Association of C1019T polymorphism in the connexin37 gene and coronary artery disease in Chinese Han population

National Medical Journal of China

Volumn 87, Issue 2, 2007, Pages 100-104

  Han, Ya Ling ^a   Xi, Su Ya ^a   Zhang, Xiao Lin ^a   Yan, Cheng Hui ^a   Yang, Yong ^a   Kang, Jian ^a  

^a GENERAL HOSPITAL OF NORTHERN THEATER COMMAND   (China)

Author keywords

Connexin37; Coronary artery disease; Polymorphism

Indexed keywords

CHOLESTEROL; CONNEXIN 37; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ADULT; AGED; ANGIOCARDIOGRAPHY; ANGIOGRAPHY; ARTICLE; ATHEROSCLEROSIS; CHINESE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DNA POLYMORPHISM; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENOTYPE; HOMOZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; MALE; PATHOPHYSIOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; POPULATION GENETICS; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK FACTOR; SEX DIFFERENCE; TRIACYLGLYCEROL BLOOD LEVEL;

ADULT; AGED; ALLELES; BASE SEQUENCE; CHINA; CONNEXINS; CORONARY ARTERY DISEASE; DNA MUTATIONAL ANALYSIS; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; LOGISTIC MODELS; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS;

EID: 33947164708     PISSN: 03762491     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Winkelmann BR, Hager J. Genetic variation in coronary heart disease and myocardial infarction: methodological overview and clinical evidence. Pharmacogenomics, 2000,1:73-94.
2. Chinese source.
3. Li JJ. Inflammation: an important mechanism for different clinical entities of coronary artery diseases. Chin Med J, 2005, 118: 1817-1826.
4. HU D. Cardiology in new millennium: what will the 21st century bring. Chin Med J, 2000,113:3-4.
5. Boerma M, Forsberg L, Van Zeijl L, et al. A genetic polymorphism in connexin 37 as a prognostic marker for atherosclerotic plaque development. J Intern Med, 1999, 246: 211-218.
6. Yeh HI, Chou Y, Liu HF, et al. Connexin37 gene polymorphism and coronary artery disease in Taiwan. Int J Cardiol, 2001,81: 251-255.
7. Wong CW, Christen T, Pfenniger A, et al. Do allelic variants of the connexin37 1019 gene polymorphism differentially predict for coronary artery disease and myocardial infarction? Atherosclerosis, 2006,1-7.
8. Listi F, Candore G, Lio D, et al. Association between C1019T polymorphism of connexin37 and acute myocardial infarction: a study in patients from Sicily. Int J Cardiol, 2005,102:269-271.
9. Yamada Y, Izawa H, Ichihara S, et al. Prediction of the risk of myocardial infarction from polymorphisms in candidate genes. N Engl J Med, 2002,347:1916-1923.
10. Yamada Y, Ichihara S, Izawa H, et al. Genetic risk for coronary artery disease in individuals with or without type 2 diabetes. Mol Genet Metab, 2004,81:282-290.
11. Hirashiki A, Yamada Y, Murase Y, et al. Association of gene polymorphisms with coronary artery disease in low- or high-risk subjects defined by conventional risk factors. J Am Coll Cardiol, 2003,42:1429-1437.
12. Austen WG, Edwards JE, Faye RL, et al. A reporting system on patients evaluated for coronary artery disease, report of the Ad Hoc committee for grading of coronary artery disease, council on cardiovascular surgery, American Heart Association. Circulation, 1975,51:5-40.
13. Van Camp G, Coucke P, Speleman F, et al. The gene for human gap junction protein connexin37 (GJA4) maps to chromosome 1p35.1, in the vicinity of D1S195. Genomics, 1995, 30: 402-403.
14. Reed KE, Westphale EM, Larson DM, et al. Molecular cloning and functional expression of human connexin37, an endothelial cell gap junction protein. J Clin Invest, 1993,91:997-1004.
15. Yeh HI, Rothery SD upont R, et al. Individual gap junction plaques contain multiple connexins in arterial endothelium. Circ Res, 1998,83:1248-1263.
16. Yeh HI, Lxi YJ, Chang HM, et al. Multiple connexin expression in regenerating arterial endothelial gap junctions. Arterioscler Thromb Vasc Biol, 2000,20:1753-1762.
17. Wong CW, Christen T, Foglia B, et al. Eliminating connexin37 enhances atherosclerosis in apolipoprotein E-deficient mice. Circulation,2004,110:III-38/39.
18. Wang Q, Rao S, Shin GQ, et al. Premature myocardial infarction novel susceptibility locus on chromosome 1P34-36 identified by genomewide linkage analysis. Am J Hum Genet, 2004, 74: 262-271.
19. Cooper CD, Solan JL, Dolejsi MK, et al. Analysis of connexin phosphorylation sites. Method, 2000,20:196-204.