Decreased expression of myocardial eNOS and caveolin in dogs with hypertrophic cardiomyopathy

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 282, Issue 1 51-1, 2002, Pages

  Piech, A ^a   Massart, P E ^a   Dessy, C ^a   Feron, O ^a   Havaux, X ^a   Morel, N ^a   Vanoverschelde, J L ^a   Donckier, J ^a   Balligand, J L ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

Cardiac hypertrophy; Diastolic function; Endothelial nitric oxide synthase; Perinephritic hypertension

Indexed keywords

CAVEOLIN 1; CAVEOLIN 3; CITRULLINE; HEAT SHOCK PROTEIN 90; N(G) NITROARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA PRESSURE; ARTICLE; BLOOD VESSEL TONE; CONTROLLED STUDY; CORONARY BLOOD VESSEL; DOG; ECHOCARDIOGRAPHY; ENZYME ACTIVITY; HEART LEFT VENTRICLE FUNCTION; HEMODYNAMICS; HYPERTROPHIC CARDIOMYOPATHY; IMMUNOHISTOCHEMISTRY; MESENTERY BLOOD VESSEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RENOVASCULAR HYPERTENSION; VASCULAR ENDOTHELIUM; WESTERN BLOTTING;

EID: 0036082638     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.2002.282.1.h219     Document Type: Article

References (47)

1. Alterations of myocardial blood flow associated with experimental canine left ventricular hypertrophy secondary to valvular aortic stenosis
2. Regulation of cardiac beta-adrenergic response by nitric oxide
3. Nitric oxide synthases and cardiac muscle. Autocrine and paracrine influences
4. Nitric oxide-dependent parasympathetic signaling is due to activation of constitutive endothelial (type III) nitric oxide synthase in cardiac myocytes
5. Molecular regulation of NO synthase in the heart
6. Dobutamine enhances cardiodepressant effects of receptor-mediated coronary endothelial stimulation
7. Selective dysregulation of nitric oxide synthase type 3 in cardiac myocytes but not coronary microvascular endothelial cells of spontaneously hypertensive rat
8. Regulation by cAMP of post-translational processing and subcellular targeting of endothelial nitric-oxide synthase (type 3) in cardiac myocytes
9. Evidence for involvement of the PKC-α isoform in myogenic tone of the coronary microcirculation
10. Low-dose endothelin-1 potentiates volume-induced secretion of atrial natriuretic factor
11. Hypertrophy, fibrosis and diastolic dysfunction in early canine experimental hypertension
12. Hydroxy-methylglutaryl-coenzyme A reductase inhibition promotes endothelial nitric oxide synthase activation through a decrease in caveolin abundance
13. Hypercholesterolemia decreases nitric oxide production by promoting the interaction of caveolin and endothelial nitric oxide synthase
14. Modulation of the endothelial nitric-oxide synthase-caveolin interaction in cardiac myocytes. Implications for the autonomic regulation of heart rate
15. The endothelial nitric-oxide synthase-caveolin regulatory cycle
16. Time constant of isovolumic pressure fall: Determinants in the working left ventricle
17. Dynamic activation of endothelial nitric oxide synthase by Hsp 90
18. Targeting of nitric oxide synthase to endothelial cell caveolae via palmitoylation: Implications for nitric oxide signaling
19. Sympathetic augmentation of cardiac function in developing hypertension in conscious dogs
20. Studies on the first derivative of the ventricular pressure pulse in man
21. Reconstitution of an endothelial nitric-oxide synthase (eNOS), hsp90, and caveolin-1 complex in vitro. Evidence that hsp90 facilitates calmodulin stimulated displacement of eNOS from caveolin-1
22. Modulation of left ventricular relaxation in isolated ejecting heart by endogenous nitric oxide
23. Modulation of mouse cardiac function in vivo by eNOS and ANP
24. Contribution of caveolin protein abundance to augmented nitric oxide signaling in conscious dogs with pacing-induced heart failure
25. Cellular and molecular mechanisms of endothelial cell dysfunction
26. Effects of increasing afterload on early diastolic dysfunction in hypertrophic nonobstructive cardiomyopathy
27. Diastolic properties in canine hypertensive left ventricular hypertrophy: Effects of angiotensin converting enzyme inhibition and angiotensin II type-1 receptor blockade
28. Load-sensitive diastolic relaxation in hypertrophied left ventricles
29. Hypertension in mice lacking the gene for endothelial nitric oxide synthase
30. Effects of the nitric oxide donor sodium nitroprusside on intracellular pH and contraction in hypertrophied myocytes
31. Inhibition of nitric oxide synthase augments myocardial contractile responses to β-adrenergic stimulation
32. Nitric oxide and cardiac function
33. Endothelial nitric oxide synthase increases in left atria of dogs with pacing-induced heart failure
34. Impaired endothelium-dependent regulation of ventricular relaxation in pressure-overload cardiac hypertrophy
35. 2+-calmodulin and caveolin
36. Endothelium-derived hyperpolarizing factor(s): Updating the unknown
37. Contractile properties of small arterial resistance vessels in spontaneously hypertensive and normotensive rats
38. Downregulation of caveolin by chronic β-adrenergic receptor stimulation in mice
39. The production of persistant arterial hypertension by cellophane perinephritis
40. NO and cardiac diastolic function
41. In situ flow activates endothelial nitric oxide synthase in luminal caveolae of endothelium with rapid caveolin dissociation and calmodulin association
42. Impaired early left ventricular relaxation in coronary artery disease: Effects of intracoronary nifedipine
43. CROPA a research-oriented program for automatic processing of cardiovascular signals
44. Alterations of the architecture of subendocardial arterioles in patients with hypertrophic cardiomyopathy and impaired coronary vasodilator reserve: A possible cause for myocardial ischemia
45. Role of nitric oxide in the regulation of oxygen consumption in conscious dogs
46. Anatomic distribution of nitric oxide synthase in the heart
47. Hemodynamic determinants of the time course of fall in canine left ventricular pressure