Enhanced proliferation of astrocytes from β2-adrenergic receptor knockout mice is influenced by the IGF system

Journal of Neurochemistry

Volumn 100, Issue 6, 2007, Pages 1555-1564

  Chesik, Daniel ^a   Glazenburg, Lisa ^a   De Keyser, Jacques ^a   Wilczak, Nadine ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Adrenergic receptors; Astrocytes; IGF binding proteins; Insulin like growth factor; Multiple sclerosis; Proliferation

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR; GLIAL FIBRILLARY ACIDIC PROTEIN; SOMATOMEDIN BINDING PROTEIN; SOMATOMEDIN BINDING PROTEIN 1; SOMATOMEDIN BINDING PROTEIN 2; SOMATOMEDIN BINDING PROTEIN 4; SOMATOMEDIN RECEPTOR;

ADRENERGIC NERVE CELL; ANIMAL CELL; ARTICLE; ASTROCYTE; ASTROCYTOSIS; CELL DISRUPTION; CELL PROLIFERATION; CONTROLLED STUDY; FLUORESCENCE ACTIVATED CELL SORTING; GENE CONTROL; GENE DELETION; KNOCKOUT MOUSE; MITOGENESIS; MOUSE; MULTIPLE SCLEROSIS; NEWBORN; NEWBORN PERIOD; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS REGULATION; RECEPTOR INTRINSIC ACTIVITY; WILD TYPE;

ANIMALS; ANIMALS, NEWBORN; ASTROCYTES; CELL COUNT; CELL PROLIFERATION; CELLS, CULTURED; CEREBRAL CORTEX; CULTURE MEDIA, CONDITIONED; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 1; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 4; MICE; MICE, KNOCKOUT; RECEPTOR, IGF TYPE 1; RECEPTOR, IGF TYPE 2; RECEPTORS, ADRENERGIC, BETA-2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

MUS;

EID: 33847707009     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2006.04289.x     Document Type: Article

References (41)

1. Baltensperger K., Karoor V., Paul H., Ruoho A., Czech M. P. and Malbon C. C. (1996) The beta-adrenergic receptor is a substrate for the insulin receptor tyrosine kinase. J. Biol. Chem. 271, 1061-1064.
2. Bayatti N. and Engele J. (2001) Cyclic AMP modulates the response of central nervous system glia to fibroblast growth factor-2 by redirecting signalling pathways. J. Neurochem. 78, 972-980.
3. Chesik D., Kuhl N. M., Wilczak N. and De Keyser J. (2004a) Enhanced production and proteolytic degradation of insulin-like growth factor binding protein-2 in proliferating rat astrocytes. J. Neurosci. Res. 77, 354-362.
4. Chesik D., Wilczak N. and De Keyser J. (2004b) Insulin-like growth factor binding protein-4 interacts with centrosomes and microtubules in primary astrocytes. Neuroscience 125, 381-390.
5. Chruscinski A. J., Rohrer D. K., Schauble E., Desai K. H., Bernstein D. and Kobilka B. K. (1999) Targeted disruption of the β2 adrenergic receptor gene. J. Biol. Chem. 274, 16 694-16 700.
6. Cook S. J. and McCormick F. (1993) Inhibition by cAMP of Ras-dependent activation of Raf. Science 262, 1069-1072.
7. Dalle S., Imamura T., Rose D. W., Worrall D. S., Ugi S., Hupfeld C. J. and Olefsky J. M. (2002) Insulin induces heterologous desensitization of G-protein-coupled receptor and insulin-like growth factor I signaling by down-regulating β-arrestin-1. Mol. Cell Biol. 22, 6272-6285.
8. Daub H., Weiss F. U., Wallasch C. and Ullrich A. (1996) Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors. Nature 379, 557-560.
9. De Keyser J., Wilczak N., Leta R. and Streetland C. (1999) Astrocytes in multiple sclerosis lack β2 adrenergic receptors. Neurology 53, 1628-1633.
10. De Keyser J., Zeinstra E., Mostert J. and Wilczak N. (2004a) β2-Adrenoceptor involvement in inflammatory demyelination and axonal degeneration in multiple sclerosis. Trends Pharmacol. Sci. 25, 67-71.
11. De Keyser J., Zeinstra E. and Wilczak N. (2004b) Astrocytic β2-adrenergic receptors and multiple sclerosis. Neurobiol. Dis. 15, 331-339.
12. Eng L. F. and Ghirnikar R. S. (1994) GFAP and astrogliosis. Brain Pathol. 4, 229-237.
13. Fahrig T. (1993) Receptor subtype involved and mechanism of norepinephrine-induced stimulation of glutamate uptake into primary cultures of rat brain astrocytes. Glia 7, 212-218.
14. Fawcett J. W. and Asher R. A. (1999) The glial scar and central nervous system repair. Brain Res. Bull. 49, 377-391.
15. Feinstein D. L., Heneka M. T., Gavrilyuk V., Dello Russo C., Weinberg G. and Galea E. (2002) Noradrenergic regulation of inflammatory gene expression in brain. Neurochem. Int. 41, 357-365.
16. Fillenz M., Lowry J. P., Boutelle M. G. and Fray A. E. (1999) The role of astrocytes and noradrenaline in neuronal glucose metabolism. Acta Physiol. Scand. 167, 275-284.
17. Fok-Seang J., Mathews G. A., ffrench-Constant C., Trotter J. and Fawcett J. W. (1995) Migration of oligodendrocyte precursors on astrocytes and meningal cells. Dev. Biol. 171, 1-15.
18. Gutkind J. S. (1998) Cell growth control by G protein-coupled receptors: from signal transduction to signal integration. Oncogene 17, 1331-1342.
19. Hadcock J. R., Port J. D., Gelman M. S. and Malbon C. C. (1992) Crosstalk between tyrosine kinase and G-protein-linked receptors. Phosphorylation of β2-adrenergic receptors in response to insulin. J. Biol. Chem. 267, 26 017-26 022.
20. Hansson E. and Ronnback L. (1992) Adrenergic receptor regulation of amino acid neurotransmitter uptake in astrocytes. Brain Res. Bull. 29, 297-301.
21. Howe L. R., Leevers S. J., Gomez N., Nakielny S., Cohen P. and Marshall C. J. (1992) Activation of the MAP kinase pathway by the protein kinase raf. Cell 71, 335-342.
22. Iacobas D. A., Scemes E. and Spray D. C. (2004) Gene expression alterations in connexin null mice extend beyond the gap junction. Neurochem. Int. 45, 243-250.
23. Jones J. I. and Clemmons D. R. (1995) Insulin-like growth factors and their binding proteins: biological actions. Endocr. Rev. 16, 3-34.
24. Karoor V. and Malbon C. C. (1996) Insulin-like growth factor receptor-1 stimulates phosphorylation of the β2-adrenergic receptor in vivo on sites distinct from those phosphorylated in response to insulin. J. Biol. Chem. 271, 29 347-29 352.
25. Kurino M., Fukunaga K., Ushio Y. and Miyamoto E. (1996) Cyclic AMP inhibits activation of mitogen-activated protein kinase and cell proliferation in response to growth factors in cultured rat cortical astrocytes. J. Neurochem. 67, 2246-2255.
26. Levitzki A. and Gazit A. (1995) Tyrosine kinase inhibition: an approach to drug development. Science 267, 1782-1788.
27. Linseman D. A., Benjamin C. W. and Jones D. A. (1995) Convergence of angiotensin II and platelet-derived growth factor receptor signaling cascades in vascular smooth muscle cells. J. Biol. Chem. 270, 12 563-12 568.
28. Liu X. J., Malkowski M., Guo Y., Erickson G. F., Shimasaki S. and Ling N. (1993) Development of specific antibodies to rat insulin-like growth factor-binding proteins (IGFBP-2 to-6): analysis of IGFBP production by rat granulosa cells. Endocrinology 132, 1176-1183.
29. Mantyh P. W., Rogers S. D., Allen C. J., Catton M. D., Ghilardi J. R., Levin L. A., Maggio J. E. and Vigna S. R. (1995) Beta 2-adrenergic receptors are expressed by glia in vivo in the normal and injured central nervous system in the rat, rabbit, and human. J. Neurosci. 15, 152-164.
30. Marinissen M. J. and Gutkind J. S. (2001) G-protein-coupled receptors and signaling networks: emerging paradigms. Trends Pharmacol. Sci. 22, 368-376.
31. 2-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor. J. Biol. Chem. 275, 9572-9580.
32. McCarthy K. D. and de Vellis J. (1980) Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue. J. Cell. Biol. 85, 890-902.
33. Miller R. H., Abney E. R., David S., Ffrench-Constant C., Lindsay R., Patel R., Stone J. and Raff M. C. (1986) Is reactive gliosis a property of a distinct subpopulation of astrocytes? J. Neurosci. 6, 22-29.
34. Renier G., Clement., Desfaits A. C. and Lambert A. (1996) Direct stimulatory effect of insulin-like growth factor-I on monocyte and macrophage tumor necrosis factor-alpha production Endocrinology 137, 4611-4618.
35. Selmaj K. W. and Raine C. S. (1988) Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro Ann. Neurol. 23, 339-346.
36. Sorg O. and Magistretti P. J. (1991) Characterization of the glycogenolysis elicited by vasoactive intestinal peptide, noradrenaline and adenosine in primary cultures of mouse cerebral cortical astrocytes. Brain Res. 563, 227-233.
37. Subbarao K. V. and Hertz L. (1990) Effect of adrenergic agonists on glycogenolysis in primary cultures of astrocytes. Brain Res. 536, 220-226.
38. Valverde A. M., Lorenzo M., Teruel T. and Benito M. (1995) cAMP inhibits IGF-I-induced mitogenesis in fetal rat brown adipocytes: role of p21 ras. Exp. Cell Res. 218, 305-309.
39. Valverde A. M., Teruel T., Lorenzo M. and Benito M. (1996) Involvement of Raf-1 kinase and protein kinase Cζ in insulin-like growth factor I-induced brown adipocyte mitogenic signaling cascades: inhibition by cyclic adenosine 3′,5′-monophosphate. Endocrinology 137, 3832-3841.
40. Wu J., Dent P., Jelinek T., Wolfman A., Weber M. J. and Sturgill T. W. (1993) Inhibition of the EGF-activated MAP kinase signaling pathway by adenosine 3′,5′-monophosphate. Science 262, 1065-1069.
41. 3H] dihydroalprenolol binding to β-adrenergic receptors in multiple sclerosis brain. Neurosci. Lett. 289, 75-77.