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Volumn 109, Issue 7, 2007, Pages 1376-1383

Comorbidity is an independent predictor of complete remission in elderly patients receiving induction chemotherapy for acute myeloid leukemia

Author keywords

Acute myeloid leukemia; Comorbidity; Elderly; Induction chemotherapy

Indexed keywords

ANTHRACYCLINE; ANTINEOPLASTIC AGENT; CD34 ANTIGEN; CYTARABINE; DAUNORUBICIN; IDARUBICIN; LOMUSTINE; MELPHALAN; MERCAPTOPURINE; METHOTREXATE; TOPOTECAN;

EID: 33947499161     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.22537     Document Type: Article
Times cited : (134)

References (38)
  • 1
    • 0029916143 scopus 로고    scopus 로고
    • Treatment of newly-diagnosed acute myelogenous leukaemia in patients aged 80 years and above
    • DeLima M, Ghaddar H, Pierce S, Estey E. Treatment of newly-diagnosed acute myelogenous leukaemia in patients aged 80 years and above. Br J Haematol. 1996;93:89-95.
    • (1996) Br J Haematol , vol.93 , pp. 89-95
    • DeLima, M.1    Ghaddar, H.2    Pierce, S.3    Estey, E.4
  • 2
    • 0031846076 scopus 로고    scopus 로고
    • Acute myeloid leukemia in the elderly: A critical review of therapeutic approaches and appraisal of results of therapy
    • Ferrara F, Mirto S, Zagonel V, Pinto A. Acute myeloid leukemia in the elderly: a critical review of therapeutic approaches and appraisal of results of therapy. Leuk Lymphoma. 1998;29(3-4):375-382.
    • (1998) Leuk Lymphoma , vol.29 , Issue.3-4 , pp. 375-382
    • Ferrara, F.1    Mirto, S.2    Zagonel, V.3    Pinto, A.4
  • 3
    • 0035469856 scopus 로고    scopus 로고
    • Attempts to improve treatment outcomes in acute myeloid leukemia (AML) in older patients: The results of the United Kingdom Medical Research Council AML11 trial
    • Goldstone AH, Burnett AK, Wheatley K, Smith AG, Hutchinson RM, Clark RE. Attempts to improve treatment outcomes in acute myeloid leukemia (AML) in older patients: the results of the United Kingdom Medical Research Council AML11 trial. Blood. 2001;98:1302-1311.
    • (2001) Blood , vol.98 , pp. 1302-1311
    • Goldstone, A.H.1    Burnett, A.K.2    Wheatley, K.3    Smith, A.G.4    Hutchinson, R.M.5    Clark, R.E.6
  • 4
    • 0024458031 scopus 로고
    • On the value of intensive remission-induction chemotherapy in elderly patients of 65+ years with acute myeloid leukemia: A randomized phase III study of the European Organization for Research and Treatment of Cancer Leukemia Group
    • Lowenberg B, Zittoun R, Kerkhofs H, et al. On the value of intensive remission-induction chemotherapy in elderly patients of 65+ years with acute myeloid leukemia: a randomized phase III study of the European Organization for Research and Treatment of Cancer Leukemia Group. J Clin Oncol. 1989;7:1268-1274.
    • (1989) J Clin Oncol , vol.7 , pp. 1268-1274
    • Lowenberg, B.1    Zittoun, R.2    Kerkhofs, H.3
  • 6
    • 33644521267 scopus 로고    scopus 로고
    • Results of intensive chemotherapy in 998 patients age 65 years or older with acute myeloid leukemia or high-risk myelodysplastic syndrome: Predictive prognostic models for outcome
    • Kantarjian H, O'Brien S, Cortes J, et al. Results of intensive chemotherapy in 998 patients age 65 years or older with acute myeloid leukemia or high-risk myelodysplastic syndrome: predictive prognostic models for outcome. Cancer. 2006;106:1090-1098.
    • (2006) Cancer , vol.106 , pp. 1090-1098
    • Kantarjian, H.1    O'Brien, S.2    Cortes, J.3
  • 7
    • 9144238671 scopus 로고    scopus 로고
    • A phase 3 study of three induction regimens and of priming with GM-CSF in older adults with acute myeloid leukemia: A trial by the Eastern Cooperative Oncology Group
    • Rowe JM, Neuberg D, Friedenberg W, et al. A phase 3 study of three induction regimens and of priming with GM-CSF in older adults with acute myeloid leukemia: a trial by the Eastern Cooperative Oncology Group. Blood. 2004;103:479-485.
    • (2004) Blood , vol.103 , pp. 479-485
    • Rowe, J.M.1    Neuberg, D.2    Friedenberg, W.3
  • 8
    • 0036892524 scopus 로고    scopus 로고
    • Outcome after induction chemotherapy for older patients with acute myeloid leukemia is not improved with mitoxantrone and etoposide compared to cytarabine and daunorubicin: A Southwest Oncology Group study
    • Anderson JE, Kopecky KJ, Willman CL, et al. Outcome after induction chemotherapy for older patients with acute myeloid leukemia is not improved with mitoxantrone and etoposide compared to cytarabine and daunorubicin: a Southwest Oncology Group study. Blood. 2002;100:3869-3876.
    • (2002) Blood , vol.100 , pp. 3869-3876
    • Anderson, J.E.1    Kopecky, K.J.2    Willman, C.L.3
  • 9
    • 0029068452 scopus 로고
    • A controlled study of recombinant human granulocyte colony-stimulating factor in elderly patients after treatment for acute myelogenous leukemia. AML Cooperative Study Group
    • Dombret H, Chastang C, Fenaux P, et al. A controlled study of recombinant human granulocyte colony-stimulating factor in elderly patients after treatment for acute myelogenous leukemia. AML Cooperative Study Group. N Engl J Med. 1995;332:1678-1683.
    • (1995) N Engl J Med , vol.332 , pp. 1678-1683
    • Dombret, H.1    Chastang, C.2    Fenaux, P.3
  • 11
    • 0034877489 scopus 로고    scopus 로고
    • Acute myeloid leukemia in the elderly: Biology and therapeutic strategies
    • Pinto A, Zagonel V, Ferrara F. Acute myeloid leukemia in the elderly: biology and therapeutic strategies. Crit Rev Oncol Hematol. 2001;39:275-287.
    • (2001) Crit Rev Oncol Hematol , vol.39 , pp. 275-287
    • Pinto, A.1    Zagonel, V.2    Ferrara, F.3
  • 12
    • 0034050269 scopus 로고    scopus 로고
    • Treatment of acute myelogenous leukemia in older adults
    • Rowe JM. Treatment of acute myelogenous leukemia in older adults. Leukemia. 2000;14:480-487.
    • (2000) Leukemia , vol.14 , pp. 480-487
    • Rowe, J.M.1
  • 13
    • 8944259891 scopus 로고    scopus 로고
    • De novo AML with dysplastic hematopoiesis: Cytogenetic and prognostic significance
    • Gahn B, Haase D, Unterhalt M, et al. De novo AML with dysplastic hematopoiesis: cytogenetic and prognostic significance. Leukemia. 1996;10:946-951.
    • (1996) Leukemia , vol.10 , pp. 946-951
    • Gahn, B.1    Haase, D.2    Unterhalt, M.3
  • 14
    • 33646404606 scopus 로고    scopus 로고
    • Age and acute myeloid leukemia
    • Appelbaum FR, Gundacker H, Head DR, et al. Age and acute myeloid leukemia. Blood. 2006;107:3481-3485.
    • (2006) Blood , vol.107 , pp. 3481-3485
    • Appelbaum, F.R.1    Gundacker, H.2    Head, D.R.3
  • 15
    • 0033179095 scopus 로고    scopus 로고
    • Frequency and clinical significance of the expression of the multidrug resistance proteins MDR1/P-glycoprotein, MRP1, and LRP in acute myeloid leukemia: A Southwest Oncology Group study
    • Leith CP, Kopecky KJ, Chen IM, et al. Frequency and clinical significance of the expression of the multidrug resistance proteins MDR1/P-glycoprotein, MRP1, and LRP in acute myeloid leukemia: a Southwest Oncology Group study. Blood. 1999;94:1086-1099.
    • (1999) Blood , vol.94 , pp. 1086-1099
    • Leith, C.P.1    Kopecky, K.J.2    Chen, I.M.3
  • 17
    • 0034283695 scopus 로고    scopus 로고
    • Estey EH. How I treat older patients with AML. Blood. 2000;96:1670-1673.
    • Estey EH. How I treat older patients with AML. Blood. 2000;96:1670-1673.
  • 18
    • 23844502627 scopus 로고    scopus 로고
    • Pretreatment prognostic factors and treatment outcome in elderly patients with de novo acute myeloid leukemia
    • Chen CC, Yang CF, Yang MH, et al. Pretreatment prognostic factors and treatment outcome in elderly patients with de novo acute myeloid leukemia. Ann Oncol. 2005;16:1366-1373.
    • (2005) Ann Oncol , vol.16 , pp. 1366-1373
    • Chen, C.C.1    Yang, C.F.2    Yang, M.H.3
  • 20
    • 0030728202 scopus 로고    scopus 로고
    • Validation of the Charlson comorbidity index in patients with head and neck cancer: A multi-institutional study
    • Singh B, Bhaya M, Stern J, et al. Validation of the Charlson comorbidity index in patients with head and neck cancer: a multi-institutional study. Laryngoscope. 1997;107(11 pt 1): 1469-1475.
    • (1997) Laryngoscope , vol.107 , Issue.11 PART 1 , pp. 1469-1475
    • Singh, B.1    Bhaya, M.2    Stern, J.3
  • 21
    • 27544440149 scopus 로고    scopus 로고
    • Charlson comorbidity index as a predictor of long-term outcome after surgery for nonsmall cell lung cancer
    • Birim O, Kappetein AP, Bogers AJ. Charlson comorbidity index as a predictor of long-term outcome after surgery for nonsmall cell lung cancer. Eur J Cardiothorac Surg. 2005; 28:759-762.
    • (2005) Eur J Cardiothorac Surg , vol.28 , pp. 759-762
    • Birim, O.1    Kappetein, A.P.2    Bogers, A.J.3
  • 22
    • 0032751381 scopus 로고    scopus 로고
    • Management of acute myeloid leukemia in elderly patients
    • Hiddemann W, Kern W, Schoch C, et al. Management of acute myeloid leukemia in elderly patients. J Clin Oncol. 1999;17:3569-3576.
    • (1999) J Clin Oncol , vol.17 , pp. 3569-3576
    • Hiddemann, W.1    Kern, W.2    Schoch, C.3
  • 23
    • 3843131824 scopus 로고    scopus 로고
    • Comparing morbidity and mortality of HLA-matched unrelated donor hematopoietic cell transplantation after nonmyeloablative and myeloablative conditioning: Influence of pretransplantation comorbidities
    • Sorror ML, Maris MB, Storer B, et al. Comparing morbidity and mortality of HLA-matched unrelated donor hematopoietic cell transplantation after nonmyeloablative and myeloablative conditioning: influence of pretransplantation comorbidities. Blood. 2004;104:961-968.
    • (2004) Blood , vol.104 , pp. 961-968
    • Sorror, M.L.1    Maris, M.B.2    Storer, B.3
  • 24
    • 3042782698 scopus 로고    scopus 로고
    • The benefit of induction chemotherapy in patients age ≥75 years
    • Vey N, Coso D, Bardou VJ, et al. The benefit of induction chemotherapy in patients age ≥75 years. Cancer. 2004; 101:325-331.
    • (2004) Cancer , vol.101 , pp. 325-331
    • Vey, N.1    Coso, D.2    Bardou, V.J.3
  • 25
    • 0028979666 scopus 로고
    • Prognostic significance of karyotype in de novo adult acute myeloid leukemia. The BGMT Group
    • Dastugue N, Payen C, Lafage-Pochitaloff M, et al. Prognostic significance of karyotype in de novo adult acute myeloid leukemia. The BGMT Group. Leukemia. 1995;9:1491-1498.
    • (1995) Leukemia , vol.9 , pp. 1491-1498
    • Dastugue, N.1    Payen, C.2    Lafage-Pochitaloff, M.3
  • 26
    • 0023092594 scopus 로고
    • A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation
    • Charlson ME, Pompei P Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987;40:373-383.
    • (1987) J Chronic Dis , vol.40 , pp. 373-383
    • Charlson, M.E.1    Pompei, P.2    Ales, K.L.3    MacKenzie, C.R.4
  • 27
    • 0034010518 scopus 로고    scopus 로고
    • Measuring comorbidity in older cancer patients
    • Extermann M. Measuring comorbidity in older cancer patients. Eur J Cancer. 2000;36:453-471.
    • (2000) Eur J Cancer , vol.36 , pp. 453-471
    • Extermann, M.1
  • 28
    • 0032884937 scopus 로고    scopus 로고
    • Topotecan and cytarabine is an active combination regimen in myelodysplastic syndromes and chronic myelomonocytic leukemia
    • Beran M, Estey E, O'Brien S, et al. Topotecan and cytarabine is an active combination regimen in myelodysplastic syndromes and chronic myelomonocytic leukemia. J Clin Oncol. 1999;17:2819-2830.
    • (1999) J Clin Oncol , vol.17 , pp. 2819-2830
    • Beran, M.1    Estey, E.2    O'Brien, S.3
  • 29
    • 0025363943 scopus 로고
    • Treatment of acute myeloid leukemia in elderly patients: The influence of maintenance therapy (BGM 84 protocol) [in French]
    • Montastruc M, Reiffers J, Stoppa AM, et al. Treatment of acute myeloid leukemia in elderly patients: the influence of maintenance therapy (BGM 84 protocol) [in French]. Nouv Rev Fr Hematol. 1990;32:147-152.
    • (1990) Nouv Rev Fr Hematol , vol.32 , pp. 147-152
    • Montastruc, M.1    Reiffers, J.2    Stoppa, A.M.3
  • 30
    • 1542753559 scopus 로고    scopus 로고
    • Revised recommendations of the International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid Leukemia
    • Cheson BD, Bennett JM, Kopecky KJ, et al. Revised recommendations of the International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid Leukemia. J Clin Oncol. 2003;21:4642-4649.
    • (2003) J Clin Oncol , vol.21 , pp. 4642-4649
    • Cheson, B.D.1    Bennett, J.M.2    Kopecky, K.J.3
  • 31
    • 33845382806 scopus 로고
    • Nonparametric estimation for incomplete estimation
    • Kaplan E, Meier P. Nonparametric estimation for incomplete estimation. J Am Stat Assoc. 1958;53:457-462.
    • (1958) J Am Stat Assoc , vol.53 , pp. 457-462
    • Kaplan, E.1    Meier, P.2
  • 32
    • 0017365573 scopus 로고
    • Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. Analysis and examples
    • Peto R, Pike MC, Armitage P, et al. Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. Analysis and examples. Br J Cancer. 1977;35:1-39.
    • (1977) Br J Cancer , vol.35 , pp. 1-39
    • Peto, R.1    Pike, M.C.2    Armitage, P.3
  • 33
    • 0022635770 scopus 로고
    • Microcomputer-based nonlinear regression analysis of ligand-binding data: Application of Akaike's information criterion
    • Kamikubo K, Murase H, Murayama M, Miura K. Microcomputer-based nonlinear regression analysis of ligand-binding data: application of Akaike's information criterion. Jpn J Pharmacol. 1986;40:342-346.
    • (1986) Jpn J Pharmacol , vol.40 , pp. 342-346
    • Kamikubo, K.1    Murase, H.2    Murayama, M.3    Miura, K.4
  • 34
    • 0031901577 scopus 로고    scopus 로고
    • Comorbidity and functional status are independent in older cancer patients
    • Extermann M, Overcash J, Lyman GH, Parr J, Balducci L. Comorbidity and functional status are independent in older cancer patients. J Clin Oncol. 1998;16:1582-1587.
    • (1998) J Clin Oncol , vol.16 , pp. 1582-1587
    • Extermann, M.1    Overcash, J.2    Lyman, G.H.3    Parr, J.4    Balducci, L.5
  • 35
    • 0026639706 scopus 로고
    • Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases
    • Deyo RA, Cherkin DC, Ciol MA. Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases. J Clin Epidemiol. 1992;45:613-619.
    • (1992) J Clin Epidemiol , vol.45 , pp. 613-619
    • Deyo, R.A.1    Cherkin, D.C.2    Ciol, M.A.3
  • 36
    • 0033849596 scopus 로고    scopus 로고
    • Measurement and impact of comorbidity in older cancer patients
    • Extermann M. Measurement and impact of comorbidity in older cancer patients. Crit Rev Oncol Hematol. 2000;35: 181-200.
    • (2000) Crit Rev Oncol Hematol , vol.35 , pp. 181-200
    • Extermann, M.1
  • 37
    • 4444368514 scopus 로고    scopus 로고
    • Morbidity and mortality with nonmyeloablative compared with myeloablative conditioning before hematopoietic cell transplantation from HLA-matched related donors
    • Diaconescu R, Flowers CR, Storer B, et al. Morbidity and mortality with nonmyeloablative compared with myeloablative conditioning before hematopoietic cell transplantation from HLA-matched related donors. Blood. 2004;104: 1550-1558.
    • (2004) Blood , vol.104 , pp. 1550-1558
    • Diaconescu, R.1    Flowers, C.R.2    Storer, B.3
  • 38
    • 23944440464 scopus 로고    scopus 로고
    • Hematopoietic cell transplantation (HCT)-specific comorbidity index: A new tool for risk assessment before allogeneic HCT
    • Sorror ML, Maris MB, Storb R, et al. Hematopoietic cell transplantation (HCT)-specific comorbidity index: a new tool for risk assessment before allogeneic HCT. Blood. 2005; 106:2912-2919.
    • (2005) Blood , vol.106 , pp. 2912-2919
    • Sorror, M.L.1    Maris, M.B.2    Storb, R.3


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