The Kelch-like protein 1 modulates P/Q-type calcium current density

Neuroscience

Volumn 145, Issue 3, 2007, Pages 841-850

  Aromolaran, K A ^a   Benzow, K A ^b   Koob, M D ^b   Piedras Renteria E S ^a  

^a LOYOLA UNIVERSITY CHICAGO   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

actin binding protein; ataxia; calcium channel; kelch; SCA8; trinucleotide repeat

Indexed keywords

CALCIUM CHANNEL P TYPE; CALCIUM CHANNEL Q TYPE; KELCH LIKE PROTEIN 1; PROTEIN; UNCLASSIFIED DRUG;

ALLELE; ARTICLE; CELL STRUCTURE; CYTOSOL; DENDRITIC CELL; GENE LOCUS; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; KIDNEY CELL; MEMBRANE CURRENT; MOLECULAR EVOLUTION; MOLECULAR PROBE; NERVE FIBER GROWTH; PATCH CLAMP; PRIORITY JOURNAL; PURKINJE CELL; STEADY STATE; WHOLE CELL;

ACTION POTENTIALS; CALCIUM; CALCIUM CHANNELS, N-TYPE; CELL LINE; CELLS, CULTURED; CEREBELLUM; DENDRITES; DNA, COMPLEMENTARY; HUMANS; KIDNEY; KINETICS; MICROFILAMENT PROTEINS; NEURITES; NEURONS; SPINOCEREBELLAR ATAXIAS; SYNAPSES; TRANSFECTION;

EID: 33947331553     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2006.12.046     Document Type: Article

References (32)

1. Adams J., Kelso R., and Cooley L. The kelch repeat superfamily of proteins: propellers of cell function. Trends Cell Biol 10 (2000) 17-24
2. Aromolaran K.A., Benzow K.A., Cribbs L.L., Koob M.D., and Piedras-Reneria E.S. Modulation of T-type calcium currents by the Kelch-like 1 protein is mediated by actin (2006), Society for Neuroscience Annual Meeting, Atlanta, GA
3. Bardwell V.J., and Treisman R. The POZ domain: a conserved protein-protein interaction motif. Genes Dev 8 (1994) 1664-1677
4. Braybrook C., Warry G., Howell G., Arnason A., Bjornsson A., Moore G.E., Ross M.T., and Stanier P. Identification and characterization of KLHL4, a novel human homologue of the Drosophila Kelch gene that maps within the X-linked cleft palate and ankyloglossia (CPX) critical region. Genomics 72 (2001) 128-136
5. Cukovic D., Lu G.W., Wible B., Steele D.F., and Fedida D. A discrete amino terminal domain of Kv1.5 and Kv1.4 potassium channels interacts with the spectrin repeats of alpha-actinin-2. FEBS Lett 498 (2001) 87-92
6. Gerster U., Neuhuber B., Groschner K., Striessnig J., and Flucher B.E. Current modulation and membrane targeting of the calcium channel alpha1C subunit are independent functions of the beta subunit. J Physiol (Lond) 517 (1999) 353-368
7. He Y., Zu T., Benzow K.A., Orr H.T., Clark H.B., and Koob M.D. Targeted deletion of a single SCA8 ataxia locus allele in mice causes abnormal gait, progressive loss of motor coordination, and Purkinje cell dendritic deficits. J Neurosci 26 (2006) 9975-9982
8. Hille B. Ionic channels of excitable membranes (2001), Sinauer Associates, Sunderland, MA
9. Izumi Y., Maruyama H., Oda M., Morino H., Okada T., Ito H., Sasaki I., Tanaka H., Komure O., Udaka F., Nakamura S., and Kawakami H. SCA8 repeat expansion: large CTA/CTG repeat alleles are more common in ataxic patients, including those with SCA6. Am J Hum Genet 72 (2003) 704-709
10. Jun K., Piedras-Renteria E.S., Smith S.M., Wheeler D.B., Lee S.B., Lee T.G., Chin H., Adams M.E., Scheller R.H., Tsien R.W., and Shin H.S. Ablation of P/Q-type Ca(2+) channel currents, altered synaptic transmission, and progressive ataxia in mice lacking the alpha(1A)-subunit. Proc Natl Acad Sci U S A 96 (1999) 15245-15250
11. Koob M.D., Moseley M.L., Schut L.J., Benzow K.A., Bird T.D., Day J.W., and Ranum L.P. An untranslated CTG expansion causes a novel form of spinocerebellar ataxia (SCA8). Nat Genet 21 (1999) 379-384
12. Kordasiewicz H.B., Thompson R.M., Clark H.B., and Gomez C.M. C-termini of P/Q-type Ca2+ channel alpha1A subunits translocate to nuclei and promote polyglutamine-mediated toxicity. Hum Mol Genet 15 (2006) 1587-1599
13. Laezza F., Wilding T., Zhang X., Sequeira S., Huettner J., and Craig A.M. Expression and function of KRIP-6, a BTB/kelch protein binding to kinate receptors (2004), Society for Neuroscience Annual Meeting, San Diego, CA
14. Lim J., Hao T., Shaw C., Patel A.J., Szabo G., Rual J.F., Fisk C.J., Li N., Smolyar A., Hill D.E., Barabasi A.L., Vidal M., and Zoghbi H.Y. A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. Cell 125 (2006) 801-814
15. Maruoka N.D., Steele D.F., Au B.P., Dan P., Zhang X., Moore E.D., and Fedida D. Alpha-actinin-2 couples to cardiac Kv1.5 channels, regulating current density and channel localization in HEK cells. FEBS Lett 473 (2000) 188-194
16. Mortensen R., Chesnut J.D., Hoeffler J.P., and Kingston R.E. Introduction of DNA into mammalian cells. In: Ausubel F.M., et al. (Ed). Short protocols in molecular biology (1999), Wiley and Sons, New York 9.1-9.24
17. Moseley M.L., Zu T., Ikeda Y., Gao W., Mosemiller A.K., Daughters R.S., Chen G., Weatherspoon M.R., Clark H.B., Ebner T.J., Day J.W., and Ranum L.P. Bidirectional expression of CUG and CAG expansion transcripts and intranuclear polyglutamine inclusions in spinocerebellar ataxia type 8. Nat Genet 38 (2006) 758-769
18. Mutsuddi M., Marshall C.M., Benzow K.A., Koob M.D., and Rebay I. The spinocerebellar ataxia 8 noncoding RNA causes neurodegeneration and associates with staufen in Drosophila. Curr Biol 14 (2004) 302-308
19. Nahm S.S., Jung K.Y., Enger M.K., Griffith W.H., and Abbott L.C. Differential expression of T-type calcium channels in P/Q-type calcium channel mutant mice with ataxia and absence epilepsy. J Neurobiol 62 (2005) 352-360
20. Nemes J.P., Benzow K.A., Moseley M.L., Ranum L.P., and Koob M.D. The SCA8 transcript is an antisense RNA to a brain-specific transcript encoding a novel actin-binding protein (KLHL1). Hum Mol Genet 9 (2000) 1543-1551
21. Piedras-Renteria E.S., and Tsien R.W. Antisense oligonucleotides against alpha1E reduce R-type calcium currents in cerebellar granule cells. Proc Natl Acad Sci U S A 95 (1998) 7760-7765
22. 2+ channel currents arising from expanded trinucleotide repeats in spinocerebellar ataxia type 6. J Neurosci 21 (2001) 9185-9193
23. Prag S., and Adams J.C. Molecular phylogeny of the kelch-repeat superfamily reveals an expansion of BTB/kelch proteins in animals. BMC Bioinformatics 4 (2003) 42
24. Robinson D.N., and Cooley L. Drosophila kelch is an oligomeric ring canal actin organizer. J Cell Biol 138 (1997) 799-810
25. 2+ channel by the actin-binding proteins alpha-actinin and dystrophin. Am J Physiol Cell Physiol 282 (2002) C1502-C1511
26. Sakurai T., Hell J.W., Woppmann A., Miljanich G.P., and Catterall W.A. Immunochemical identification and differential phosphorylation of alternatively spliced forms of the alpha 1A subunit of brain calcium channels. J Biol Chem 270 (1995) 21234-21242
27. Seng S., Avraham H.K., Jiang S., Venkatesh S., and Avraham S. KLHL1/MRP2 mediates neurite outgrowth in a glycogen synthase kinase 3beta-dependent manner. Mol Cell Biol 26 (2006) 8371-8384
28. 2+-dependent inactivation. J Neurosci 22 (2002) 10142-10152
29. Walter J.T., Alvina K., Womack M.D., Chevez C., and Khodakhah K. Decreases in the precision of Purkinje cell pacemaking cause cerebellar dysfunction and ataxia. Nat Neurosci 9 (2006) 389-397
30. Winder S.J., and Ayscough K.R. Actin-binding proteins. J Cell Sci 118 (2005) 651-654
31. Zhuchenko O., Bailey J., Bonnen P., Ashizawa T., Stockton D.W., Amos C., Dobyns W.B., Subramony S.H., Zoghbi H.Y., and Lee C.C. Autosomal dominant cerebellar ataxia (SCA6) associated with small polyglutamine expansions in the alpha 1A-voltage-dependent calcium channel. Nat Genet 15 (1997) 62-69
32. Zollman S., Godt D., Prive G.G., Couderc J.L., and Laski F.A. The BTB domain, found primarily in zinc finger proteins, defines an evolutionarily conserved family that includes several developmentally regulated genes in Drosophila. Proc Natl Acad Sci U S A 91 (1994) 10717-10721