flow direct-injection LC-MS/MS

Journal of Pharmaceutical and Biomedical Analysis

Volumn 43, Issue 5, 2007, Pages 1808-1819

  Mao, Yan ^a   Huang, Mike Qingtao ^a   Xia, Yuan Qing ^a   Jemal, Mohammed ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

Direct injection; High throughput; LC MS MS; Nafazodone quantitation; On line extraction

Indexed keywords

(3 CHLOROPHENYL)PIPERAZINE; BMS 180492; DRUG METABOLITE; HYDROXYNEFAZODONE; NEFAZODONE; UNCLASSIFIED DRUG;

ACCURACY; ARTICLE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG ISOLATION; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN TISSUE; LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY; VALIDATION PROCESS;

ANTIDEPRESSIVE AGENTS, SECOND-GENERATION; CHROMATOGRAPHY, LIQUID; HUMANS; MOLECULAR STRUCTURE; PIPERAZINES; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY; TIME FACTORS; TRIAZOLES;

EID: 33947513312     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2006.11.041     Document Type: Article

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