Aneugenic potential of the nitrogen mustard analogues melphalan, chlorambucil and p-N,N-bis(2-chloroethyl)aminophenylacetic acid in cell cultures in vitro

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 617, Issue 1-2, 2007, Pages 125-137

  Efthimiou, M ^a   Andrianopoulos, C ^a   Stephanou, G ^a   Demopoulos, N A ^a   Nikolaropoulos, S S ^a  

^a UNIVERSITY OF PATRAS   (Greece)

Author keywords

Abnormal centrosome number; Chromosome malsegregation; Nitrogen mustard analogues

Indexed keywords

4 N,N BIS(2 CHLOROETHYL)AMINOPHENYLACETIC ACID; ALPHA TUBULIN; ANEUGEN; CHLORAMBUCIL; CHLORMETHINE; DNA; GAMMA TUBULIN; MELPHALAN; PHENYLACETIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ADULT; ANIMAL CELL; ARTICLE; CARCINOGENIC ACTIVITY; CARCINOGENICITY; CELL STRAIN; CENTROMERE; CENTROSOME; CHROMOSOME BREAKAGE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA PROBE; DOSE RESPONSE; DRUG MECHANISM; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE MUTATION; HUMAN; IMMUNOFLUORESCENCE; IN VITRO STUDY; LYMPHOCYTE CULTURE; MALE; MICRONUCLEUS; MICRONUCLEUS TEST; MOUSE; NONDISJUNCTION; NONHUMAN; PRIORITY JOURNAL; X CHROMOSOME;

ADULT; ANEUGENS; ANEUPLOIDY; ANIMALS; ANTINEOPLASTIC AGENTS, ALKYLATING; AZASTEROIDS; CELLS, CULTURED; CENTROMERE; CHLORAMBUCIL; CHROMOSOME ABERRATIONS; FEMALE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; LYMPHOCYTES; MALE; MELPHALAN; MICE; MICRONUCLEI, CHROMOSOME-DEFECTIVE; MICRONUCLEUS TESTS; NONDISJUNCTION, GENETIC; PHENYLACETATES;

BRASSICACEAE; EQUUS ASINUS;

EID: 33847702915     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2007.01.009     Document Type: Article

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