Novel system uses probasin-based promoter, transcriptional silencers and amplification loop to induce high-level prostate expression

BMC Biotechnology

Volumn 7, Issue , 2007, Pages

  Woraratanadharm, Jan ^a   Rubinchik, Semyon ^a   Yu, Hong ^a   Dong, John Y ^a,b  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b GenPhar Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CANCER CELLS; GENE THERAPY; PROSTATE; PROSTATE CANCER; PROSTATE CELLS;

CELLS; CYTOTOXICITY; GENE EXPRESSION; GENES;

ONCOLOGY;

ADENOVIRUS VECTOR; FAS LIGAND; GREEN FLUORESCENT PROTEIN; PLASMID VECTOR; PROBASIN; TETRACYCLINE;

ADENOVIRUS; ANIMAL CELL; ARTICLE; CANCER GENE THERAPY; CELL STRAIN HEK293; CELL STRAIN LNCAP; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; GENE ACTIVATION; GENE AMPLIFICATION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE EXPRESSION SYSTEM; GENE REPRESSION; GENE TARGETING; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; MOUSE; NONHUMAN; PROMOTER REGION; PROSTATE CANCER; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; SILENCER ELEMENT; SILENCER GENE; SUICIDE GENE THERAPY; TRANSGENE; VIRAL GENE DELIVERY SYSTEM;

ANDROGEN-BINDING PROTEIN; CELL LINE, TUMOR; FEEDBACK; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; GENE TARGETING; GENETIC THERAPY; HUMANS; MALE; NEOPLASM PROTEINS; NUCLEIC ACID AMPLIFICATION TECHNIQUES; PROMOTER REGIONS, GENETIC; PROSTATIC NEOPLASMS; PROTEIN ENGINEERING; TRANSCRIPTION FACTORS;

EID: 33847780079     PISSN: None     EISSN: 14726750     Source Type: Journal    
DOI: 10.1186/1472-6750-7-9     Document Type: Article

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