Measurement and impact of comorbidity in older cancer patients

Critical Reviews in Oncology/Hematology

Volumn 35, Issue 3, 2000, Pages 181-200

  Extermann, Martine ^a  

^a H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

Author keywords

Aged; Aged > 80; Apache III; Cancer; Charlson; CIRS; CIRS G; Comorbidity; ICED; Kaplan Feinstein; Support

Indexed keywords

AGED; AGING; CANCER; CANCER CHEMOTHERAPY; CANCER MORTALITY; COMORBIDITY; FUNCTIONAL ASSESSMENT; HUMAN; MEDICAL DECISION MAKING; PROGNOSIS; QUALITY OF LIFE; REVIEW;

EID: 0033849596     PISSN: 10408428     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1040-8428(00)00090-1     Document Type: Article

References (80)

1. Fried L.P., Bandeen-Roche K., Kasper J.D., Guralnik J.M. Association of comorbidity with disability in older women: the women's health and aging study. J. Clin. Epidemiol. 52:1999;27-37.
2. Yancik R. Epidemiology of cancer in the elderly. Current status and projections for the future. Rays. 22:(S1):1997;3-9.
3. Extermann M., Overcash J., Lyman G.H., Parr J., Balducci L. Comorbidity and functional status are independent in older cancer patients. J. Clin. Oncol. 16:1998;1582-1587.
4. Monfardini S., Sorio R., Hoctin Boes G., Kaye S., Serraino D. Entry and evaluation of elderly patients in European Organization for Research and Treatment of Cancer (EORTC) new-drug-development studies. Cancer. 76:1995;333-338.
5. Trimble E.L., Carter C.L., Cain D., Freidlinn B., Undergleider R.S., Friedman M.A. Representation of older patients in cancer treatment trials. Cancer. 74:1994;2208-2214.
6. Extermann M. Measuring comorbidity in older cancer patients. Eur J Cancer 2000;36:453-71.
7. Satariano W.A., Ragland D.R. The effect of comorbidity on 3-year survival of women with primary breast cancer. Ann. Intern. Med. 120:1994;104-110.
8. Yancik R., Wesley M.N., Ries L.A.G., et al. Comorbidity and age as predictors of risk for early mortality in male and female colon carcinoma patients. Cancer. 82:1998;2123-2134.
9. Charlson M.E., Pompei P., Ales K., MacKenzie C.R. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J. Chron. Dis. 40:1987;373-383.
10. Linn B.S., Linn M.W., Gurel L. Cumulative illness rating scale. J. Am. Geriatr. Soc. 16:1968;622-666.
11. Knaus W.A., Wagner D.P., Draper E.A., et al. The APACHE III prognostic system. Chest. 100:1991;1619-1636.
12. Deyo R.A., Cherkin D.C., Ciol M.A. Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases. J. Clin. Epidemiol. 45:1992;613-619.
13. D'Hoore W., Sicotte C., Tilquin C. Risk adjustment in outcome assessment: the Charlson comorbidity index. Methods Inf. Med. 32:1993;382-387.
14. Romano P.S., Roos L.L., Jollis J.G. Adapting a clinical comorbidity index for use with ICD-9-CM administrative data: differing perspectives. J. Clin. Epidemiol. 46:1993;1075-1090.
15. Incalzi R.A., Capparella O., Gemma A., et al. The interaction between age and comorbidity contributes to predicting the mortality of geriatric patients in the acute-care hospital. J. Intern. Med. 242:1997;291-298.
16. Kaplan M.H., Feinstein A.R. The importance of classifying initial co-morbidity in evaluating the outcome of diabetes mellitus. J. Chron. Dis. 27:1974;387-404.
17. Parmelee P.A., Katz I.R., Lawton M.P. The relation of pain to depression among institutionalized aged. J. Gerontol. 46:1991;P15-P21.
18. Conwell Y., Forbes N.T., Cox C., Caine E.D. Validation of a measure of physical illness burden at autopsy: the cumulative illness rating scale. J. Am. Geriatr. Soc. 41:1993;38-41.
19. Miller M.D., Paradis C.F., Houck P.R., et al. Rating chronic medical illness burden in geropsychiatric practice and research: application of the cumulative illness rating scale. Psychiatry Res. 41:1992;237-248.
20. Charlson M., Szatrowski T.P., Peterson J., Gold J. Validation of a comorbidity index. J. Clin. Epidemiol. 47:1994;1245-1251.
21. Greenfield S., Blanco D.M., Elashoff R.M., Ganz P. Patterns of care related to age of breast cancer patients. J. Am. Med. Assoc. 257:1987;2766-2770.
22. Extermann M., Regamey C., Humair L., Murisier F., Rhyner K., Vonwiller H.M. Initial treatment of sepsis in non-neutropenic patients: ceftazidime alone versus 'best guess' combined antibiotic therapy. Chemotherapy. 41:1995;306-315.
23. Knaus W.A., Harrel F.E., Lynn J., et al. The SUPPORT prognostic model. Ann. Intern. Med. 122:1995;191-203.
24. Waldman E., Potter J.F. A prospective evaluation of the cumulative illness rating scale. Aging (Milano). 4:1992;171-178.
25. Parmelee P.A., Thuras P.D., Katz I.R., Lawton M.P. Validation of the cumulative illness rating scale in a geriatric residential population. J. Am. Geriatr. Soc. 43:1995;130-137.
26. Lyness J.M., Caine E.D., Conwell Y., King D.A., Cox C. Depressive symptoms, medical illness, and functional status in depressed psychiatric patients. Am. J. Psychiatry. 150:1993;910-915.
27. McCormick W.C., Kukull W.A., van Belle G., Bowen J.D., Teri L., Larson E.B. Symptom patterns and comorbidity in the early stages of Alzheimer's disease. J. Am. Geriatr. Soc. 42:1994;517-521.
28. Pompei P., Charlson M.E., Ales K., McKenzie C.R., Norton M. Relating patient characteristics at the time of admission to outcomes of hospitalization. J. Clin. Epidemiol. 10:1991;1063-1069.
29. Melfi C., Holleman E., Arthur D., Katz B. Selecting a patient characteristics index for the prediction of medical outcomes using administrative claims data. J. Clin. Epidemiol. 48:1995;917-926.
30. Cleves M.A., Sanchez N., Draheim M. Evaluation of two competing methods for calculating Charlson's comorbidity index when analysing short-term mortality using administrative data. Clin. Epidemiol. 50:1997;903-908.
31. Poses R.M., McClish D.K., Smith W.R., Bekes C., Scott W.E. Prediction of survival of critically ill patients by admission comorbidity. Clin. Epidemiol. 49:1996;743-747.
32. Rochon P.A., Katz J.N., Morrow L.A., et al. Comorbid illness is associated with survival and length of hospital stay in patients with chronic disability. Med. Care. 34:1996;1093-1101.
33. Matsui K., Goldman L., Johnson P.A., Kuntz K.M., Cook E.F., Lee T.H. Comorbidity as a correlate of length of stay for hospitalized patients with acute chest pain. J. Gen. Intern. Med. 11:1996;262-268.
34. Monane M., Kanter D.S., Glynn R.J., Avorn J. Variability in length of hospitalization for stroke. Arch. Neurol. 53:1996;875-880.
35. Kieszak S.M., Flanders W.D., Kosinski A.S., Shipp C.C., Karp H. A comparison of the Charlson comorbidity index derived from medical record data and administrative billing data. J. Clin. Epidemiol. 52:1999;137-142.
36. Di Iorio A., Longo A.L., Costanza M., Bandinelli S., Capasso S., Gigante M., Bavazzano A., Guizzardi G., Senin U., Ferrucci L., Abate G. Characteristics of geriatric patients related to early and late readmissions to hospital. Aging Clin. Exp. Res. 10:1998;339-346.
37. Librero J., Peiro S., Ordinana R. Chronic comorbidity and outcomes of hospital care: length of stay, mortality, and readmission at 30 and 365 days. J. Clin. Epidemiol. 52:1999;171-179.
38. Waite K., Oddone E., Weinberger M., et al. Lack of association between patient's measured burden of disease and risk for hospital readmission. J. Clin. Epidemiol. 47:1994;1229-1236.
39. Bates D.W., Pruess K., Souney P., Platt R. Serious falls in hospitalized patients: correlates and resource utilization. Am. J. Med. 99:1999;137-143.
40. Lawrence V.A., Dhanda R., Hilsenbeck S.G., Page C.P. Risk of pulmonary complications after elective abdominal surgery. Chest. 110:1996;744-750.
41. Rabeneck L., Feinstein A.R., Horwitz R.I., Wells C.K. A new clinical prognostic staging system for acute pancreatitis. Am. J. Med. 95:1993;61-70.
42. Singh B., Cordeiro P.G., Santamaria E., Shaha A.R., Pfister D.G., Shah J.P. Factors associated with complications in microvascular reconstruction of head and neck defects. Plast. Reconstr. Surg. 103:1999;403-411.
43. Gitter M.J., Jaeger T.M., Petterson T.M., Gersh B.J., Silverstein M.D. Bleeding and thromboembolism during anticoagulant therapy: a population-based study in Rochester, MN. Mayo Clin. Proc. 70:1995;725-733.
44. Singh B., Bhaya M., Stern J., Roland J.T., Zimbler M., Rosenfeld R.M., Har-El G., Lucente F.E. Validation of the Charlson comorbidity index in patients with head and neck cancer: a multi-institutional study. Laryngoscope. 107:1997;1469-1475.
45. Newschaffer C.J., Bush T.L., Penberthy L.T. Comorbidity measurement in elderly female breast cancer patients with administrative and medical records data. J. Clin. Epidemiol. 50:1997;725-733.
46. Krousel-Wood M.A., Abdoh A., Re R. Comparing comorbid-illness indices assessing outcome variation: the case of prostatectomy. J. Gen. Intern. Med. 11:1996;32-38.
47. Ghali W.A., Hall R.E., Rosen A.K., Ash A.S., Moskowitz M.A. Searching for an improved clinical comorbidity index for use in ICD-9-CM administrative data. Clin. Epidemiol. 49:1996;273-278.
48. Piccirillo J.F. Inclusion of comorbidity in a staging system for head and neck cancer. Oncology. 9:1995;831-836.
49. Newschaffer C.J., Bush T.L., Penberthy L.E., Bellantoni M., Helzlsour K., Diener-West M. Does comorbid disease interact with cancer? An epidemiologic analysis of mortality in a cohort of elderly breast cancer patients. J. Gerontol. 53:1998;M372-M378.
50. Guadagnoli E., Shapiro C., Gurwitz J.H., et al. Age-related patterns of care: evidence against ageism in the treatment of early-stage breast cancer. J. Clin. Oncol. 15:1997;2338-2344.
51. Bennett C.L., Greenfield S., Aronow H., Ganz P., Vogelzang N.J., Elashoff R.M. Patterns of care related to age of men with prostate cancer. Cancer. 67:1991;2633-2641.
52. Clemens J.D., Feinstein A.R., Holabird N., Cartwright S. A new clinical-anatomic staging system for evaluating prognosis and treatment of prostatic cancer. J. Chron. Dis. 39:1986;913-928.
53. Balducci L., Extermann M. Cancer chemotherapy in the older person: what the medical oncologist needs to know. Cancer. 80:1997;1317-1322.
54. Extermann M., Balducci L., Lyman G.H. What threshold for adjuvant therapy in older breast cancer patients? J. Clin. Oncol. 18:2000;1709-17.
55. Keller B.K., Potter J.F. Predictors of mortality in outpatient geriatric evaluation and management clinic patients. J. Gerontol. 49:1994;M246-M251.
56. Cowen M.E., Simpson S., Vettese T.E. Survival estimates for patients with abnormal swallowing studies. J. Gen. Intern. Med. 12:1997;88-94.
57. West D.W., Satariano W.A., Ragland D.R., Hiatt R.A. Comorbidity and breast cancer survival: a comparison between black and white women. Ann. Epidemiol. 6:1996;413-419.
58. Skiest D.J., Rubinstein E., Carley N., Gioiella L., Lyons R. The importance of comorbidity in HIV-infected patients over 55: a retrospective case-control study. Am. J. Med. 101:1996;605-611.
59. Chin M.H., Goldman L. Gender differences in 1-year survival and quality of life among patients admitted with congestive heart failure. Med. Care. 36:1998;1033-1046.
60. Covinsky K.E., Kahana E., Chin M.H., Palmer R.M., Fortinsky R.H., Landefeld C.S. Depressive symptoms and 3-year mortality in older hospitalized medical patients. Ann. Intern. Med. 130:1999;563-569.
61. Zincke H., Bergstrahl E.J., Blute M.L., et al. Radical prostatectomy for clinically localized prostate cancer: long-term results of 1143 patients from a single institution. J. Clin. Oncol. 12:1994;2254-2263.
62. Ballard-Barbash R., Potosky A.L., Harlan L.C., Nayfield S.G., Kessler L.G. Factors associated with surgical and radiation therapy for early stage breast cancer in older women. J. Natl. Cancer Inst. 88:1996;716-726.
63. Grasso M.E., Weller W.E., Shaffer T.J., Diette G.B., Anderson G.F. Capitation, managed care, and chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 158:1998;133-138.
64. Karp H.R., Flanders W.D., Shipp C.C., Taylor B., Martin D. Carotid endarterectomy among medicare beneficiaries. Stroke. 29:1998;46-52.
65. Pompei P., Charlson M.E., Douglas G. Clinical assessments as predictors of 1 year survival after hospitalization: implications for prognostic stratification. J. Clin. Epidemiol. 41:1988;275-284.
66. Singh B., Bhaya M., Zimbler M., Stern J., Roland J.T., Rosenfeld R.M., Har-El G., Lucente F.E. Impact of comorbidity on outcome of young patients with head and neck squamous cell carcinoma. Head Neck. 20:1998;1-7.
67. Albertsen PC, Fryback DG, Storer BE, Kolon TF, Fine J. Long-term survival among men with conservatively treated localized prostate cancer. J Am Med Assoc 274:626-31.
68. Linn MW, Linn BS, Gurel L. Physical resistance in the aged. Geriatrics 1967;134-38.
69. Parmelee P.A., Katz I.R., Lawton M.P. Depression and mortality among institutionalized aged. J. Gerontol. 47:1992;P3-P10.
70. Macario A., Vitez T.S., Dunn B., McDonald T., Brown B. Hospital costs and severity of illness in three types of elective surgery. Anesthesiology. 86:1997;92-100.
71. Bearden D.M., Allman R.M., Vasan Sundarum S., Burst N.M., Bartolucci A.A. Age-related variability in the use of cardiovascular imaging procedures. J. Am. Geriatr. Soc. 41:1993;1075-1082.
72. Muder R.R., Brennen C., Swenson D.L., Wagener M. Pneumonia in a long-term care facility. A prospective study of outcome. Arch. Intern. Med. 156:1996;2365-2370.
73. Covinsky K.E., Justice A.C., Rosenthal G.E., Palmer R.M., Landefeld C.S. Measuring prognosis and case mix in hospitalized elders. J. Gen. Intern. Med. 12:1997;203-208.
74. Roos L.L., Stranc L., James R.C., Li J. Complications, comorbidities, and mortality: improving classification and prediction. Health Serv. Res. 32:1997;229-242.
75. Kiefe C.I., Funkhouser E., Fouad M.N., May D.S. Chronic disease as a barrier to breast and cervical cancer screening. J. Gen. Intern. Med. 13:1998;357-365.
76. Damiano A.M., Bergner M., Draper E., Knaus W.A., Wagner D.P. Reliability of a measure of severity of illness: acute physiology of chronic health evaluation-II. J. Clin. Epidemiol. 45:1992;93-101.
77. Polderman K.H., Thijs L.G., Girbes A.R.J. Interobserver variability in the use of Apache II scores. Lancet. 353:1999;380.
78. Katz J.N., Chang L.C., Sangha O., Fossel A.H., Bates D.W. Can comorbidity be measured by questionnaire rather than medical record review? Med. Care. 34:1996;73-84.
79. Liu M., Domen K., Chino N. Comorbidity measures for stroke outcome research: a preliminary study. Arch. Phys. Med. Rehabil. 78:1997;166-172.
80. Imamura K., McKinnon M., Middleton R., Black N. Reliability of a comorbidity measure: the index of coexistent disease (ICED). J. Clin. Epidemiol. 50:1997;1011-1016.