Activation by zonisamide, a newer antiepileptic drug, of large-conductance calcium-activated potassium channel in differentiated hippocampal neuron-derived H19-7 cells

Journal of Pharmacology and Experimental Therapeutics

Volumn 321, Issue 1, 2007, Pages 98-106

  Huang, Chin Wei ^a   Huang, Chao Ching ^a   Wu, Sheng Nan ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ACTIVATED POTASSIUM CHANNEL; CALCIUM CHANNEL L TYPE; PAXILLINE; POTASSIUM CHANNEL; RILUZOLE; VOLTAGE GATED CALCIUM CHANNEL; ZONISAMIDE;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL MEMBRANE CONDUCTANCE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENTIATION; ION CONDUCTANCE; NERVE CELL DIFFERENTIATION; NERVE EXCITABILITY; NERVE POTENTIAL; NERVE STIMULATION; NONHUMAN; PATCH CLAMP; POTASSIUM CURRENT; PRIORITY JOURNAL; RAT;

ACTION POTENTIALS; ANTICONVULSANTS; CALCIUM; CALCIUM CHANNELS, L-TYPE; CELL DIFFERENTIATION; CELL LINE; ELECTROPHYSIOLOGY; HIPPOCAMPUS; HUMANS; ISOXAZOLES; KINETICS; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MODELS, STATISTICAL; NEURONS; PATCH-CLAMP TECHNIQUES; PYRAMIDAL CELLS;

EID: 33947382940     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.106.116954     Document Type: Article

References (39)

1. Baulac M (2006) Introduction to zonisamide. Epilepsy Res 68S:S3-S9.
2. 2+-ATPase-1. Mol Endocrinol 16:1629-1637.
3. Butler A, Tsunoda S, McCobb DP, Wei A, and Salkoff L (1993) mSlo, a complex mouse gene encoding "maxi" calcium-activated potassium channels. Science (Wash DC) 261:221-224.
4. Castro PA, Cooper EC, Lowenstein DH, and Baraban SC (2001) Hippocampal heterotopia lack functional Kv4.2 potassium channels in the methylazoxymethanol model of cortical malformation and epilepsy. J Neurosci 21:6626-6634.
5. Du W, Bautista JF, Yang H, Diez-Sampedro A, You SA, Wang L, Kotagal P, Luders HO, Shi J, Cui J, et al. (2005) Calcium-sensitive potassium channelopathy in human epilepsy and paroxysmal movement disorder. Nat Genet 37:733-738.
6. Ermentrout GB (2002) Simulating, Analyzing, and Animating Dynamical System: A Guide to XPPAUT for Researchers and Students, Society for Industrial and Applied Mathematics, Philadelphia, PA.
7. Ghaemi SN, Zablotsky B, Filkowski MM, Dunn RT, Pardo TB, Isenstein E, and Baldassano CF (2006) An open prospective study of zonisamide in acute bipolar depression. J Clin Psychopharmacol 26:385-388.
8. Ghatta S, Nimmagadda D, Xu XP, and O'Rourke ST (2006) Large-conductance, calcium-activated potassium channels: structural and functional implications. Pharmacol Ther 110:103-116.
9. Gribkoff VK, Starrett JE Jr, Dworetzky SI, Hewawasam P, Boissard CG, Cook DA, Frantz SW, Heman K, Hibbard JR, Huston K, et al. (2001) Targeting acute ischemic stroke with a calcium-sensitive opener of maxi-K potassium channels. Nat Med 7:471-477.
10. Hong KW, Kim KY, Shin HK, Lee JH, Choi JM, Kwak YG, Kim CD, Lee WS, and Rhim BY (2003) Cilostazol prevents tumor necrosis factor-α-induced cell death by suppression of phosphatase and tension homolog deleted from chromosome 10 phosphorylation and activation. J Pharmacol Exp Ther 306:1182-1190.
11. Huang CW, Huang CC, Liu YC, and Wu SN (2004) Inhibitory effect of lamotrigine on A-type potassium current in hippocampal neuron-derived H19-7 cells. Epilepsia 45:729-736.
12. Huang CW, Huang CC, and Wu SN (2006) The opening effect of pregabalin on ATP-sensitive potassium channels in differentiated hippocampal neuron-derived H19-7 cells. Epilepsia 47:720-726.
13. Huang CW, Ueno S, Okada M, and Kaneko S (2005) Zonisamide at clinically relevant concentrations inhibits field EPSP but not presynaptic fiber volley in rat frontal cortex. Epilepsy Res 67:51-60.
14. Jang IS, Nakamura M, Ito Y, and Akaike N (2006) Presynaptic GABAa receptors facilitate spontaneous glutamate release from presynaptic terminals on mechanically dissociated rat CA3 pyramidal neurons. Neuroscience 138:25-35.
15. Kim B, Leventhal PS, Saltiel AR, and Feldman EL (1997) Insulin-like growth factor-I-mediated neurite outgrowth in vitro requires mitogen-activated protein kinase activation. J Biol Chem 272:21268-21273.
16. Knaus HG, McManus OB, Lee SH, Schmalhofer WA, Garcia-Calvo M, Helms LM, Sanchez M, Giangiacomo K, Reuben JP, and Smith AB 3rd (1994) Tremorogenic indole alkaloids potently inhibit smooth muscle high-conductance calciumactivated potassium channels. Biochemistry 33:5819-5828.
17. Laumonnier F, Roger S, Guerin P, Molinari F, M'rad R, Cahard D, Belhadj A, Halayem, Persico AM, Elia M, et al. (2006) Association of a functional deficit of the BKCa channel, a synaptic regulator of neuronal excitability, with autism and mental retardation. Am J Psychiatry 163:1622-1629.
18. Leppik IE (2004) Zonisamide: chemistry, mechanism of action, and pharmacokinetics. Seizure 13:S5-S9.
19. Morita S, Miwa H, and Kondo T (2005) Effect of zonisamide on essential tremor: a pilot crossover study in comparison with arotinolol. Parkinsonism Relat Disord 11:101-103.
20. Morrione A, Romano G, Navarro M, Reiss K, Valentinis B, Dews M, Eves E, Rosner MR, and Baserga R (2000) Insulin-like growth factor I receptor signaling in differentiation of neuronal H19-7 cells. Cancer Res 60:2263-2272.
21. Ondo WG (2006) Essential tremor: treatment options. Curr Treat Options Neurol 8:256-267.
22. Oommens KJ and Mathews S (1999) Zonisamide: a new anti-epileptic drug. Clin Neuropharmacol 22:192-200.
23. + channels. Pharmacol Biochem Behav 74:465-470.
24. + channels by meloxicam in the formalin test. Pharmacol Biochem Behav 81:725-731.
25. Peters DH and Sorkin EM (1993) Zonisamide: a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in epilepsy. Drugs 45:760-787.
26. Pinsky PF and Rinzel J (1994) Intrinsic and network rhythmogenesis in a reduced Traub model for CA3 neurons. J Comput Neurosci 1:39-60.
27. Rock DM, Macdonald RL, and Taylor CP (1989) Blockade of sustained repetitive action potentials in cultured spinal cord neurons by zonisamide (AD 810, CI 912), a novel anticonvulsant. Epilepsy Res 3:138-143.
28. Schauf CL (1987) Zonisamide enhances slow sodium inactivation in Myxicola. Brain Res 413:185-188.
29. + channels in spike broadening during repetitive firing in rat hippocampal pyramidal cells. J Physiol (Lond) 521:135-146.
30. Smith BL, McLeay LM, and Embling PP (1997) Effect of the mycotoxins penitrem, paxilline and lolitrem B on the electromyographic activity of skeletal and gastrointestinal smooth muscle of sheep. Res Vet Sci 62:111-116.
31. Storm JF (1990) Potassium currents in hippocampal pyramidal cells. Prog Brain Res 83:161-187.
32. Suzuki S, Kawakami K, Nishimura S, Watanabe Y, Yagi K, Seino M, and Miyamoto K (1992) Zonisamide blocks T-type calcium channel in cultured neurons of rat cerebral cortex. Epilepsy Res 12:21-27.
33. Tasaki K, Minami T, Ieiri I, Ohtsubo K, Hirakawa Y, Ueda K, and Higuchi S (1995) Drug interactions of zonisamide with phenytoin and sodium valproate: serum concentrations and protein binding. Brain Dev 17:182-185.
34. +-deficient rats. FASEB J 18:760-761.
35. 3 cells. Biochem Pharmacol 71:615-623.
36. 3 cells. J Investig Med 47:484-495.
37. 3 cells and pheochromocytoma PC12 cells. Endocrinology 145:1175-1184.
38. Wu SN, Wu AZ, and Lin MW (2006) Pharmacological roles of the large-conductance calcium-activated potassium channel. Curr Top Med Chem 6:1025-1030.
39. Yoshida S, Okada M, Zhu G, and Kaneko S (2005) Effects of zonisamide on neurotransmitter exocytosis associated with ryanodine receptors. Epilepsy Res 67:153-162.