Improved industrial fermentation of lincomycin by phosphorus feeding

Process Biochemistry

Volumn 42, Issue 4, 2007, Pages 662-668

  Li, Xiao Bing ^a,b   Zhao, Guang Rong ^a   Zheng, Hui ^a   Yuan, Ying Jin ^a  

^a TIANJIN UNIVERSITY   (China)

^b North China Pharmaceutical Corporation   (China)

Author keywords

Feeding; Industrial fermentation; Lincomycin; Phosphorus limitation; Productivity

Indexed keywords

CONCENTRATION (PROCESS); FEEDING; FERMENTATION; GROWTH KINETICS; PHOSPHORUS; PRODUCTIVITY;

FERMENTATION SYSTEMS; INDUSTRIAL FERMENTATION; LINCOMYCIN; PHOSPHORUS LIMITATION;

BACTERIA;

EID: 33947109556     PISSN: 13595113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.procbio.2006.12.007     Document Type: Article

References (27)

1. Spizek J., and Rezanka T. Lincomycin, clindamycin and their applications. Appl Microbiol Biotechnol 64 (2004) 455-464
2. Kuo M.S., Yurek D.A., Coats J.H., Chung S.T., and Li G.P. Isolation and identification of 3-propylidene-delta 1-pyrroline-5-carboxylic acid, a biosynthetic precursor of lincomycin. J Antibiot (Tokyo) 45 (1992) 1773-1777
3. Spizek J., and Rezanka T. Lincomycin, cultivation of producing strains and biosynthesis. Appl Microbiol Biotechnol 63 (2004) 510-519
4. Semenova L.E., Sherstobitova T.S., and Gorokhova I.B. The development of a technology for lincomycin biosynthesis with batch-type feeding the substrates during the process. Antibiot Khimioter 39 (1994) 3-8
5. Choi D., and Cho K. Effect of carbon source consumption rate on lincomycin production from Streptomyces lincolnensis. J Microbiol Biotechnol 14 3 (2004) 532-539
6. Young M.D., Kempe L.L., and Bader F.G. Effects of phosphate, glucose and ammonium on cell growth and lincomycin production by streptomyces lincolnensis in chemically defined media. Biotechnol Bioeng 27 (1985) 327-333
7. Sanchez S., and Demain A.L. Metabolic regulation of fermentation processes. Enzyme Microb Technol 31 (2002) 895-906
8. Xiong Z.G. Principles of fermentation technology. The medicinal science and technology (2000), Press of China, Beijing p. 72
9. Teixeira de Mattos M.J., and Neijssel O.M. Bioenergetic consequences of microbial adaptation to low-nutrient environments. J Biotechnol 59 (1997) 117-126
10. Tavares J.M., Duarte L.C., Amaral-Collaco M.T., and Girio F.M. Phosphate limitation stress induces xylitol overproduction by Debaryomyces hansenii. FEMS Microbiol Lett 171 (1999) 115-120
11. Terpstra M. Patent survey on process biochemistry: An improved fermentation process. Process Biochem 40 (2005) 2567-2571
12. Peschke U., Schmidt H., Zhang H.Z., and Piepersberg W. Molecular characterization of the lincomycin-production gene cluster of Streptomyces lincolnensis 78-11. Mol Microbiol 16 (1995) 1137-1156
13. Thorson J.S., Lo S.F., Liu H.W., and Hutchinson C.R. Biosynthesis of 3,6-dideoxyhexoses: new mechanistic reflections upon 2,6-dideoxy, 4,6-dideoxy, and amino sugar construction. J Am Chem Soc 115 (1993) 6963-6994
14. Li J.W., Xiao N.G., and Yu R.Y. Principles and methodologies for biochemical experiments (2000), Peking University Press, Beijing p. 270-3
15. Manuela J.D. Determination of phosphorus in dairy products by sample wet digestion in a microwave oven. Anal Chim Acta 309 (1995) 355-359
16. Zhu L.Y. Study on the aeration conditions of lincomycin fermentation. Chin J Antibiot 26 (2001) 393-394
17. The United States Pharmacopeia 25. United States Pharmacopeial Convention, Rockville, MD; 2002, p. 1007-8.
18. Liu Y.Q., Liu D.H., Su Q., Liu J.R., and Xie D.M. Effects of phosphorus and nitrogen limitations on continuous production of glycerol in a multistage cascade bioreactor by Candida krusei. Biochem Eng J 15 (2003) 101-106
19. Haydock A.K., Porat I., Whitman W.B., and Leigh J.A. Continuous culture of Methanococcus maripaludis under defined nutrient conditions. FEMS Microbiol Lett 238 1 (2004) 85-91
20. Naeimpoor F., and Mavituna F. Metabolic flux analysis in Streptomyces coelicolor under various nutrient limitations. Metab Eng 2 (2000) 140-148
21. Heldal M., Norland S., and Tumyr O. X-ray microanalytic method for measurement of dry matter and elemental content of individual bacteria. Appl Environ Microbiol 50 (1985) 1251-1257
22. Dokmetzian D.A., and Ranalli M.E. Growth in species of the genus Ascobolus. II (Pezizales-Ascomycota). Rev Iberoam Micol 21 2 (2004) 96-99
23. Schrickx J.M., Krave A.S., Verdoes J.C., van den Hondel C.A., Stouthamer A.H., and van Verseveld H.W. Growth and product formation in chemostat and recycling cultures by Aspergillus niger N402 and a glucoamylase overproducing transformant, provided with multiple copies of the glaA gene. J Gen Microbiol. 139 11 (1993) 2801-2810
24. Haq I.U., Ali S., and Qadeer M.A. Influence of dissolved oxygen concentration on intracellular pH for regulation of Aspergillus niger growth rate during citric acid fermentation in a stirred tank bioreactor. Int J Biol Sci 1 (2005) 34-41
25. Richter S., Nieveler J., Schulze H., Bachmann T.T., and Schmid R.D. High yield production of a mutant Nippostrongylus brasiliensis acetylcholinesterase in Pichia pastoris and its purification. Biotechnol Bioeng 93 (2005) 1017-1022
26. Bhargava S., Wenger K.S., and Marten M.R. Pulsed feeding during fed-batch Aspergillus oryzae fermentation leads to improved oxygen mass transfer. Biotechnol Prog 19 (2003) 1091-1094
27. Beuse M., Kopmann A., Diekmann H., and Thoma M. Oxygen, pH value, and carbon source induced changes of the mode of oscillation in synchronous continuous culture of Saccharomyces cerevisiae. Biotechnol Bioeng 63 (1999) 410-417