Radiosynthesis of 3-(3-[18F]fluoropropoxy)-4-(benzyloxy)-N-[(1- dimethylaminocyclopentyl)methyl]-5-methoxybenzamide, a potential PET radiotracer for the glycine transporter GlyT-2

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 49, Issue 14, 2006, Pages 1247-1258

  Tian, Haibin ^a   Vogel, Rebecca ^a   Amici, Louis ^a   Tamagnan, Gilles ^a   Baldwin, Ronald M ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Fluorine 18; Glycine transporter 2(GlyT2); PET; Radiotracer transporter 2(GlyT2)

Indexed keywords

AMIDES; FLUORINE; POTASH; RADIOACTIVE TRACERS; SOLVENT EXTRACTION; SULFUR COMPOUNDS;

BENZAMIDES; FLUORINE-18; GLYCINE TRANSPORTER 2; IN-VIVO; ONE POT; PET RADIOLIGAND; RADIOSYNTHESIS; RADIOTRACER TRANSPORTER 2(GLYCINE TRANSPORTER 2); SYNTHESISED; TWO STEP METHOD;

AMINO ACIDS;

1,3 PROPANEDIOL DI 4 TOSYLATE; 3 (3 FLUOROPROPOXY) 4 (BENZYLOXY) N [(DIMETHYLAMINOCYCLOPENTYL)METHYL] 5 METHOXYBENZAMIDE F 18; 3 FLUOROPROPYL TOSYLATE F 18; 4 (BENZYLOXY) N [(DIMETHYLAMINOCYCLOPENTYL)METHYL] 5 METHOXYBENZAMIDE F 18; FLUORINE 18; GLYCINE TRANSPORTER 2; GLYCINE TRANSPORTER 2 ANTAGONIST; TOLUENESULFONIC ACID DERIVATIVE; TRACER; UNCLASSIFIED DRUG;

ARTICLE; COMPUTER ASSISTED EMISSION TOMOGRAPHY; DRUG STRUCTURE; DRUG SYNTHESIS; FLUORINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VIVO STUDY; RADIOCHEMISTRY;

EID: 33947120353     PISSN: 03624803     EISSN: 10991344     Source Type: Journal    
DOI: 10.1002/jlcr.1145     Document Type: Article

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