Effect of angiotensin II on α1-adrenoceptor-mediated inotropic response of heart in different-age rats

Chinese Journal of Pharmacology and Toxicology

Volumn 21, Issue 1, 2007, Pages 7-10

  Shi, Shu Tian ^a   Li, Yan Fang ^a   Li, Jun ^b   Long, Chao Liang ^b   Li, Xing ^b   Wang, Hai ^b  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

Author keywords

Age factors; Heart atrium; Receptors, adrenergic, ; Receptors, angiotensin

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR; ANGIOTENSIN II; PHENYLEPHRINE;

AGE DISTRIBUTION; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; HEART ATRIUM; HEART MUSCLE; INOTROPISM; NONHUMAN; RAT;

RATTUS; RATTUS NORVEGICUS;

EID: 33947167668     PISSN: 10003002     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. 1-adrenoceptor subtypes in rat heart[J]. Chin J Pharmacol Toxicol, 1996, 10(4):281-284.
2. Zhang YZ, Zhang YY, Chen MZ, Han QD. Beta-adrenoceptors potentiate alpha1-adrenoceptor-mediated inotropic response in rat left atria[J]. Acta Pharmacol Sin, 2004, 25(1):29-34.
3. Qian JQ. The pharmacology of renin angiotensin[M] // Yang ZC. Medical Pharmacology. 4th ed. Beijing; People' s Medical Publishing House, 2004:483-502.
4. Li YF, Li JL, Hu YX, Li DY, Wang L, Mu SC. Effects of angiotensin II on the action of β-adrenoceptor stimulated by isoprenalin in Sprague-Dawley rats[J]. Chin J Geriatr, 2002, 21(5):350-353.
5. 1- adrenergic receptors[J]. Chin Pharmacol Bull, 1994, 10(6):411-414.
6. 1-adrenoceptor subtypes between 12-month old and 3-month old Wistar rats[J]. Chin J Pharmacol Toxicol, 1998, 12(2):101-104.
7. Puceat M, Clement-Chomienne O, Terzic A, Vassort G. Alpha1-adrenoceptor and purinoceptor agonists modulate Na-H antiport in single cardiac cells[J]. Am J Physiol, 1993, 264(2 Pt 2):H310-H319.
8. Montagne O, Le Corvoisier P, Guenoun T, Laplace M, Crozatier B. Impaired alpha1-adrenergic responses in aged rat hearts[J]. Fundam Clin Pharmacol, 2005, 19(3):331-339.
9. + exchange: structure, regulation, and its role in heart disease[J]. Circ Res, 1999, 85(9):777-786.
10. Tsutsumi K, Stromberg C, Viswanathan M, Saavedra JM. Angiotensin-II receptor subtypes in fetal tissue of the rat: autoradiography, guanine nucleotide sensitivity, and association with phosphoinositide hydrolysis[J]. Endocrinology, 1991, 129(2):1075-1082.
11. Heymes C, Silvestre JS, Llorens-Cortes C, Chevalier B, Marotte F, Levy BI, et al. Cardiac senescence is associated with enhanced expression of angiotensin II receptor subtypes[J]. Endocrinology, 1998, 139(5):2579-2587.
12. Shivakumar K, Dostal DE, Boheler K, Baker KM, Lakatta EG. Differential response of cardiac fibroblasts from young adult and senescent rats to ANG II [J]. Am J Physiol Heart Circ Physiol, 2003, 284(4):H1454-H1459.
13. Heymes C, Swynghedauw B, Chevalier B. Activation of angiotensinogen and angiotensin-converting enzyme gene expression in the left ventricle of senescent rats [J]. Circulation, 1994, 90(3):1328-1333.
14. Thompson MM, Oyama TT, Kelly FJ, Kennefick TM, Anderson S. Activity and responsiveness of the renin-angiotensin system in the aging rat[J]. Am J Physiol Regul Integr Comp Physiol, 2000, 279(5):R1787-R1794.