Biochemical analysis of Thermotoga maritima GH36 α-galactosidase (TmGalA) confirms the mechanistic commonality of clan GH-D glycoside hydrolases

Biochemistry

Volumn 46, Issue 11, 2007, Pages 3319-3330

  Comfort, Donald A ^a   Bobrov, Kirill S ^b   Ivanen, Dina R ^b   Shabalin, Konstantin A ^b   Harris, James M ^a   Kulminskaya, Anna A ^b   Brumer, Harry ^c   Kelly, Robert M ^a  

^a North Carolina State University   (United States)

^b PETERSBURG NUCLEAR PHYSICS INSTITUTE   (Russian Federation)

^c ALBANOVA UNIVERSITY CENTER   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ANOMERIC STEREOCHEMISTRY; GLYCOSIDE HYDROLASE (GH); MECHANISTIC COMMONALITY;

ADDITION REACTIONS; BIOCHEMISTRY; CATALYST ACTIVITY; MUTAGENS; PH EFFECTS; STEREOCHEMISTRY;

ENZYMES;

4 NITROPHENYLGALACTOSIDE; ALPHA GALACTOPYRANOSIDE; ALPHA GALACTOSIDASE; ASPARTIC ACID; AZIDE; GLUCOPYRANOSIDE; GLYCINE; GLYCOSIDASE; MUTANT PROTEIN; PYRANOSIDE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME KINETICS; ENZYME MECHANISM; ENZYME STRUCTURE; HYDROLYSIS; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN FAMILY; SITE DIRECTED MUTAGENESIS; STEREOCHEMISTRY; THERMOTOGA MARITIMA;

ALPHA-GALACTOSIDASE; AMINO ACID SEQUENCE; AZIDES; CATALYSIS; CLONING, MOLECULAR; HEAT; HYDROGEN-ION CONCENTRATION; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN DENATURATION; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY; THERMOTOGA MARITIMA;

THERMOTOGA MARITIMA;

EID: 33947433621     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi061521n     Document Type: Article

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