An in vitro model of the leukocyte interactions associated with granuloma formation in Mycobacterium tuberculosis infection

Immunology and Cell Biology

Volumn 85, Issue 2, 2007, Pages 160-168

  Birkness, Kristin A ^a   Guarner, Jeannette ^b   Sable, Suraj B ^a   Tripp, Ralph A ^c   Kellar, Kathryn L ^a   Bartlett, Jeanine ^b   Quinn, Frederick D ^a,c  

^a CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^b CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^c UNIVERSITY OF GEORGIA   (United States)

Author keywords

Granuloma; In vitro model; Mycobacterium tuberculosis

Indexed keywords

CD3 ANTIGEN; CD68 ANTIGEN; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 6; INTERLEUKIN 8; TUBERCULIN; TUMOR NECROSIS FACTOR ALPHA;

ACID FAST BACTERIUM; ADULT; ARTICLE; CELL AGGREGATION; CELL DIFFERENTIATION; CELL INTERACTION; CHEMOTAXIS; CONTROLLED STUDY; EPITHELIOID CELL; GRANULOMA; HUMAN; HUMAN CELL; IN VITRO STUDY; LEUKOCYTE; LYMPHOCYTE; MACROPHAGE; MICROSCOPY; MYCOBACTERIOSIS; MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; NORMAL HUMAN; PATHOLOGY; PERIPHERAL BLOOD MONONUCLEAR CELL; SKIN TEST; SUPERNATANT; TUBERCULOSIS;

ADULT; CELLS, CULTURED; CHEMOTAXIS, LEUKOCYTE; CULTURE MEDIA, CONDITIONED; CYTOKINES; GRANULOMA; HUMANS; LEUKOCYTES; MIDDLE AGED; MODELS, BIOLOGICAL; MYCOBACTERIUM TUBERCULOSIS; TUBERCULOSIS;

BACILLI (CLASS); CORYNEBACTERINEAE; MYCOBACTERIUM TUBERCULOSIS;

EID: 33947189174     PISSN: 08189641     EISSN: 14401711     Source Type: Journal    
DOI: 10.1038/sj.icb.7100019     Document Type: Article

References (49)

1. Flynn JL, Chan J. Immunology of tuberculosis. Annu Rev Immunol 2001; 19: 93-129.
2. Raviglione MC, Snider Jr DE, Kochi A. Global epidemiology of tuberculosis. Morbidity and mortality of a worldwide epidemic. JAMA 1995; 273: 220-226.
3. Rom WN, Schluger N, Law K, Condos R, Zhang Y, Weiden M et al. Human host response to Mycobacterium tuberculosis. Schweiz Med Wochenschr 1995; 125: 2178-2185.
4. Dreher D, Nicod LP. Dendritic cells in the mycobacterial granuloma are involved in acquired immunity. Am J Respir Crit Care Med 2002; 165: 1577-1578.
5. Banchereau J, Briere F, Caux C, Davoust J, Lebecque S, Liu YJ et al. Immunobiology of dendritic cells. Annu Rev Immunol 2000; 18: 767-811.
6. Orme IM, Cooper AM. Cytokine/chemokine cascades in immunity to tuberculosis. Immunol Today 1999; 20: 307-312.
7. Kurashima K, Mukaida N, Fujimura M, Yasui M, Nakazumi Y, Matsuda T et al. Elevated chemokine levels in bronchoalveolar lavage fluid of tuberculosis patients. Am J Respir Crit Care Med 1997; 155: 1474-1477.
8. Schluger NW, Rom WN. The host immune response to tuberculosis. Am J Respir Crit Care Med 1998; 157 (Part 1): 679-691.
9. Kindler V, Sappino AP, Grau GE, Piguet PF, Vassalli P. The inducing role of tumor necrosis factor in the development of bactericidal granulomas during BCG infection. Cell 1989; 56: 731-740.
10. Friedland JS, Remick DG, Shattock R, Griffin GE. Secretion of interleukin-8 following phagocytosis of Mycobacterium tuberculosis by human monocyte cell lines. Eur J Immunol 1992; 22: 1373-1378.
11. Rook GA. Macrophages and Mycobacterium tuberculosis: the key to pathogenesis. Immunol Ser 1994; 60: 249-261.
12. Flynn JL, Goldstein MM, Chan J, Triebold KJ, Pfeffer K, Lowenstein CJ et al. Tumor necrosis factor-alpha is required in the protective immune response against Mycobacterium tuberculosis in mice. Immunity 1995; 2: 561-572.
13. Trinchieri G, Kubin M, Bellone G, Cassatella MA. Cytokine cross-talk between phagocytic cells and lymphocytes: relevance for differentiation/ activation of phagocytic cells and regulation of adaptive immunity. J Cell Biochem 1993; 53: 301-308.
14. Orme IM. The immunopathogenesis of tuberculosis: a new working hypothesis. Trends Microbiol 1998; 6: 94-97.
15. Swaminathan S, Gong J, Zhang M, Samten B, Hanna LE, Narayanan PR et al. Cytokine production in children with tuberculous infection and disease. Clin Infect Dis 1999; 28: 1290-1293.
16. Hirsch CS, Toossi Z, Othieno C, Johnson JL, Schwander SK, Robertson S et al. Depressed T-cell interferon-gamma responses in pulmonary tuberculosis: analysis of underlying mechanisms and modulation with therapy. J Infect Dis 1999; 180: 2069-2073.
17. Toossi Z. Cytokine circuits in tuberculosis. Infect Agents Dis 1996; 5: 98-107.
18. Zhang M, Lin Y, Iyer DV, Gong J, Abrams JS, Barnes PF. T-cell cytokine responses in human infection with Mycobacterium tuberculosis. Infect Immun 1995; 63: 3231-3234.
19. Lemaire I, Yang H, Lafont V, Dornand J, Commes T, Cantin MF. Differential effects of macrophage- and granulocyte-macrophage colony-stimulating factors on cytokine gene expression during rat alveolar macrophage differentiation into multinucleated giant cells (MGC): role for IL-6 in type 2 MGC formation. J Immunol 1996; 157: 5118-5125.
20. Russell DG, Sturgill-Koszycki S, Vanheyningen T, Collins H, Schaible UE. Why intracellular parasitism need not be a degrading experience for Mycobacterium. Philos Trans R Soc Lond B: Biol Sci 1997; 352: 1303-1310.
21. Saunders BM, Frank AA, Orme IM. Granuloma formation is required to contain bacillus growth and delay mortality in mice chronically infected with Mycobacterium tuberculosis. Immunol 1999; 98: 324-328.
22. Raupach B, Kaufmann SH. Immune responses to intracellular bacteria. Curr Opin Immunol 2001; 13: 417-428.
23. Cardona PJ, Llatjos R, Gordillo S, Diaz J, Ojanguren I, Ariza A et al. Evolution of granulomas in lungs of mice infected aerogenically with Mycobacterium tuberculosis. Scand J Immunol 2000; 52: 156-163.
24. McMurray DN, Collins FM, Dannenberg Jr AM, Smith DW. Pathogenesis of experimental tuberculosis in animal models. Curr Top Microbiol Immunol 1996; 215: 157-179.
25. Smith DW, Wiegeshaus EH. What animal models can teach us about the pathogenesis of tuberculosis in humans. Rev Infect Dis 1989; 11 (Suppl 2): S385-S393.
26. Clark-Curtiss JE. Identification of virulence determinants in pathogenic mycobacteria. Curr Top Microbiol Immunol 1998; 225: 57-79.
27. Shikama Y, Kobayashi K, Kasahara K, Kaga S, Hashimoto M, Yoneya I et al. Granuloma formation by artificial microparticles in vitro. Macrophages and monokines play a critical role in granuloma formation. Am J Pathol 1989; 134: 1189-1199.
28. Doughty BL, Phillips SM. Delayed hypersensitivity granuloma formation around Schistosoma mansoni eggs in vitro. I. Definition of the model. J Immunol 1982; 128: 30-36.
29. Chensue SW, Warmington K, Ruth J, Lincoln P, Kuo MC, Kunkel SL. Cytokine responses during mycobacterial and schistosomal antigen- induced pulmonary granuloma formation. Production of Th1 and Th2 cytokines and relative contribution of tumor necrosis factor. Am J Pathol 1994; 145: 1105-1113.
30. Chensue SW, Warmington KS, Ruth JH, Lincoln P, Kunkel SL. Cytokine function during mycobacterial and schistosomal antigen- induced pulmonary granuloma formation. Local and regional participation of IFN-gamma, IL-10, and TNF. J Immunol 1995; 154: 5969-5976.
31. Puissegur MP, Botanch C, Duteyrat JL, Delsol G, Caratero C, Altare F. An in vitro dual model of mycobacterial granulomas to investigate the molecular interactions between mycobacteria and human host cells. Cell Microbiol 2004; 6: 423-433.
32. Seitzer U, Gerdes J. Generation and characterization of multicellular heterospheroids formed by human peripheral blood mononuclear cells. Cells Tissues Organs 2003; 174: 110-116.
33. Birkness KA, Swords WE, Huang PH, White EH, Dezzutti CS, Lal RB et al. Observed differences in virulence-associated phenotypes between a human clinical isolate and a veterinary isolate of Mycobacterium avium. Infect Immun 1999; 67: 4895-4901.
34. Birkness KA, Deslauriers M, Bartlett JH, White EH, King CH, Quinn FD. An in vitro tissue culture bilayer model to examine early events in Mycobacterium tuberculosis infection. Infect Immun 1999; 67: 653-658.
35. Macatonia SE, Hosken NA, Litton M, Vieira P, Hsieh CS, Culpepper JA et al. Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells. J Immunol 1995; 154: 5071-5079.
36. Kellar KL, Kalwar RR, Dubois KA, Crouse D, Chafin WD, Kane BE. Multiplexed fluorescent bead-based immunoassays for quantitation of human cytokines in serum and culture supernatants. Cytometry 2001; 45: 27-36.
37. Postlethwaite AE, Jackson BK, Beachey EH, Kang AH. Formation of multinucleated giant cells from human monocyte precursors. Mediation by a soluble protein from antigen-and mitogen-stimulated lymphocytes. J Exp Med 1982; 155: 168-178.
38. Byrd TF. Multinucleated giant cell formation induced by IFN-gamma/IL-3 is associated with restriction of virulent Mycobacterium tuberculosis cell to cell invasion in human monocyte monolayers. Cell Immunol 1998; 188: 89-96.
39. Davies PDO (ed.) Clinical Tuberculosis, 2nd edn. Chapman & Hall Medical: London, 1998.
40. Bergeron A, Bonay M, Kambouchner M, Lecossier D, Riquet M, Soler P et al. A. Cytokine patterns in tuberculous and sarcoid granulomas: correlations with histopathologic features of the granulomatous response. J Immunol 1997; 159: 3034-3043.
41. Schauf V, Rom WN, Smith KA, Sampalo EP, Meyn PA, Tramontana JM et al. Cytokine gene activation and modified responsiveness to interleukin-2 in the blood of tuberculosis patients. J Infect Dis 1993; 168: 1056-1059.
42. Law K, Weiden M, Harkin T, Tchou-Wong K, Chi C, Rom WN. Increased release of interleukin-1 beta, interleukin-6, and tumor necrosis factor-alpha by bronchoalveolar cells lavaged from involved sites in pulmonary tuberculosis. Am J Respir Crit Care Med 1996; 153: 799-804.
43. Tsao TC, Hong J, Huang C, Yang P, Liao SK, Chang KS. Increased TNF-alpha, IL-1 beta and IL-6 levels in the bronchoalveolar lavage fluid with the upregulation of their mRNA in macrophages lavaged from patients with active pulmonary tuberculosis. Tuber Lung Dis 1999; 79: 279-285.
44. Goldsby RA, Kindt TJ, Osborne BA. Kuby Immunology, 4th edn. W. H. Freeman and Company: New York, 2000.
45. Lukacs NW, Chensue SW, Strieter RM, Warmington K, Kunkel SL. Inflammatory granuloma formation is mediated by TNF-alpha- inducible intercellular adhesion molecule-1. J Immunol 1994; 152: 5883-5889.
46. Beltan E, Horgen L, Rastogi N. Secretion of cytokines by human macrophages upon infection by pathogenic and non-pathogenic mycobacteria. Microb Pathog 2000; 28: 313-318.
47. Fenton MJ, Vermeulen MW. Immunopathology of tuberculosis: roles of macrophages and monocytes. Infect Immun 1996; 64: 683-690.
48. Ben-Baruch A, Michiel DF, Oppenheim JJ. Signals and receptors involved in recruitment of inflammatory cells. J Biol Chem 1995; 270: 11703-11706.
49. Nau GJ, Guilfoile P, Chupp GL, Berman JS, Kim SJ, Kornfeld H et al. A chemoattractant cytokine associated with granulomas in tuberculosis and silicosis. Proc Natl Acad Sci USA 1997; 94: 6414-6419.