ANESTHESIA INDUCTION;
ANIMAL BEHAVIOR;
ANTINOCICEPTION;
ARTICLE;
CONTROLLED STUDY;
DRUG EFFECT;
DRUG MECHANISM;
DRUG TARGETING;
ELECTROENCEPHALOGRAM;
ELECTROENCEPHALOGRAPHY;
HYPNOSIS;
MOUSE;
NOCICEPTION;
NONHUMAN;
PRIORITY JOURNAL;
RAT;
SLEEP TIME;
STATISTICAL SIGNIFICANCE;
ANIMAL;
ANIMAL MODEL;
DRUG POTENTIATION;
HUMAN;
INSTITUTE FOR CANCER RESEARCH MOUSE;
INTRAVENOUS DRUG ADMINISTRATION;
MALE;
WISTAR RAT;
ORL1, a novel member of the opioid receptor family. Cloning, functional expression and localization
Mollereau C, Parmentier M, Mailleux P, et al. ORL1, a novel member of the opioid receptor family. Cloning, functional expression and localization. FEBS Lett 1994;341:33-8.
Molecular cloning and tissue distribution of a putative member of the rat opioid receptor gene family that is not a μ, δ, or κ receptor type
Bunzow JR, Saez C, Mortrud M, et al. Molecular cloning and tissue distribution of a putative member of the rat opioid receptor gene family that is not a μ, δ, or κ receptor type. FEBS Lett 1994;347:284-8.
Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor
Meunier JC, Mollereau C, Toll L, et al. Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor. Nature 1995;377:532-5.
Orphanin FQ: A neuropeptide that activates an opioidlike G protein-coupled receptor
Reinscheid RK, Nothacker HP, Bourson A, et al. Orphanin FQ: a neuropeptide that activates an opioidlike G protein-coupled receptor. Science 1995;270:792-4.
The molecular and behavioral pharmacology of the orphanin FQ/nociceptin peptide and receptor family
Mogil JS, Pasternak GW. The molecular and behavioral pharmacology of the orphanin FQ/nociceptin peptide and receptor family. Pharmacol Rev 2001;53:381-415.
Involvement of endogenous opioid systems in nociceptin-induced spinal antinociception in rats
Yu L-C, Lu J-T, Huang Y-H, et al. Involvement of endogenous opioid systems in nociceptin-induced spinal antinociception in rats. Brain Res 2002;945:88-96.
Lack of the nociceptin receptor does not affect acute or chronic nociceptin in mice
Bertorelli R, Bastia E, Citterio F, et al. Lack of the nociceptin receptor does not affect acute or chronic nociceptin in mice. Peptides 2002;23:1589-96.
Peptide and nonpeptide ligands for the nociceptin/ orphanin FQ receptor ORL1: Research tools and potential therapeutic agents
Zaveri N. Peptide and nonpeptide ligands for the nociceptin/ orphanin FQ receptor ORL1: research tools and potential therapeutic agents. Life Sci 2003;73:663-78.
Synthesis and SAR studies of 3-phenoxypropyl piperidine analogues as ORL1 (NOP) receptor agonists
Palin R, Barn DR, Clark JK, et al. Synthesis and SAR studies of 3-phenoxypropyl piperidine analogues as ORL1 (NOP) receptor agonists. Bioorg Med Chem Lett 2005;15:589-93.
An automated flinch detecting system for use in the formalin nociceptive bioassay
Yaksh TL, Ozaki G, McCumber D, et al. An automated flinch detecting system for use in the formalin nociceptive bioassay. J Appl Physiol 2001;90:2386-402.
The formalin test: A quantitative study of the analgesic effects of morphine, meperidine and brainstem stimulation in rats and cats
Dubuisson D, Dennis SG. The formalin test: a quantitative study of the analgesic effects of morphine, meperidine and brainstem stimulation in rats and cats. Pain 1977;4:161-74.
Cesura A, Adam G. 8-substituted-1,3,8-triazaspiro[4.5]decan-4-on derivatives. Eur. Pat. 0856514. August 5, 1998
Cesura A, Adam G. 8-substituted-1,3,8-triazaspiro[4.5]decan-4-on derivatives. Eur. Pat. 0856514. August 5, 1998.
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The effects of anesthetics on action potentials in the cerebral cortex of the cat
Derbyshire AJ, Rempel B, Forbes A, Lambert EF. The effects of anesthetics on action potentials in the cerebral cortex of the cat. Am J Physiology 1936;116:577-96.
Neurophysiologic effects of general anesthetics (1973). I. The electroencephalogram and sensory evoked responses in man
Clark DL, Rosner BS. Neurophysiologic effects of general anesthetics (1973). I. The electroencephalogram and sensory evoked responses in man. Anesthesiology 1973;38:564-82.
I653 and isoflurane produce similar dose-related changes in the electroencephalogram of pigs
Rampil IJ, Weiskopf RB, Brown JG, et al. I653 and isoflurane produce similar dose-related changes in the electroencephalogram of pigs. Anesthesiology 1988;69:298-302.
The EEG burst suppression threshold test for the determination of CNS sensitivity to intravenous anesthetics in rats
Korkmaz S, Wahlstrom G. The EEG burst suppression threshold test for the determination of CNS sensitivity to intravenous anesthetics in rats. Brain Res Brain Res Protoc 1997;1: 378-84.