FurA modulates gene expression of alr3808, a DpsA homologue in Nostoc (Anabaena) sp. PCC7120

FEBS Letters

Volumn 581, Issue 7, 2007, Pages 1351-1356

  Hernández, José A ^a   Pellicer, Silvia ^a   Huang, Lionel ^a   Peleato, M Luisa ^a   Fillat, María F ^a  

^a UNIVERSITY OF ZARAGOZA   (Spain)

Author keywords

Cyanobacteria; DpsA; Ferric uptake regulator; Fur; Iron stress; Nutritional stress; Oxidative stress

Indexed keywords

DNA BINDING PROTEIN; FERRIC ION; GENE PRODUCT; PROTEIN DPSA; PROTEIN FURA; UNCLASSIFIED DRUG;

ALR3808 GENE; ANABAENA; ARTICLE; BACTERIAL GENE; BINDING AFFINITY; CONTROLLED STUDY; CYANOBACTERIUM; DPSA GENE; FURA GENE; GEL MOBILITY SHIFT ASSAY; GENE; GENE EXPRESSION REGULATION; IN VITRO STUDY; IN VIVO STUDY; MUTANT; NONHUMAN; NOSTOC; NUTRITION; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FAMILY; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; PROTEIN TARGETING;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; BASE SEQUENCE; DNA-BINDING PROTEINS; DOWN-REGULATION; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GENE EXPRESSION REGULATION, BACTERIAL; MOLECULAR SEQUENCE DATA; NOSTOC; PROMOTER REGIONS (GENETICS); REPRESSOR PROTEINS;

CYANOBACTERIA; NOSTOC SP.;

EID: 33947398462     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2007.02.053     Document Type: Article

References (25)

1. Pena M.M., and Bullerjahn G.S. The DpsA protein of Synechococcus sp. strain PCC7942 is a DNA-binding hemoprotein. Linkage of the Dps and bacterioferritin protein families. J. Biol. Chem. 270 (1995) 22478-22482
2. Gupta S., and Chatterji D. Bimodal protection of DNA by Mycobacterium smegmatis DNA-binding protein from stationary phase cells. J. Biol. Chem. 278 (2003) 5235-5241
3. Sen A., Dwivedi K., Rice K.A., and Bullerjahn G.S. Growth phase and metal-dependent regulation of the dpsA gene in Synechococcus sp. strain PCC 7942. Arch. Microbiol. 173 (2000) 352-357
4. Dwivedi K., Sen A., and Bullerjahn G.S. Expression and mutagenesis of the dpsA gene of Synechococcus sp. PCC7942, encoding a DNA-binding protein involved in oxidative stress protection. FEMS Microbiol. Lett. 155 (1997) 85-91
5. Altuvia S., Almiron M., Huisman G., Kolter R., and Storz G. The dps promoter is activated by OxyR during growth and by IHF and sigma S in stationary phase. Mol. Microbiol. 13 (1994) 265-272
6. Gruber T.M., and Bryant D.A. Characterization of the alternative sigma-factors SigD and SigE in Synechococcus sp. strain PCC 7002. SigE is implicated in transcription of post-exponential-phase-specific genes. Arch. Microbiol. 169 (1998) 211-219
7. Michel K.P., Berry S., Hifney A., Kruip J., and Pistorius E.K. Adaptation to iron deficiency: a comparison between the cyanobacterium Synechococcus elongatus PCC 7942 wild-type and a DpsA-free mutant. Photosynth. Res. 75 (2003) 71-84
8. Chen L., and Helmann J.D. Bacillus subtilis MrgA is a Dps (PexB) homologue: evidence for metalloregulation of an oxidative-stress gene. Mol. Microbiol. 18 (1995) 295-300
9. Bsat N., Herbig A., Casillas-Martinez L., Setlow P., and Helmann J.D. Bacillus subtilis contains multiple Fur homologues: identification of the iron uptake (Fur) and peroxide regulon (PerR) repressors. Mol. Microbiol. 29 (1998) 189-198
10. Hernández J.A., Peleato M.L., Fillat M.F., and Bes M.T. Heme binds to and inhibits the DNA-binding activity of the global regulator FurA from Anabaena sp. PCC 7120. FEBS Lett. 577 (2004) 35-41
11. Hernández J.A., et al. The conformational stability and thermodynamics of Fur A (ferric uptake regulator) from Anabaena sp. PCC 7119. Biophys. J. 89 (2005) 4188-4200
12. Hernández J.A., Muro-Pastor A.M., Flores E., Bes M.T., Peleato M.L., and Fillat M.F. Identification of α furA cis antisense RNA in the cyanobacterium Anabaena sp. PCC 7120. J. Mol. Biol. 355 (2006) 325-334
13. Rippka R., Deruelles J.B., Waterbury M., Herdman M., and Stanier R.Y. Genetics assignments, strain stories and properties of pure cultures of cyanobacteria. J. Gen. Microbiol. 11 (1979) 1-61
14. Bes M.T., Hernández J.A., Peleato M.L., and Fillat M.F. Cloning, overexpression and interaction of recombinant Fur from the cyanobacterium Anabaena PCC 7119 with isiB and its own promoter. FEMS Microbiol. Lett. 194 (2001) 187-192
15. Hernández J.A., Bes M.T., Fillat M.F., Neira J.L., and Peleato M.L. Biochemical analysis of the recombinant Fur (ferric uptake regulator) protein from Anabaena PCC 7119: factors affecting its oligomerization state. Biochem. J. 366 (2002) 315-322
16. Towbin H., Staehelin T., and Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. USA 76 (1979) 4350-4354
17. Hernández J.A., Lopez-Gomollón S., Muro-Pastor A., Valladares A., Bes M.T., Peleato M.L., and Fillat M.F. Interaction of FurA from Anabaena sp. PCC 7120 with DNA: a reducing environment and the presence of Mn(2+) are positive effectors in the binding to isiB and furA promoters. Biometals 19 (2006) 259-268
18. Escolar L., Perez-Martin J., and de Lorenzo V. Binding of the Fur (ferric uptake regulator) repressor of Escherichia coli to arrays of the GATAAT sequence. J. Mol. Biol. 283 (1998) 537-547
19. Valsangiacomo C., Baggi F., Gaia V., Balmelli T., Peduzzi R., and Piffaretti J.C. Use of amplified fragment length polymorphism in molecular typing of Legionella pneumophila and application to epidemiological studies. J. Clin. Microbiol. 33 (1995) 1716-1719
20. Cai Y.P., and Wolk C.P. Use of a conditionally lethal gene in Anabaena sp. strain PCC 7120 to select for double recombinants and to entrap insertion sequences. J. Bacteriol. 172 (1990) 3138-3145
21. Strauss N. Iron deprivation: physiology and gene regulation. In: Bryant D.A. (Ed). The Molecular Biology of Cyanobacteria (1994), Kluwer
22. Ochsner U.A., Wilderman P.J., Vasil A.I., and Vasil M.L. GeneChip expression analysis of the iron starvation response in Pseudomonas aeruginosa: identification of novel pyoverdine biosynthesis genes. Mol. Microbiol. 45 (2002) 1277-1287
23. Baichoo N., Wang T., Ye R., and Helmann J.D. Global analysis of the Bacillus subtilis Fur regulon and the iron starvation stimulon. Mol. Microbiol. 45 (2002) 1613-1629
24. Frenkiel-Krispin D., et al. Regulated phase transitions of bacterial chromatin: a non-enzymatic pathway for generic DNA protection. EMBO J. 20 (2001) 1184-1191
25. Durham K.A., and Bullerjahn G.S. Immunocytochemical localization of the stress-induced DpsA protein in the cyanobacterium Synechococcus sp. strain PCC 7942. J. Basic Microbiol. 42 (2002) 367-372