Evaluation of CSF-Chlamydia pneumoniae, CSF-tau, and CSF-Abeta42 in Alzheimer's disease and vascular dementia

Journal of Neurology

Volumn 254, Issue 2, 2007, Pages 154-159

  Paradowski, Bogusław ^a   Jaremko, Malgorzata ^a   Dobosz, Tadeusz ^a   Leszek, Jerzy ^a   Noga, Leszek ^a  

^a WROCLAW MEDICAL UNIVERSITY   (Poland)

Author keywords

A 42; Alzheimer's disease; Cerebrospinal fluid; Chlamydia pneumoniae; Tau; Vascular dementia

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; BACTERIAL DNA; TAU PROTEIN;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; BACTERIUM DETECTION; CEREBROSPINAL FLUID ANALYSIS; CHLAMYDOPHILA PNEUMONIAE; COMPARATIVE STUDY; CONTROLLED STUDY; DNA DETERMINATION; FEMALE; HUMAN; HYPOTHESIS; MAJOR CLINICAL STUDY; MALE; MULTIINFARCT DEMENTIA; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DETERMINATION;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; CHI-SQUARE DISTRIBUTION; CHLAMYDOPHILA PNEUMONIAE; DEMENTIA, VASCULAR; FEMALE; HUMANS; MALE; ODDS RATIO; PEPTIDE FRAGMENTS; TAU PROTEINS;

EID: 33847620859     PISSN: 03405354     EISSN: 14321459     Source Type: Journal    
DOI: 10.1007/s00415-006-0298-5     Document Type: Article

References (35)

1. Andreasen N, Hesse C, Davidsson P, et al. (1999) Cerebrospinal fluid b-Amyloid 1-42 in Alzheimer Disease: differences between early-and late-onset Alzheimer disease and stability during the course of disease. Arch Neurol 56:673-680
2. Andreasen N, Minnthon L, Davidsson P, et al. (2001) Evaluation CSF-tau and CSF-Abeta42 as diagnostic markers for Alzheimer disease in clinical practice. Arch Neurol 58:373-379
3. Balin BJ, Gerard H.C, Arking EJ, et al. (1998) Identification and localization of Chlamydia pneumoniae in the Alzheimer's brain. Med Microbiol Immunol 187:23-42
4. Bauer J, Ganter U, Strauss SS, et al. (1992) The participation of interleukin-6 in the pathogenesis of Alzheimer's disease. Res Immunol 143:650-657
5. Blasi F, Centanni S, Allegra L. (2004) Chlamydia pneumoniae: crossing the barriers? Eur Respir J 23:499-500
6. Dechend R, Maass M, Gieffer J, et al. (1999) Chlamydia pneumoniae infection of vascular smooth muscle and endothelial cells activates NF-kappaB and induces tissue factor and PAI-1 expression: a potential link to accelerated arteriosclerosis. Circulation 100:1369-1373
7. Galasko D, Clark C, Motter R, et al. (1998) High cerebrospinal fluid tau and low amyloid β42 levels in the clinical diagnosis of Alzheimer disease and relation to apolipoprotein E genotype. Arch Neurol. 55:937-945
8. Gaydos CA, Quinn TC, Eiden JJ. (1992) Identification of Chlamydia pneumoniae by DNA amplification of the 16S rRNA gene. J Clin Microbiol 30:796-800
9. Gieffers J, Pohl D, Treib J, et al. (2001) Presence of Chlamydia pneumoniae DNA in the cerebral spinal fluid is a common phenomenon in a variety of neurological diseases and not restricted to multiple sclerosis. Ann Neurol 49:585-589
10. Gieffers J, Reusche E, Solbach W, et al. (2000) Failure to detect Chlamydia pneumoniae in brain sections of Alzheimer's disease patients. J Clin Microbiol 38:881-882
11. Gieffers J, van Zandbergen G, Rupp J, et al. (2004) Phagocytes transmit Chlamydia pneumoniae from the lung to the vasculature. Eur Respir J 23:506-510
12. Grimaldi LM, Pincherle A, Martinelli-Boneschi F, et al. (2003) An MRI study of Chlamydia pneumoniae in Italian multiple sclerosis patients. Mult Scler 9:467-471
13. Itzhaki RF, Dobson CB, Lin WR, et al. (2001) Association of HSV-1 and apolipoprotein E-verepsilon4 in Alzheimer's disease. J Neurovirol 6:570-571
14. Itzhaki RF, Lin WR, Shang D, et al. (1997) Herpes simplex virus type 1 in brain and risk of Alzheimer's disease. Lancet 349:241-244
15. Itzhaki RF, Wozniak MA, Appelt DM, et al. (2004) Infiltration of the brain by pathogens causes Alzheimer's disease. Neurobiol Aging 25:619-627
16. Jamieson GA, Maitland NJ, Wilcock GK, et al.( 1991) Latent herpes simplex virus type 1 in normal and Alzheimer's disease brains. J Med Virol 33:224-227
17. Kapaki E, Paraskevas GP, Zalonis I, et al. (2003) CSF tau protein and β-amyloid (1-42) in Alzheimer's disease diagnosis: discrimination from normal ageing and other dementias in the Greek population. Eur J Neurol 10:119-128
18. Lin WR, Wozniak MA, Wilcock GK, et al. (2002) Cytomegalovirus is present in a very high proportion of brains from vascular dementia patients. Neurobiol Dis 9:82-87
19. Little CS, Hammond CJ, MacIntyre A, et al. (2004) Chlamydia pneumoniae induces Alzheimer-like amyloid plaque brains of BALB/c mice. Neurobiol Aging 25:419-429
20. Loeb MB, Molloy DW, Smieja M, et al. (2004) A Randomized, Controlled Trial of Doxycycline and Rifampin for Patients with Alzheimer's Disease. J Am Geriatr Soc 52:381-387
21. MacIntyre A, Abramov R, Hammond CJ, et al. (2003) Chlamydia pneumoniae infection promotes the transmigration of monocytes through human brain endothelial cells. J Neurosci Res 71:740-750
22. Maddalena A, Papassotiropoulos A, Muller-Tillmanns B, et al. (2003) Biochemical diagnosis of Alzheimer disease by measuring the cerebrospinal fluid ratio of phosphorylated tau protein to b-amyloid peptide 42. Arch Neurol 60:1202-1206
23. Maass M, Bartels C, Engel P, et al. (1998) Endovascular presence of viable Chlamydia pneumoniae is a common phenomenon in coronary artery disease. J Am Coll Cardiol 31:827-832
24. Neumann FJ (2002) Chlamydia pneumoniae-atherosclerosis link: a sound concept in search for clinical relevance. Circulation 106:2414-2416
25. O'Brien MD (1988) Vascular dementia is underdiagnosed. Arch Neurol 45:797-798
26. Ring RH, Lyons JM. (2000) Failure to detect Chlamydia pneumoniae in the late-onset Alzheimer's brain. J Clin Microbiol 38:2591-2594
27. Sadowski M, Pankiewicz J, Scholtzova H, et al. (2004) Links Between the Pathology of Alzheimer's Disease and Vascular Dementia. Neurochemical Research 29:257-1266
28. Sjögren M, Vanderstichele H, Agren H, et al. (2001) Tau and Aβ in cerebrospinal fluid from healthy adults 21-93 years of age: establishment of reference values. Clin Chem 47:1776-1781
29. Sunderland T, Linker G, Mirza N, et al. (2003) Decreased beta-amyloid1-42 and increased tau levels in cerebrospinal fluid of patients with Alzheimer disease. JAMA 289:2094-2103
30. Taylor GS, Vipond IB, Paul LD, et al. (2002) Failure to correlate C. pneumoniae with late onset Alzheimer's disease. Neurology 59:142-143
31. Walsh PS, Metzger DA, Higuchi R. (1991) Chelex 100 as a medium for simple extraction of DNA for PCR-based typing from forensic material. Biotechniques 10:506-513
32. Ward ME (1999) Mechanisms of chlamydia-induced disease. In: Stephens RS, eds. Chlamydia: Intracellular Biology, Pathogenesis, and Immunity, Washington D.C., ASM press, pp. 171-210
33. Wisniewski HM, Wegiel J. (1995) The neuropathology of Alzheimer's disease. Neuroimaging Clin N Am 5:45-57
34. Wozniak MA, Cookson A, Wilcock GK, et al. (2003) Absence of Chlamydia pneumoniae in brain of vascular dementia patients. Neurobiol Aging 24:761-765
35. Yamamoto H, Watanabe T, Miyazaki A, et al. (2005) High prevalence of Chlamydia pneumoniae antibodies and increased high-sensitive C-reactive protein in patients with vascular dementia. J Am Geriatr Soc 53:583-589