A novel role for the Fc receptor γ subunit: Enhancement of FcγR ligand affinity

Journal of Experimental Medicine

Volumn 183, Issue 5, 1996, Pages 2227-2233

  Miller, Kathy L ^a   Duchemin, Anne Marie ^a   Anderson, Clark L ^a  

^a THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FC RECEPTOR; MEMBRANE RECEPTOR;

ANTIBODY AFFINITY; ARTICLE; BINDING AFFINITY; CELL CULTURE; CELL MEMBRANE; FLOW CYTOMETRY; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; LIGAND BINDING; PLASMID; PRIORITY JOURNAL; RECEPTOR AFFINITY; RECEPTOR BINDING; SCATCHARD PLOT; SIGNAL TRANSDUCTION;

3T3 CELLS; ANIMALS; BASE SEQUENCE; CELL LINE; CERCOPITHECUS AETHIOPS; DNA PRIMERS; HUMANS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN ISOTYPES; KINETICS; MACROMOLECULAR SUBSTANCES; MICE; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; RECEPTORS, IGG; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 0029953055     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.183.5.2227     Document Type: Article

References (22)

1. Ravetch, J.V., and C.L. Anderson. 1990. Fcγ receptor family: proteins, transcripts, and genes. In Fc Receptors and the Action of Antibodies. H. Metzger, editor. American Society for Microbiology, Washington, D.C. 211-235.
2. Ravetch, J.V., and J.-P. Kinet. 1991. Fc receptors. Annu. Rev. Immunol. 9:457-492.
3. Ernst, L.K., A.-M. Duchemin, and C.L. Anderson. 1993. Association of the high affinity receptor for IgG (FcγRI) with the gamma subunit of the IgE receptor. Proc. Natl. Acad. Sci. USA. 90:6023-6027.
4. Ra, C., M.-H. Jouvin, J. Blank, and J.-P. Kinet. 1989. A macrophage Fcγ receptor and the mast cell receptor for IgE share an identical subunit. Nature (Lond.). 341:752-754.
5. Pfefferkorn, L.C., and G.R. Yeaman. 1994. Association of IgA-Fc receptors (FcαR) with FcεRIγ2 subunits in U937 cells. J. Immunol. 153:3228-3236.
6. Blank, U., C. Ra, L. Miller, K. White, H. Metzger, and J.-P. Kinet. 1989. Complete structure and expression in transfected cells of high affinity IgE receptor. Nature (Lond.). 337: 187-189.
7. Hibbs, M.L., P. Selvaraj, O. Carpen, T.A. Springer, H. Kuster, M.-H.E. Jouvin, and J.-P. Kinet. 1989. Mechanisms for regulating expression of membrane isoforms of FcγRIII (CD16). Science (Wash. DC). 246:1608-1611.
8. Allen, J.M., and B. Seed. 1989. Isolation and expression of functional high-affinity Fc receptor complementary DNAs. Science (Wash. DC). 243:378-381.
9. Maliszewski, C.R., C.J. March, M.A. Schoenborn, S. Gimpel, and L. Shen. 1990. Expression cloning of a human Fc receptor for IgA. J. Exp. Med. 172:1665-1672.
10. Van de Winkel, J.G.J., and P.J.A. Capel. 1993. Human IgG Fc receptor heterogeneity: molecular aspects and clinical implications. Immunol. Today. 14:215-221.
11. Anderson, C.L., and G.N. Abraham. 1980. Characterization of the Fc receptor for IgG on a human macrophage cell line, U937. J. Immunol. 125:2735-2741.
12. Unkeless, J.C., and H.N. Eisen. 1975. Binding of monomeric immunoglobulins to Fc receptors of mouse macrophages. J. Exp. Med. 142:1520-1533.
13. Hullet, M.D., N. Osman, I.D.C. McKenzie, and P.M. Hogarth. 1991. Chimeric Fc receptors identify functional domains of the murine high affinity receptor for IgG. J. Immunol. 147:1863-1868.
14. Sears, D.W., N. Osman, B. Tate, I.F.C. McKenzie, and P.M. Hogarth. 1990. Molecular cloning and expression of the mouse high affinity Fc receptor for IgG. J. Immunol. 144: 371-378.
15. Kuster, H., H. Thompson, and J.-P. Kinet. 1990. Characterization and expression of the gene for the human Fc receptor γ subunit. J. Biol. Chem. 265:6448-6452.
16. Kurosaki, T., I. Gander, and J.V. Ravetch. 1991. A subunit common to an IgG Fc receptor and the T-cell receptor mediates assembly through different interactions. Proc. Natl. Acad. Sci. USA. 88:3837-3841.
17. Kurosaki, T., and J.V. Ravetch. 1989. A single amino acid in the glycosyl phosphatidylinositol attachment domain determines the membrane topology of FcγRIII. Nature (Lond.). 342:805-807.
18. Kishimoto, T., S. Akira, and T. Taga. 1992. Interleukin-6 and its receptor: a paradigm for cytokines. Science (Wash. DC). 258:593-596.
19. Nicola, N.A., and D. Metcalf. 1991. Subunit promiscuity among hematopoietic growth factor receptors. Cell. 67:1-4.
20. Tinggui, Y.T., M.L.-S. Taga, M.L.-S. Tsang, K. Yasukawa, T. Kishimoto, and Y.-C. Yang. 1993. Involvement of IL-6 signal transducer gp130 in IL-11-mediated signal transduction. J. Immunol. 151:2555-2561.
21. Noguchi, M., Y. Nakamura, S.M. Russell, S.F. Ziegler, M. Tsang, X. Cao, and W.J. Leonard. 1993. Interleukin-2 receptor γ chain: a functional component of the interleukin-7 receptor. Science (Wash. DC). 262:1877-1880.
22. Russel, S.M., A.D. Keegan, N. Harada, Y. Nakamura, M. Noguchi, P. Leland, M.C. Friedmann, A. Miyajima, R.K. Puri, W.E. Paul, and W.J. Leonard. 1993. Interleukin-2 receptor γ chain: a functional component of the interleukin-4 receptor. Science (Wash. DC). 262:1880-1883.