Dietary fish oil deactivates a growth-promoting signaling pathway in hepatoma 7288CTC in Buffalo rats

Nutrition and Cancer

Volumn 56, Issue 2, 2006, Pages 204-213

  Smith, Laura C ^a   Dauchy, Erin M ^a   Dauchy, Robert T ^a   Sauer, Leonard A ^a   Blask, David E ^a   Davidson, Leslie K ^a   Krause, Jean A ^a   Lynch, Darin T ^a  

^a BASSETT RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

8 BROMO CYCLIC AMP; CORN OIL; CYCLIC AMP; DNA; DOCOSAHEXAENOIC ACID; FATTY ACID; FISH OIL; ICOSAPENTAENOIC ACID; OLIVE OIL; PERTUSSIS TOXIN; THYMIDINE; TRITIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARACHIDONIC ACID METABOLISM; ARTICLE; CONTROLLED STUDY; DIETARY INTAKE; GROWTH INHIBITION; LIVER CELL CARCINOMA; MALE; NONHUMAN; RAT; SOLID TUMOR; TUMOR GROWTH;

ANIMALS; CARCINOMA, HEPATOCELLULAR; CELL DIVISION; CYCLIC AMP; DIETARY FATS, UNSATURATED; DNA, NEOPLASM; FISH OILS; LINOLEIC ACIDS; LIVER NEOPLASMS, EXPERIMENTAL; MALE; RANDOM ALLOCATION; RATS; RATS, INBRED BUF; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION;

RATTUS; RATTUS NORVEGICUS; RODENTIA; ZEA MAYS;

EID: 33947226069     PISSN: 01635581     EISSN: None     Source Type: Journal    
DOI: 10.1207/s15327914nc5602_11     Document Type: Article

References (41)

1. Karmali RA, Marsh J, and Fuchs C: Effect of omega-3 fatty acids on growth of a rat mammary tumor. J Natl Cancer Inst 73, 457-461, 1984.
2. Gabor H and Abraham S: Effect of dietary menhaden oil on tumor cell loss and the accumulation of mass of a transplantable mammary adenocarcinoma in BALB/c mice. J Natl Cancer Inst 76, 1223-1229, 1986.
3. Cannizzo F Jr and Broitman SA: Postpromotional effect of dietary marine or safflower oils on large bowel or pulmonary implants of CT-26 in mice. Cancer Res 49, 4289-4294, 1989.
4. Tisdale MJ and Dhesi JK: Inhibition of weight loss by ω-3 fatty acids in an experimental cachexia model. Cancer Res 50, 5022-5026, 1990.
5. Palakurthi SS, Flückiger R, Atkas H, Changolkar AK, Shahsafaei A, Harneit S, et al.: Inhibition of translation initiation mediates the antitumor effect of the n-3 polyunsaturated fatty acid eicosapentaenoic acid. Cancer Res 60, 2919-2925, 2000.
6. Rose DP and Connelly JM: Effects of dietary omega-3 fatty acids on human breast cancer growth and metastasis in nude mice. Natl Canc Inst 85, 1743-1747, 1993.
7. Welsch CW, Oakley CS, Chang CC, and Welsch MA: Suppression of growth by dietary fish oil of human breast carcinomas maintained in three different strains of immune-deficient mice. Nutr Cancer 20, 119-127, 1993.
8. Boudreau MD, Sohn KH, Rhee SH, Lee SW, Hunt JD, and Hwang DH: Suppression of tumor cell growth both in nude mice and in culture by n-3 polyunsaturated fatty acids: mediation through cyclooxygenase-independent pathways. Cancer Res 61, 1386-1391, 2001.
9. 2 induced ERK-1 and -2 and HIF-1α induction pathway. Carcinogenesis 25, 2303-2310, 2004.
10. Albino AP, Juan G, Traganos F, Reinhart L, Connolly J, Rose DP, et al.: Cell cycle arrest and apoptosis of melanoma cells by docosahexaenoic acid: association with decreased pRb phosphorylation. Cancer Res 60, 4139-4145, 2000.
11. Yonezawa T, Katoh K, and Obara, Y: Existence of GPR40 functioning in a human breast cancer cell line, MCF-7. Biochem Biophys Res Comm 314, 805-809, 2004.
12. Hardy S, St-Onge GG, Joly E, Langelier Y, and Prentki M: Oleate promotes the proliferation of breast cancer cells via the G protein-coupled receptor GPR40. J Biol Chem 280, 13285-13291, 2005.
13. Briscoe CP, Tadayyon M, Andrews JL, Benson WG, Chambers JK, et al.: The orphan G protein-coupled receptor GPR40 is activated by medium and long chain fatty acids. J Biol Chem 278, 11303-11311, 2003.
14. Kotarsky K, Nilsson NE, Flodgren E, Owman C, and Olde B: A human cell surface receptor activated by free fatty acids and thiazolidinedione drugs. Biochem Biophys Res Comm 301, 406-410, 2003.
15. Sauer LA, Dauchy RT, Blask DE, Krause JA, Davidson LK, and Dauchy EM: Eicosapentaenoic acid suppresses cell proliferation in MCF-7 human breast cancer xenografts in nude rats via a pertussis toxin-sensitive signal transduction pathway. J Nutr 135, 2124-2129, 2005.
16. Sauer LA, Dauchy RT, and Blask DE: Mechanism for the antitumor and anticachectic effects of n-3 fatty acids. Cancer Res 60, 5289-5295, 2000.
17. 3H]thymidine incorporation in hepatoma 7288CTC perfused in situ. Br J Cancer 66, 297-303, 1992.
18. Sauer LA, Dauchy RT, and Blask DE: Dietary linoleic acid intake controls the arterial blood plasma concentration and the rates of growth and linoleic acid uptake and metabolism in hepatoma 7288CTC in Buffalo rats. J Nutr 127, 1412-1421, 1997.
19. Blask DE, Dauchy RT, Sauer LA, Krause JA, and Brainard GC: Growth and fatty acid metabolism of human breast cancer (MCF-7) xenografts in nude rats: impact of constant light-induced nocturnal melatonin suppression. Breast Cancer Res Treat 79, 313-320, 2003.
20. Sauer LA, Stayman JW III, and Dauchy RT: Amino acid, glucose and lactic acid utilization in vivo by rat tumors. Cancer Res 42, 4090-4097, 1982.
21. Dauchy RT and Sauer LA: Preparation of "tissue-isolated" rat tumors for perfusion: a new surgical technique that preserves continuous blood flow. Lab Animal Sci 36, 678-681, 1986.
22. 14C] glucose. Metabolism 43, 1488-1497, 1994.
23. Sauer LA, Nagel WO, Dauchy RT, Miceli LA, and Austin JE: Stimulation of tumor growth in adult rats in vivo during an acute fast. Cancer Res 46, 3469-3475, 1986.
24. Sauer LA and Dauchy RT: Uptake of plasma lipids by tissue-isolated hepatoma 7288CTC and 7777 in vivo. Br J Cancer 66, 290-296, 1992.
25. Sauer LA, Dauchy RT, Blask DE, Armstrong BJ, and Scalist S: 13-Hydroxyoctadecadienoic acid is the mitogenic signal for linoleic acid-dependent growth in rat hepatoma 7288CTC in vivo. Cancer Res 59, 4688-4692, 1999.
26. Sauer LA, Dauchy RT, Blask DE, Krause JA, Davidson LK, et al.: Conjugated linoleic acid isomers and trans fatty acids inhibit fatty acid transport in hepatoma 7288CTC and inguinal fat pads in Buffalo rats. J Nutr 134, 1989-1997, 2004.
27. Bokoch GM, Katada T, Northrup JK, Hewlett EL, and Gilman AG: Identification of the predominant substrate for ADP-ribosylation by islet activating protein. J Biol Chem 258, 2072-2075, 1983.
28. Meyer RB Jr and Miller JP: Analogs of cyclic AMP and cyclic GMP: general methods of synthesis and the relationship of structure to enzymic activity. Life Sci 14, 1019-1040, 1974.
29. 3H- thymidine is a defective tool with which to measure rates of DNA synthesis. FASEB J July 1, 2002, 10.1096/fj.02-0142fje.
30. Sauer LA, Blask DE, and Dauchy, RT: Polyunsaturated fatty acids, melatonin and cancer prevention, Commentary. Biochem Pharm 61, 1455-1462, 2001.
31. Blask DE, Sauer LA, Dauchy RT, Holowachuk EW, Ruhoff MS, and Kopff HS: Melatonin inhibition of cancer growth in vivo involves suppression of tumor fatty acid metabolism via melatonin receptor-mediated signal transduction events. Cancer Res 59, 4693-4701, 1999.
32. Blask DE, Brainard GC, Dauchy RT, Hanifin JP, Davidson LK, et al.: Melatonin-depleted blood from premenopausal women exposed to light at night stimulates growth of human breast cancer xenografts in nude rats. Cancer Res 65, 11174-11184, 2005
33. Sauer LA, Dauchy RT, Blask DE, Davidson LK, Krause JA, et al.: Rosiglitazone and eicosatetraenoic acid cause a dose-dependent growth inhibition of rat hepatoma 7288CTC via an inhibitory G protein-coupled suppression of MEK1/2 and ERK1/2 phosphorylation [abst]. FASEB J 19, A517.3, 2005.
34. Chambrier C, Bastard J-P, Rieusset J, Chevillotte E, Bonnefont-Rousselot D, et al.: Eicosapentaenoic acid induces mRNA expression of peroxisome proliferator-activated receptor γ. Obesity Res 10, 518-525, 2002.
35. Fan Y-Y, Spencer TE, Wang N, Moyer MP, and Chapkin, RS: Chemopreventive n-3 fatty acids activate RXRα in colonocytes. Carcinogenesis 24, 1541-1548, 2003.
36. Sun H, Berquin IM, and Edwards IJ: Omega-3 polyunsaturated fatty acids regulate syndecan-1 expression in human breast cancer cells. Cancer Res 65, 4442-4447, 2005.
37. Barascu A, Besson P, Le Floch O, Bougnoux P, and Jourdan M-L: CDK1-cyclin B1 mediates the inhibition of proliferation induced by omega-3 fatty acids in MDA-MB-231 breast cancer cells. Int J Biochem Cell Biol 38, 196-208, 2006.
38. Gonzalez MJ, Schemmel RA, Gray JL, Dugan L Jr, Sheffield LG, et al.: Effect of dietary fat on growth of MCF-7 and MDA-MB-231 human breast carcinomas in athymic nude mice: relationship between carcinoma growth and lipid peroxidation levels. Carcinogenesis 12, 1231-1235, 1991.
39. Hong MY, Bancroft LK, Turner ND, Davidson LA, Murphy ME, et al.: Fish oil decreases oxidative DNA damage by enhancing apoptosis in rat colon, Nutr Cancer 52, 166-175 2005.
40. Tisdale MJ and Beck SA: Inhibition of tumour-induced lipolysis in vitro and cachexia and tumor growth in vivo by eicosapentaenoic acid. Biochem Pharm 41, 103-107, 1991.
41. Price SA and Tisdale MJ: Mechanism of inhibition of a tumor lipid-mobilizing factor by eicosapentaenoic acid. Cancer Res 58, 4827-4831, 1998.