Biosynthesis of thiamin thiazole in eukaryotes: Conversion of NAD to an advanced intermediate

Journal of the American Chemical Society

Volumn 129, Issue 10, 2007, Pages 2914-2922

  Chatterjee, Abhishek ^a   Jurgenson, Christopher T ^a   Schroeder, Frank C ^a   Ealick, Steven E ^a   Begley, Tadhg P ^a  

^a Department of Obstetrics Gynecology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EUKARYOTES; MUTANTS; THIAMIN THIAZOLE;

BIOSYNTHESIS; CATALYSIS; METABOLITES; MUTAGENESIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; YEAST;

ENZYME KINETICS;

1,2 PHENYLENEDIAMINE; 5 (2 HYDROXYETHYL) 4 METHYLTHIAZOLE 2 CARBOXYLIC ACID; COCARBOXYLASE; GLYCINE; MUTANT PROTEIN; NICOTINAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE; QUINOXALINE DERIVATIVE; THIAMINE; THIAZOLE; UNCLASSIFIED DRUG;

ARTICLE; BIOSYNTHESIS; CATALYSIS; ELECTROSPRAY MASS SPECTROMETRY; ENZYME MECHANISM; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN FUNCTION; REACTION ANALYSIS; SACCHAROMYCES CEREVISIAE;

ADENOSINE DIPHOSPHATE; ADENOSINE DIPHOSPHATE RIBOSE; EUKARYOTIC CELLS; NAD; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SUBSTRATE SPECIFICITY; THIAMINE; THIAMINE PYROPHOSPHATE; THIAZOLES;

EID: 33947204418     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja067606t     Document Type: Article

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