β-adrenoceptors potentiate α1-adrenoceptor-mediated inotropic response in rat left atria

Acta Pharmacologica Sinica

Volumn 25, Issue 1, 2004, Pages 29-34

  Zhang, Yong Zhen ^a   Zhang, You Yi ^a   Chen, Ming Zhe ^a   Han, Qi De ^a  

^a NONE

Author keywords

Adrenergic agonists; Adrenergic receptor antagonists; Alpha 1 adrenergic receptors; Beta adrenergic receptors; Cardiac inotropism; Heart atrium; Inositol phosphates

Indexed keywords

3 ISOPROPYLAMINO 1 (7 METHYL 4 INDANYLOXY) 2 BUTANOL; 4 (3 TERT BUTYLAMINO 2 HYDROXYPROPOXY) 2 BENZIMIDAZOLONE; ADRENERGIC RECEPTOR BLOCKING AGENT; ADRENERGIC RECEPTOR STIMULATING AGENT; ALPHA 1 ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR; INOSITOL PHOSPHATE; ISOPRENALINE; NORADRENALIN; PHENTOLAMINE; PHENYLEPHRINE; PRAZOSIN; PROPRANOLOL;

ANIMAL TISSUE; ARTICLE; COLUMN CHROMATOGRAPHY; CONCENTRATION RESPONSE; HEART CONTRACTION; HEART FUNCTION; HEART LEFT ATRIUM; INOTROPISM; MALE; NONHUMAN; RAT;

ADRENERGIC BETA-ANTAGONISTS; ANIMALS; ATRIAL FUNCTION, LEFT; HEART VENTRICLES; INOSITOL PHOSPHATES; MALE; MYOCARDIAL CONTRACTION; NOREPINEPHRINE; PHENYLEPHRINE; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC, ALPHA-1; RECEPTORS, ADRENERGIC, BETA; STIMULATION, CHEMICAL;

EID: 0345763137     PISSN: 16714083     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. 1- and β -adrenoceptors stimulation to the inotropic response. Basic Res Cardiol 1989; 84 Suppl: 9-17.
2. 1-adrenoceptor-mediated inhibition of cellular cAMP accumulation in neonatal rat ventricular myocytes. Naunyn Schmiedebergs Arch Pharmacol 1993; 347: 384-93.
3. 1-adrenoceptor subtypes on β-adrenoceptor-mediated positive inotropic response in rat left atria. Acta Physiol Sin 1999; 46: 473-9.
4. 1-adrenoceptor on β-adrenoceptor-induced positive inotropic response in the rat with cardiac insufficiency. Chin J Pathophysiol 1995; 11: 567-71.
5. Skomedal T, Schiander IG, Osnes JB. Both alpha and beta adrenoceptor-mediated components contribute to final inotropic response to norepinephrine in rat heart. J Pharmacol Exp Ther 1988; 247: 1204-10.
6. Curiel R, Perez-Gonzalez J, Brito N, Zerpa R, Tellez D, Cabrera J, et al. Positive inotropic effects mediated by alpha 1 adrenoceptors in intact human subjects. J Cardiovasc Pharmacol 1989; 14: 603-15.
7. 1-adrenoceptor stimulation: study in isolated perfused rat heart. J Pharm Pharmacol 2001; 53: 233-42.
8. Schäfer M, Pönicke K, Heinroth-Hoffmann I, Brodde OE, Piper HM, Schlüter KD. Beta-adrenoceptor stimulation attenuates the hypertrophic effect of alpha-adrenoceptor stimulation in adult rat ventricular cardiomyocytes. J Am Coll Cardiol 2001; 37: 300-7.
9. 1B-adrenoceptors in phenylephrine-induced positive inotropic response in isolated rat left atrium. J Cardiovasc Pharmacol 1994; 24: 745-52.
10. 1-adrenoceptor: inotropic effect and physiologic and pathologic implication. Life Sci 1997; 60: 1305-18.
11. Viko H, Sandnes D, Skomedal T, Osnes JB. Effect of concomitant beta-adrenoceptor stimulation on alpha1-adrenoceptor-mediated increase of inositol-1,4,5-trisphosphate mass in adult rat cardiomyocytes. Pharmacol Toxicol 1998; 83: 23-8.