Identification of a basic region on tissue factor that interacts with the first epidermal growth factor-like domain of factor X

Biochemistry

Volumn 46, Issue 11, 2007, Pages 3193-3199

  Manithody, Chandrashekhara ^a   Yang, Likui ^a   Rezaie, Alireza R ^a  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; BIOLOGICAL MEMBRANES; GROWTH KINETICS; MUTAGENESIS; SUBSTRATES;

ACTIVATION COMPLEXES; EPIDERMAL GROWTH; MUTANTS; TISSUE FACTOR (TF);

TISSUE;

BLOOD CLOTTING FACTOR 10; BLOOD CLOTTING FACTOR 7A; EPIDERMAL GROWTH FACTOR; THROMBOPLASTIN;

AMINO ACID SUBSTITUTION; ARTICLE; CARBOXY TERMINAL SEQUENCE; ENZYME ACTIVATION; HUMAN; HUMAN CELL; KINETICS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN INTERACTION;

ALANINE; AMINO ACID SUBSTITUTION; ARGININE; ASPARAGINE; EPIDERMAL GROWTH FACTOR; FACTOR VIIA; FACTOR X; HUMANS; LYSINE; MODELS, MOLECULAR; PROTEIN STRUCTURE, TERTIARY; THROMBOPLASTIN;

EID: 33947401039     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi6025193     Document Type: Article

References (31)

1. Bode, W., Mayr, I., Baumann, U., Huber, R., Stone, S. R., and Hofsteenge, J. (1989) The refined 1.9 Å crystal structure of human α-thrombin: Interaction with D-Phe-Pro-Arg chlorometheylketone and significance of the Tyr-Pro-Pro-Trp insertion segment, EMBO J. 8, 3467-3475.
2. Morrissey, J. H., Neuenschwander, P. F., Huang, Q., McCallum, C. D., Bixia, S., and Johnson, A. E. (1997) Factor VIIa-tissue factor: Functional importance of protein-membrane interactions, Thromb. Haemostasis 78, 112-116.
3. Jackson, C. M., and Nemerson, Y. (1980) Blood coagulation, Annu. Rev. Biochem. 49, 765-811.
4. Morrissey, J. H., Fakhrai, H., and Edgington, T. S. (1987) Molecular cloning of the cDNA for tissue factor, the cellular receptor for the initiation of the coagulation protease cascade, Cell 50, 129-135.
5. Harlos, K., Martin, D. M. A., O'Brien, D. P., Jones, E. Y., Stuart, D. I., Polikarpov, I., Miller, A., Tuddnham, E. G. D., and Boys, C. W. G. (1994) Crystal structure of the extracellular region of human tissue factor, Nature 370, 662-666.
6. Muller, Y. A., Ultsch, M. H., Kelley, R. F., and de Vos, A. M. (1994) Structure of the extracellular domain of human tissue factor: Location of the factor VIIa binding site, Biochemistry 33, 10864-10870.
7. Ruf, W., Schullek, J. R., Stone, M. J., and Edgington, T. S. (1994) Mutational mapping of functional residues in tissue factor: Identification of factor VII recognition determinants in both structural modules of the predicted cytokine receptor homology domain, Biochemistry 33, 1565-1572.
8. Kelly, C. R., Schullek, J. R., Ruf, W., and Edgington, T. S. (1996) Tissue factor residue Asp44 regulates catalytic function of the bound proteinase factor VIIa, Biochem. J. 315, 145-151.
9. Rezaie, A. R., Fiore, M. M., Neuenschwander, P. F., Esmon, C. T., and Morrissey, J. H. (1992) Expression and purification of a soluble tissue factor fusion protein with an epitope for an unusual calcium-dependent antibody, Protein Expression Purif. 3, 453-460.
10. Kirchofer, D., Lipari, M. T., Moran, P., Eigenbrot, C., and Kelley, R. F. (2000) The tissue factor region that interacts with substrates factor IX and factor X, Biochemistry 39, 7380-7387.
11. Silverberg, S. A., Nemerson, Y., and Zur, M. (1977) Kinetics of the activation of bovine coagulation factor X by components of the extrinsic pathway. Kinetic behavior of two-chin factor VII in the presence and absence of tissue factor, J. Biol. Chem. 252, 8481-8488.
12. Banner, D. W., D'Arcy, A., Chene, C., Winkler, F. K., Guha, A., Konigsberg, W. H., Nemerson, Y., and Kirchofer, D. (1996) The crystal structure of the complex of blood coagulation factor VIIa with soluble tissue factor, Nature 380, 41-46.
13. McCallum, C. D., Su, B., Neuenschwander, P. F., Morrissey, J. H., and Johnson, A. E. (1997) Tissue factor positions and maintains the factor VIIa active site far above the membrane surface even in the absence of the factor VIIa Gla domain, J. Biol. Chem. 272, 30160-30166.
14. Norledge, B. V., Petrovan, R. J., Ruf, W., and Olson, A. J. (2003) The tissue factor/factor VIIa/factor Xa complex: A model built by docking and site-directed mutagenesis, Proteins 53, 640-648.
15. Venkateswarlu, D., Duke, R. E., Perera, L., Darden, T. A., and Pedersen, L. G. (2003) An all-atom solution-equilibrated model of human extrinsic blood coagulation complex (sTF-VIIa-Xa): A protein-protein docking and molecular dynamics refinement study, J. Thromb. Haemostasis 1, 2577-2588.
16. Furie, B., and Furie, B. C. (1988) The molecular basis of blood coagulation, Cell 53, 505-518.
17. Stenflo, J. (1991) Structure-function relationships of epidermal growth factor modules in vitamin K-dependent clotting factors, Blood 78, 1637-1651.
18. Dickinson, C. D., Kelly, C. R., and Ruf, W. (1996) Identification of surface residues mediating tissue factor binding and catalytic function of the serine protease factor VIIa, Proc. Natl. Acad. Sci. U.S.A. 93, 14379-14384.
19. Ruf, W., Miles, D. J., Rehemtulla, A., and Edgington, T. S. (1992) Cofactor residues lysine 165 and 166 are critical for protein substrate recognition by the tissue factor-factor VIIa protease complex, J. Biol. Chem. 267, 6375-6381.
20. Huang, Q., Neuenschwander, P. F., Rezaie, A. R., and Morrissey, J. H. (1996) Substrate recognition by tissue factor-factor VIIa, J. Biol. Chem. 271, 21752-21757.
21. Zhong, D., Bajaj, M. S., Schmidt, A. E., and Bajaj, S. P. (2002) The N-terminal epidermal growth factor-like domain in factor IX and factor X represents an important recognition motif for binding to tissue factor, J. Biol. Chem. 277, 3622-3631.
22. Kittur, F. S., Manithody, C., Morrissey, J. H., and Rezaie, A. R. (2004) The cofactor function of the N-terminal domain of tissue factor, J. Biol. Chem. 279, 39745-39749.
23. Rezaie, A. R., Manithody, C., and Yang, L. (2005) Identification of factor Xa residues critical for interaction with protein Z-dependent protease inhibitor, J. Biol. Chem. 280, 32722-32728.
24. Rezaie, A. R., Neuenschwander, P. F., Morrissey, J. H., and Esmon, C. T. (1993) Analysis of the functions of the first epidermal growth factor-like domain of factor X, J. Biol. Chem. 268, 8176-8180.
25. Yang, L., Manithody, C., and Rezaie, A. R. (2002) Contribution of basic residues of the 70-80-loop to heparin binding and anticoagulant function of activated protein C, Biochemistry 41, 6149-6157.
26. Smirnov, M. D., and Esmon, C. T. (1994) Phosphatidylethanolamine incorporation into vesicles selectively enhances factor Va inactivation by activated protein C, J. Biol. Chem. 269, 816-819.
27. + and factor Va in the prothrombinase complex, J. Biol. Chem. 279, 48262-48269.
28. Shobe, J., Dickinson, C. D., Edgington, T. S., and Ruf, W. (1999) Macromolecular substrate affinity for the tissue factor-factor VIIa complex is independent of scissile bond docking, J. Biol. Chem. 274, 24171-24175.
29. Baugh, R. J., Dickinson, C. D., Ruf, W., and Krishnaswamy, S. (2000) Exosite Interactions determine the affinity of factor X for the extrinsic Xase complex, J. Biol. Chem. 275, 28826-28833.
30. Ruf, W., Miles, D. J., Rehemtulla, A., and Edgington, T. S. (1992) Tissue factor residues 157-167 are required for efficient proteolytic activation of factor X and factor VII, J. Biol. Chem. 267, 22206-22210.
31. Ullner, M., Selander, M., Persson, E., Stenflo, J., Drakenberg, T., and Teleman, O. (1992) Three-dimensional structure of the apo form of the N-terminal EGF-like module of blood coagulation factor X as determined by NMR spectroscopy and simulated folding, Biochemistry 31, 5974-5983.