Transcription of Bacillus subtilis degR is σD dependent and suppressed by multicopy proB through σD

Journal of Bacteriology

Volumn 178, Issue 1, 1996, Pages 216-222

  Ogura, Mitsuo ^a   Tanaka, Teruo ^a  

^a TOKAI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ENZYME; PEPTIDASE; SIGMA FACTOR;

ARTICLE; BACILLUS SUBTILIS; CONSENSUS SEQUENCE; GENETIC TRANSCRIPTION; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION;

BACILLUS SUBTILIS; BACTERIAL PROTEINS; BASE SEQUENCE; CONSENSUS SEQUENCE; DNA-DIRECTED RNA POLYMERASES; EXOPEPTIDASES; FLAGELLIN; GENE DOSAGE; GENE EXPRESSION REGULATION, BACTERIAL; GENES, BACTERIAL; MOLECULAR SEQUENCE DATA; PEPTIDE HYDROLASES; PHOSPHOTRANSFERASES (CARBOXYL GROUP ACCEPTOR); PROMOTER REGIONS (GENETICS); RECOMBINANT FUSION PROTEINS; RNA, BACTERIAL; RNA, MESSENGER; SIGMA FACTOR; SUPPRESSION, GENETIC; TRANSCRIPTION, GENETIC;

BACILLUS SUBTILIS; BACTERIA (MICROORGANISMS); OCTODON DEGUS;

EID: 0030059640     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/jb.178.1.216-222.1996     Document Type: Article

References (32)

1. Barilla, D., T. Caramori, and A. Galizzi. 1994. Coupling of flagellin gene transcription to flagellar assembly in Bacillus subtilis. J. Bacteriol. 176:4558-4564
2. Dahl, M. K., T. Msadek, F. Kunst, and G. Rapoport. 1991. Mutational analysis of the Bacillus subtilis DegU regulator and its phosphorylation by the DegS protein kinase J. Bacteriol. 173:2539-2547.
3. Dahl, M. K., T. Msadek, F. Kunst, and G. Rapoport. 1992. The phosphorylation state of the DegU response regulator acts as a molecular switch allowing either degradative enzyme synthesis or expression of genetic com petence in Bacillus subtilis. J Biol. Chem. 267:14509-14514.
4. Gilman, M. Z., J. L. Wiggs, and M. J. Chamberlin. 1981 Nucleotide sequence of two Bacillus subtilis promoters used by Bacillus subtilis sigma-28 RNA polymerase Nucleic Acids Res. 9:5991-6000.
5. 28 gene. J. Bacteriol. 170: 1568-1574.
6. Helmann, J. D., L. M. Marquez, V. L. Singer, and M. J. Chamberlin. 1988. Cloning and characterization of the Bacillus subtilis sigma-28 gene, p 189-193 In A T. Ganesan and J. A. Hoch (ed), Genetics and biotechnology of bacilli, vol 2, Academic Press, Inc., Orlando, Fla.
7. Hock, J. A. 1993 spo0 genes, the phosphorelay, and the initiation of sporulation, p. 747-755 In A L Sonenshein, J. A. Hoch, and R. Losick (ed.), Bacillus subtilis and other gram-positive bacteria biochemistry, physiology, and molecular genetics American Society for Microbiology, Washington, D.C.
8. Itaya, M. Unpublished results.
9. Kawamura, F., and R. H. Doi. 1984. Construction of a Bacillus subtilis double mutant deficient in extracellular alkaline and neutral proteases. J. Bacteriol 160:442-444
10. Kunst, F., T. Msadek, and G. Rapoport. 1994. Signal transduction network controlling degradative enzyme synthesis and competence in Bacillus subtilis, p 1-20. In P. J. Piggot, C. P. Moran, Jr , and P Youngman (ed.), Regulation of bacterial differentiation American Society for Microbiology, Washington, D.C.
11. Kuroda, A., and J. Sekiguchi. 1993. High-level transcription of the major Bacillus subtilis autolysin operon depends on expression of the sigma D gene and is affected by a sin (flaD) mutation. J. Bacteriol. 175:795-801.
12. Maniatis, T., E. F. Fritsch, and J. Sambrook. 1982. Molecular cloning, a laboratory manual Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
13. Márquez-Magaña, L. M., and M. J. Chamberlin. 1994. Characterization of the sigD transcription unit of Bacillus subtilis. J. Bacteriol. 176:2427-2434
14. D expression and activity by spo0, abrB, and sin gene products in Bacillus subtilis. J. Bacteriol. 176:2435-2438.
15. 28 form of RNA polymerase. J. Bacteriol. 175: 3095-3101
16. D-dependent operon of Bacillus subtilis. J. Bacteriol. 176:4492-4500.
17. Msadek, T., F. Kunst, and G. Rapoport. 1993. Two-component regulatory systems, p. 729-745 In A. L. Sonenshein, J. A. Hoch, and R. Lobick (ed.), Bacillus subtilis and other gram-positive bacteria: biochemistry, physiology, and molecular genetics. American Society for Microbiology, Washington, D.C.
18. Mukai, K., M. Kawata, and T. Tanaka. 1990. Isolation and phosphorylation of the Bacillus subtilis degS and degU gene products. J. Biol. Chem. 265: 824-834
19. Mukai, K., M. Kawata-Mukai, and T. Tanaka. 1992. Stabilization of phosphorylated Bacillus subtilis DegU by DegR. J Bacteriol. 174:7954-7962.
20. Nagami, Y., and T. Tanaka. 1986. Molecular cloning and nucleotide sequence of a DNA fragment from Bacillus natto that enhances production of extracellular proteases and levansucrase in Bacillus subtilis. J Bacteriol. 166: 20-28.
21. Ogura, M., M. Kawata-Mukai, M. Itaya, K. Takio, and T. Tanaka. 1994. Multiple copies of the proB gene enhance degS-dependent extracellular protease production in Bacillus subtilis. J. Bacteriol. 176:5673-5680.
22. Ogura, M., and T. Tanaka. Unpublished results.
23. Ordal, G. W., L. Màrquez-Magaña, and M. J. Chamberlin. 1993 Motility and chemotaxis, p. 765-784 In A. L. Sonenshein, J. A. Hoch, and R Losick (ed ). Bacillus subtilis and other gram-positive bacteria, biochemistry, physiology, and molecular genetics. American Society for Microbiology, Washington, D.C.
24. Parkinson, J. S. 1993 Signal transduction schemes of bacteria. Cell 73: 857-871.
25. Schaeffer, P. J., J. Millet, and J. Aubert. 1965 Catabolite repression of bacterial sporulation. Proc. Natl. Acad Sci. USA 54:704-711.
26. Shimotsu, H., and D. Henner. 1986. Construction of a single copy integration vector and its use in analysis of regulation of the trp operon of Bacillus subtilis. Gene 33:103-119.
27. Tanaka, T., M. Kawata, and K. Mukai. 1991. Altered phosphorylation of Bacillus subtilis DegU caused by single amino acid changes in DegS. J. Bacteriol. 173:5507-5515.
28. Tanaka, T., M. Kawata, Y. Nagami, and H. Uchiyama. 1987. prtR enhances the mRNA level of the Bacillus subtilis extracellular proteases. J. Bacteriol. 169:3044-3050.
29. Tokunaga, T., M. H. Rashid, A. Kuroda, and J. Sekiguchi. 1994. Effect of degS-degU mutations on the expression of sigD, encoding an alternative sigma factor, and autolysin operon of Bacillus subtilis. J. Bacteriol. 176: 5177-5180
30. Ward, J. B., Jr., and S. A. Zahler. 1973. Genetic studies of leucine biosynthesis in Bacillus subtilis. J. Bacteriol. 116:719-726.
31. Yang, M., H. Shimotsu, E. Ferrari, and D. J. Henner. 1987. Characterization and mapping of the Bacillus subtilis prtR gene. J. Bacteriol. 169:434-437
32. Yanisch-Perron, C., J. Vieira, and J. Messing. 1985. Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors. Gene 33:103-119.