Lack of endothelial nitric oxide synthase-derived nitric oxide formation favors hypertrophy in adult ventricular cardiomyocytes

Hypertension

Volumn 49, Issue 1, 2007, Pages 193-200

  Wenzel, Sibylle ^a   Rohde, Cornelia ^a   Wingerning, Sandra ^a   Roth, Joachim ^a   Kojda, Georg ^b   Schlüter, Klaus Dieter ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Cytokine; Myocardial hypertrophy; TGF ; TNF

Indexed keywords

CYTOKINE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; MITOGEN ACTIVATED PROTEIN KINASE P38; N(G) NITROARGININE; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; 4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4-(4-FLUOROPHENYL)-2-(4-HYDROXYPHENYL)-5-(4-PYRIDYL)IMIDAZOLE; ENZYME INHIBITOR; IMIDAZOLE DERIVATIVE; PROTEIN; PYRIDINE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL CULTURE; CELL GROWTH; CELL SIZE; CELL TYPE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HEART FAILURE; HEART MUSCLE CELL; HEART VENTRICLE; HEART VENTRICLE HYPERTROPHY; HYPERTROPHY; KNOCKOUT GENE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; RAT; ANIMAL; BIOSYNTHESIS; DRUG ANTAGONISM; DRUG EFFECT; MALE; METABOLISM; MOUSE; MOUSE MUTANT; PATHOLOGY; WISTAR RAT;

ANIMALS; CELLS, CULTURED; CYTOKINES; ENZYME ACTIVATION; ENZYME INHIBITORS; HEART VENTRICLES; HYPERTROPHY; IMIDAZOLES; MALE; MICE; MICE, KNOCKOUT; MYOCYTES, CARDIAC; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; NITROARGININE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEINS; PYRIDINES; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES;

EID: 33847622007     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.0000250468.02084.ce     Document Type: Article

References (40)

1. Huang PL, Huang ZH, Mashimo H, Bloch KD, Moskowitz MA, Bevan JA, Fishman MC. Hypertension in mice lacking the gene for endothelial nitric oxide synthase. Nature. 1995;377:239-242.
2. Feron O, Dessy C, Opel DJ, Arstall MA, Kelly RA, Michel T. Modulation of the endothelial nitric-oxide synthase-caveolin interaction in cardiac myocytes: implication for the autonomic regulation of the heart rate. J Biol Chem. 1998;273:30249-30254.
3. Yamamoto S, Tsutsui H, Tagawa H, Sato K, Takahashi M, Tada H, Yamamotot M, Katoh M, Egashira K, Takeshita A. Role of myocardial nitric oxide in β-adrenergic hyporesponsiveness in heart failure. Circulation. 1997;95:1111-1114.
4. Sears CA, Bryant SM, Ashley EA, Lygate CA, Rakovic S, Wallis HL, Neubauer S, Terrar DA, Casadei B. Cardiac neuronal nitric oxide synthase isoform regulates myocardial contraction and calcium handling. Circ Res. 2003;92:e52-e59.
5. Bayraktutan U, Yang Z-K, Shah AM. Selective dysregulation of nitric oxide synthase type 3 in cardiac myocytes but not coronary microvascular endothelial cells of spontaneously hypertensive rats. Cardiovasc Res. 1998;38:719-726.
6. Piech A, Massart PE, Dessy C, Feron O, Havaux X, Morel N, Venoverschelde J-L, Donckier J, Balligand J-L. Decreased expression of myocardial eNOS and caveolin in dogs with hypertrophic cardiomyopathy. Am J Physiol Heart Circ Physiol. 2002;282:H219-H231.
7. Massion PB, Feron O, Dessy C, Balligand J-L. Nitric oxide and cardiac function: ten years after, and continuing. Circ Res. 2003;93:388-398.
8. 2+ blockers prevent myocardial remodeling induced by chronic NO inhibition in rats. Hypertension. 2003;41:963-967.
9. 1 expression in adult ventricular cardiomyocytes. FASEB J. 2001;15:2291-2293.
10. Wenzel S, Müller C, Piper HM, Schlüter K-D. p38 MAP kinase in cultured adult ventricular cardiomyocytes: expression and involvement in hypertrophic signalling. Eur Heart J. 2005;7:453-460.
11. Schlüter K-D, Schreiber D. Adult ventricular cardiomyocytes. Isolation and culture. Meth Mol Biol. 2005;290:305-314.
12. Schlüter K-D, Piper HM. Isolation and culture of adult ventricular cardiomyocytes. In: Dhein S, Mohr FW, Delmar M, eds. Practical Methods in Cardiovasc Research. Berlin-Heidelberg, Germany: Springer Verlag; 2005:557-567.
13. Pinson A, Schlüter K-D, Zhou XJ, Schwartz P, Kessler-Icekson G, Piper HM. Alpha and beta adrenergic stimulation of protein synthesis in cultured adult ventricular cardiomyocytes. J Mol Cell Cardiol. 1993;25:477-490.
14. Schäfer M, Pönicke K, Heinroth-Hoffmann I, Brodde O-E, Piper HM, Schlüter K-D. β-Adrenoceptor stimulation attenuates the hypertrophic effect of α-adrenoceptor stimulation in adult ventricular rat cardiomyocytes. J Am Coll Cardiol. 2001;37:300-307.
15. Taimor G, Schlüter K-D, Piper HM. Hypertrophy-associated gene induction after β-adrenergic stimulation in adult cardiomyocytes. J Mol Cell Cardiol. 2001;33:503-511.
16. Gearing AJH, Cartwright JE, Wadhwa M. Biological and immunological assays for cytokines. In: Thompson AW, ed. The Cytokine Handbook. London, United Kingdom: Academic Press Ltd; 1994:507-524.
17. Schlüter K-D, Simm A, Schäfer M, Taimor G, Piper HM. Early response kinase and PI 3-kinase activation in adult cardiomyocytes and their role in hypertrophy. Am J Physiol Heart Circ Physiol. 1999;276:H1655-H1663.
18. Weiss HR, Haim T, Zhang Q, Vaks Y. Ethanol reduces cardiac myocyte function through activation of the nitric oxide-cyclic GMP pathway. Pharmacology. 2003;67:59-66.
19. Weiss HR, Gandhi A, Scholz PM. Negative effect of nitric oxide shortening-frequency relationship in cardiac myocytes is diminished after simulated ischemia-reperfusion. Basic Res Cardiol. 2003;98:311-318.
20. Strijdom H, Muller C, Lochner A. Direct intracellular nitric oxide detection in isolated adult cardiomyocytes: flow cytometric analysis using fluorescence probe, diaminofluorescein. J Mol Cell Cardiol. 2004;37:897-902.
21. 2+-calcineurin-NFAT cascade in cardiac myocytes. Cardiovasc Res. 2004;63:450-457.
22. 1-adrenoceptor signaling in adult rat cardiac myocytes. Am J Physiol Cell Physiol. 2002;282:C926-C934.
23. Lambert IH. Reactive oxygen species regulate swelling-induced taurine efflux in NIH3T3 mouse fibroblasts. J Membr Biol. 2003;192:19-32.
24. Silveira LR, Pereira da Silva L, Juel C, Hellsten Y. Formation of hydrogen peroxide and nitric oxide in rat skeletal muscle cells during contractions. Free Radic Biol Med. 2003;35:455-464.
25. 1A-adrencoeptors. Naunyn-Schmiedeberg's Arch Pharmacol. 2001;364:444-453.
26. Bubikat A, de Windt LJ, Zetsche B, Fabritz L, Sickler H, Eckhardt D, Gödecke A, Baba HA, Kuhn M. Local ANP signaling prevents hypertensive cardiac hypertrophy in endothelial NO synthase (eNOS)-deficient mice. J Biol Chem. 2005;280:21594-25599.
27. Bouwman RA, Musters RJ, van Beek-Harmsen BJ, de Lange JJ, Boer C. Reactive oxygen species precede protein kinase C-δ- activation independent of adenosine triphosphate-sensitive mitochondrial channel opening in sveofluaran-induced cardioprotection. Anesthesiology. 2004;100:506-514.
28. Novalija E, Kevin LG, Camara AK, Bosnjak ZJ, Kampine JP, Stowe DF. Reactive oxygen species precede the epsilon isoform of protein kinase C in anesthetic preconditioning signaling cascade. Anesthesiology. 2003;99:421-428.
29. 2+-dependent PKC isoforms unmasks ERK-dependent hypertrophic growth evoked by phenylephrine in adult ventricular cardiomyocytes. Cardiovasc Res. 2004;63:553-560.
30. Olzinski AR, McCafferty TA, Zhao SQ, Behm DJ, Eybye ME, Maniscalco K, Bentley R, Frazier KS, Milliner CM, Mirabile RC, Coatney RW, Willette RN. Hypertension target organ damage is attenuated by p38 MAP kinase inhibitor: Role of systemic blood pressure and endothelial protection. Cardiovasc Res. 2005;66:170-178.
31. Kobayashi N, Yoshida K, Mita S, Honda T, Nakano S, Tsuboku Y, Matsuoka H. Betaxolol stimulates eNOS production associated with LOX-1 and VEGF in Dahl sensitive rats. J Hypertens. 2004;22:1397-1402.
32. Rossi MA, Ramos SG, Prado CM. Chronic inhibition of nitric oxide synthase induces hypertension and cardiomyocytes mitochondrial and myocardial collagen remodelling in the absence of hypertrophy. J Hypertens. 2003;21:993-1001.
33. Ichinose F, Bloch KD, Wu JC, Hataishi R, Aretz HT, Picrad HM, Scherrer-Crosbie M. Pressure overload-induced left ventricular hypertrophy and dysfunction in mice are exacerbated by congenital NOS3 deficiency. Am J Physiol Heart Circ Physiol. 2004;286:H1070-H1075.
34. Inserte J, Perelli A, Agullo L, Ruiz-Meana M, Schlüter K-D, Escalona N, Graupera M, Bosch J, Garcia-Dorado D. Left ventricular hypertrophy in rats with biliary cirrhosis. Hepatology. 2003;38:589-598.
35. Pedram KJK, Razandi M, Levin ER. Estrogen prevents cardiomyocyte apoptosis through inhibition of reactive oxygen species and differential regulation of p38 MAP kinase isoforms. J Biol Chem. 2006;281:6760-6767.
36. Li Z, Tran TT, Ma JY, O'Young G, Kapoun AM, Chakravarty S, Dugar S, Schreiner G, Protter AA. p38 Alpha mitogen-activated protein kinase inhibition improves cardiac function and reduces myocardial damage in isoproterenol-induced acute myocardial injury in rats. J Cardiovasc Pharmacol. 2004;44:486-492.
37. Zoccali C, Mallamaci F, Maas R, Benedetto FA, Tripepi G, Malatino LS, Cataliotti A, Ballanuova I, Böger R. Left ventricular hypertrophy, cardiac remodeling and asymmetric dimethylarginine (ADMA) in hemodialysis patients. Kidney Int. 2002;62:339-345.
38. Ratajczak P, Damy T, Heymes C, Oliveiro P, Marotte F, Robidel E, Sercombe R, Boczkowski J, Rappaport L, Samuel J-L. Caveolin-1 and -3 dissociation from caveolae to cytosol in the heart during aging and after myocardial infarction in rat. Cardiovasc Res. 2003;57:358-369.
39. Smith CJ, Sun D, Hoegler C, Roth BS, Zhang X, Zhao G, Xu X-B, Kobari Y, Pritchard K Jr, Sessa WC, Hintze TH. Reduced expression of vascular endothelial NO synthase and cyclooxygenase-1 in heart failure. Circ Res. 1996;78:58-64.
40. Gomes Pessanha M, Mandarim de Lacerda CA, Hahn MD. Stereology and immunohistochemistry of the myocardium in experimental hypertension: long-term and low-dosage administration of inhibitor of the nitric oxide synthesis. Pathobiology. 1999;67:26-33.