Deficiency of CIZ, a nucleocytoplasmic shuttling protein, prevents unloading-induced bone loss through the enhancement of osteoblastic bone formation in vivo

Bone

Volumn 40, Issue 4, 2007, Pages 852-860

  Hino, K ^a,b   Nakamoto, T ^c   Nifuji, A ^a   Morinobu, M ^a,b   Yamamoto, H ^b   Ezura, Y ^a   Noda, M ^a,d,e,f  

^a Tokyo Medical and Dental University ^*  (Japan)

^b EHIME UNIVERSITY   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d Excellence (COE) Program for the Frontier Research on Molecular Destruction and Reconstruction of To   (Japan)

^e JAPAN SOCIETY FOR THE PROMOTION OF SCIENCE   (Japan)

^f Hard Tissue Genome Research Center   (Japan)

Author keywords

CIZ; Mechanical stress; Osteoblast; Osteoporosis; Unloading

Indexed keywords

MATRIX PROTEIN; NUCLEOCYTOPLASMIC TRANSPORT PROTEIN; PROTEIN CIZ; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE MINERALIZATION; CELL ADHESION; CELL COMPARTMENTALIZATION; CELL NUCLEUS; CONTROLLED STUDY; FRACTURE; IN VIVO STUDY; MECHANICAL STRESS; MOUSE; NONHUMAN; OSSIFICATION; OSTEOBLAST; OSTEOLYSIS; OSTEOPOROSIS; PROMOTER REGION; PROTEIN DEFICIENCY; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; RISK FACTOR; SIGNAL TRANSDUCTION; WEIGHT BEARING; WILD TYPE;

ANIMALS; BONE MARROW CELLS; CELLS, CULTURED; HINDLIMB SUSPENSION; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NUCLEAR MATRIX-ASSOCIATED PROTEINS; NUCLEOCYTOPLASMIC TRANSPORT PROTEINS; OSTEOBLASTS; OSTEOGENESIS; OSTEOPOROSIS; TRANSCRIPTION FACTORS;

EID: 33847703731     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2006.03.019     Document Type: Article

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