Development of hydrocephalus in mice expressing the Gi-coupled GPCR Ro1 RASSL receptor in astrocytes

Journal of Neuroscience

Volumn 27, Issue 9, 2007, Pages 2309-2317

  Sweger, Elizabeth J ^a   Casper, Kristen B ^a   Scearce Levie, Kimberly ^b   Conklin, Bruce R ^b   McCarthy, Ken D ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Astrocyte; Gi; Hydrocephalus; Opioid; RASSL; SCO; Tetracycline

Indexed keywords

BETA GALACTOSIDASE; DOXYCYCLINE; G PROTEIN COUPLED RECEPTOR; GLIAL FIBRILLARY ACIDIC PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; RO1 RASSL RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN VENTRICLE; BREEDING; CELL COMMUNICATION; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFECT; EPENDYMA CELL; FEMALE; HYDROCEPHALUS; MALE; MORPHOLOGY; MOUSE; NONHUMAN; PATHOGENESIS; PERINATAL PERIOD; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; TRANSGENIC MOUSE; WEANING;

ANIMALS; ASTROCYTES; BRAIN; DISEASE MODELS, ANIMAL; DOXYCYCLINE; GLIAL FIBRILLARY ACIDIC PROTEIN; HYDROCEPHALUS; IMMUNOHISTOCHEMISTRY; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; NEUROGLIA; RECEPTORS, OPIOID, KAPPA; UP-REGULATION;

EID: 33847421779     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4565-06.2007     Document Type: Article

References (68)

1. Araque A, Li N, Doyle RT, Haydon PG (2000) SNARE protein-dependent glutamate release from astrocytes. J Neurosci 20:666-673.
2. Araque A, Carmignoto G, Haydon PG (2001) Dynamic signaling between astrocytes and neurons. Annu Rev Physiol 63:795-813.
3. 2+- elevations in astrocytes in hippocampal slices. J Neurosci 22:2443-2450.
4. Bach A, Lallemand Y, Nicola MA, Ramos C, Mathis L, Maufras M, Robert B (2003) Msx1 is required for dorsal diencephalon patterning. Development 130:4025-4036.
5. Blackshear PJ, Graves JP, Stumpo DJ, Cobos I, Rubenstein JL, Zeldin DC (2003) Graded phenotypic response to partial and complete deficiency of a brain-specific transcript variant of the winged helix transcription factor RFX4. Development 130:4539-4552.
6. Blount JP, Campbell JA, Haines SJ (1993) Complications in ventricular cerebrospinal fluid shunting. Neurosurg Clin N Am 4:633-656.
7. Bondurant CP, Jimenez DF (1995) Epidemiology of cerebrospinal fluid shunting. Pediatr Neurosurg 23:254-258; discussion 259.
8. Carmignoto G, Pizzorusso T, Tia S, Vicini S (1997) Brain-derived neurotrophic factor and nerve growth factor potentiate excitatory synaptic transmission in the rat visual cortex. J Physiol (Lond) 498:153-164.
9. Casey AT, Kimmings EJ, Kleinlugtebeld AD, Taylor WA, Harkness WF, Hayward RD (1997) The long-term outlook for hydrocephalus in childhood. A ten-year cohort study of 155 patients. Pediatr Neurosurg 27:63-70.
10. Chung JH, Whiteley M, Felsenfield G (1993) A 5′ element of the chicken beta-globin domain serves as an insulator in human erythroid cells and protects against position effect in Drosophila. Cell 74:505-514.
11. Costa T, Cotecchia S (2005) Historical review: negative efficacy and the constitutive activity of G-protein-coupled receptors. Trends Pharmacol Sci 26:618-624.
12. Coward P, Wada HG, Falk MS, Chan SD, Meng F, Akil H, Conklin BR (1998) Controlling signaling with a specifically designed Gi-coupled receptor. Proc Natl Acad Sci USA 95:352-357.
13. + in rat hippocampus. J Neurophysiol 87:87-102.
14. Del Bigio MR (2004) Cellular damage and prevention in childhood hydrocephalus. Brain Pathol 14:317-324.
15. Ding Y, Lai Q, McAllister IJ, Canady AI (2001) Impaired motor learning in children with hydrocephalus. Pediatr Neurosurg 34:182-189.
16. Dominguez-Pinos MD, Paez P, Jimenez AJ, Weil B, Arraez MA, Perez-Figares JM, Rodriguez EM (2005) Ependymal denudation and alterations of the subventricular zone occur in human fetuses with a moderate communicating hydrocephalus. J Neuropathol Exp Neurol 64:595-604.
17. Eckstein HB, Macnab GH (1966) Myelomeningocele and hydrocephalus. The impact of modern treatment. Lancet 1:842-845.
18. Estivill-Torrus G, Vitalis T, Fernandez-Llebrez P, Price DJ (2001) The transcription factor Pax6 is required for development of the diencephalic dorsal midline secretory radial glia that form the subcommissural organ. Mech Dev 109:215-224.
19. Fernandez-Llebrez P, Grondona JM, Perez J, Lopez-Aranda MF, Estivill-Torrus G, Llebrez-Zayas PF, Soriano E, Ramos C, Lallemand Y, Bach A, Robert B (2004) Msx1-deficient mice fail to form prosomere 1 derivatives, subcommissural organ, and posterior commissure and develop hydrocephalus. J Neuropathol Exp Neurol 63:574-586.
20. Fernell E, Hagberg G, Hagberg B (1990) Infantile hydrocephalus - the impact of enhanced preterm survival. Acta Paediatr Scand 79:1080-1086.
21. Fernell E, Hagberg G, Hagberg B (1994) Infantile hydrocephalus epidemiology: an indicator of enhanced survival. Arch Dis Child Fetal Neonatal Ed 70:F123-F128.
22. Fiacco TA, McCarthy KD (2004) Intracellular astrocyte calcium waves in situ increase the frequency of spontaneous AMPA receptor currents in CA1 pyramidal neurons. J Neurosci 24:722-732.
23. Fletcher JM, Francis DJ, Thompson NM, Davidson KC, Miner ME (1992) Verbal and nonverbal skill discrepancies in hydrocephalic children. J Clin Exp Neuropsychol 14:593-609.
24. Fletcher JMDM, Northrup H (2000) Hydrocephalus. In: Pediatric neuropsychology research, theory, and practice (Yeates KO, Ris MD, Taylor HG, eds), pp 25-46. New York: Guilford.
25. Fukumizu M, Takashima S, Becker LE (1996) Glial reaction in periventricular areas of the brainstem in fetal and neonatal posthemorrhagic hydrocephalus and congenital hydrocephalus. Brain Dev 18:40-45.
26. +]o and field potentials in dentate gyrus and area CA1 of human epileptic hippocampus. Neurosci Lett 249:91-94.
27. Hough LB, Nalwalk JW, Chen Y, Schuller A, Zhu Y, Zhang J, Menge WM, Leurs R, Timmerman H, Pintar JE (2000) Improgan, a cimetidine analog, induces morphine-like antinociception in opioid receptor-knockout mice. Brain Res 880:102-108.
28. Itoh K, Cheng L, Kamei Y, Fushiki S, Kamiguchi H, Gutwein P, Stoeck A, Arnold B, Altevogt P, Lemmon V (2004) Brain development in mice lacking L1-L1 homophilic adhesion. J Cell Biol 165:145-154.
29. Jimenez AJ, Tome M, Paez P, Wagner C, Rodriguez S, Fernandez-Llebrez P, Rodriguez EM, Perez-Figares JM (2001) A programmed ependymal denudation precedes congenital hydrocephalus in the hyh mutant mouse. J Neuropathol Exp Neurol 60:1105-1119.
30. Jones HC, Bucknall RM (1988) Inherited prenatal hydrocephalus in the H-Tx rat: a morphological study. Neuropathol Appl Neurobiol 14:263-274.
31. Jones HC, Dack S, Ellis C (1987) Morphological aspects of the development of hydrocephalus in a mouse mutant (SUMS/NP). Acta Neuropathol (Berl) 72:268-276.
32. Jones HC, Lopman BA, Jones TW, Carter BJ, Depelteau JS, Morel L (2000) The expression of inherited hydrocephalus in H-Tx rats. Childs Nerv Syst 16:578-584.
33. Jones HC, Carter BJ, Depelteau JS, Roman M, Morel L (2001a) Chromosomal linkage associated with disease severity in the hydrocephalic H-Tx rat. Behav Genet 31:101-111.
34. Jones HC, Depelteau JS, Carter BJ, Lopman BA, Morel L (2001b) Genome-wide linkage analysis of inherited hydrocephalus in the H-Tx rat. Mamm Genome 12:22-26.
35. Jones HC, Yehia B, Chen GF, Carter BJ (2004) Genetic analysis of inherited hydrocephalus in a rat model. Exp Neurol 190:79-90.
36. Kondziella D, Qu H, Ludemann W, Brinker T, Sletvold O, Sonnewald U (2003) Astrocyte metabolism is disturbed in the early development of experimental hydrocephalus. J Neurochem 85:274-281.
37. Krebs DL, Metcalf D, Merson TD, Voss AK, Thomas T, Zhang JG, Rakar S, O'Bryan MK, Willson TA, Viney EM, Mielke LA, Nicola NA, Hilton DJ, Alexander WS (2004) Development of hydrocephalus in mice lacking SOCS7. Proc Natl Acad Sci USA 101:15446-15451.
38. Laurence KM, Coates S (1962) The natural history of hydrocephalus. Detailed analysis of 182 unoperated cases. Arch Dis Child 37:345-362.
39. Louvi A, Wassef M (2000) Ectopic engrailed 1 expression in the dorsal midline causes cell death, abnormal differentiation of circumventricular organs and errors in axonal pathfinding. Development 127:4061-4071.
40. Mancao M, Miller C, Cochrane B, Hoff C, Sauter K, Weber E (1998) Cerebrospinal fluid shunt infections in infants and children in Mobile, Alabama. Acta Paediatr 87:667-670.
41. Mandell JW, VandenBerg SR (1999) ERK/MAP kinase is chronically activated in human reactive astrocytes. NeuroReport 10:3567-3572.
42. Mangano FT, McAllister II JP, Jones HC, Johnson MJ, Kriebel RM (1998) The microglial response to progressive hydrocephalus in a model of inherited aqueductal stenosis. Neurol Res 20:697-704.
43. McAllister II JP, Mangano FT, Jones HC, Kriebel RM (1998) The microglial response in experimental infantile hydrocephalus. Eur J Pediatr Surg 8 [Suppl 1]:62.
44. Miller JM, Kumar R, McAllister II JP, Krause GS (2006) Gene expression analysis of the development of congenital hydrocephalus in the H-Tx rat. Brain Res 1075:36-47.
45. Miranda E, Almonacid JA, Rodriguez S, Perez J, Hein S, Cifuentes M, Fernandez-Llebrez P, Rodriguez EM (2001) Searching for specific binding sites of the secretory glycoproteins of the subcommissural organ. Microsc Res Tech 52:541-551.
46. Miyan JA, Khan MI, Kawarada Y, Sugiyama T, Bannister CM (1998) Cell death in the brain of the HTx rat. Eur J Pediatr Surg 8 [Suppl 1]:43-48.
47. Newberne PM (1962) The subcommissural organ of the vitamin B12-deficient rat. J Nutr 76:393-413.
48. Overholser MD, Whitley JR, O'Dell BL, Hogan AG (1954) The ventricular system in hydrocephalic rat brains produced by a deficiency of vitamin B12 or of folic acid in the maternal diet. Anat Rec 120:917-933.
49. Pascual O, Casper KB, Kubera C, Zhang J, Revilla-Sanchez R, Sul JY, Takano H, Moss SJ, McCarthy K, Haydon PG (2005) Astrocytic purinergic signaling coordinates synaptic networks. Science 310:113-116.
50. Pasti L, Zonta M, Pozzan T, Vicini S, Carmignoto G (2001) Cytosolic calcium oscillations in astrocytes may regulate exocytotic release of glutamate. J Neurosci 21:477-484.
51. Patwardhan RV, Nanda A (2005) Implanted ventricular shunts in the United States: the billion-dollar-a-year cost of hydrocephalus treatment. Neurosurgery 56:139-144; discussion 144-135.
52. Perez-Figares JM, Jimenez AJ, Perez-Martin M, Fernandez-Llebrez P, Cifuentes M, Riera P, Rodriguez S, Rodriguez EM (1998) Spontaneous congenital hydrocephalus in the mutant mouse hyh. Changes in the ventricular system and the subcommissural organ. J Neuropathol Exp Neurol 57:188-202.
53. Perez-Figares JM, Jimenez AJ, Rodriguez EM (2001) Subcommissural organ, cerebrospinal fluid circulation, and hydrocephalus. Microsc Res Tech 52:591-607.
54. Pople IK, Quinn MW, Bayston R (1990) Morbid and outcome of shunted hydrocephalus. Z Kinderchir 45 [Suppl 1]:29-31.
55. Porter JT, McCarthy KD (1996) Hippocampal astrocytes in situ respond to glutamate released from synaptic terminals. J Neurosci 16:5073-5081.
56. Redfern CH, Coward P, Degtyarev MY, Lee EK, Kwa AT, Hennighausen L, Bujard H, Fishman GI, Conklin BR (1999) Conditional expression and signaling of a specifically designed Gi-coupled receptor in transgenic mice. Nat Biotechnol 17:165-169.
57. Redfern CH, Degtyarev MY, Kwa AT, Salomonis N, Cotte N, Nanevicz T, Fidelman N, Desai K, Vranizan K, Lee EK, Coward P, Shah N, Warrington JA, Fishman GI, Bernstein D, Baker AJ, Conklin BR (2000) Conditional expression of a Gi-coupled receptor causes ventricular conduction delay and a lethal cardiomyopathy. Proc Natl Acad Sci USA 97:4826-4831.
58. Rodriguez-Perez LM, Perez-Martin M, Jimenez AJ, Fernandez-Llebrez P (2003) Immunocytochemical characterisation of the wall of the bovine lateral ventricle. Cell Tissue Res 314:325-335.
59. Sakakibara S, Nakamura Y, Yoshida T, Shibata S, Koike M, Takano H, Ueda S, Uchiyama Y, Noda T, Okano H (2002) RNA-binding protein Musashi family: roles for CNS stem cells and a subpopulation of ependymal cells revealed by targeted disruption and antisense ablation. Proc Natl Acad Sci USA 99:15194-15199.
60. Schmid RS, Pruitt WM, Maness PF (2000) A MAP kinase-signaling pathway mediates neurite outgrowth on L1 and requires Src-dependent endocytosis. J Neurosci 20:4177-4188.
61. Scott MA, Fletcher JM, Brookshire BL, Davidson KC, Landry SH, Bohan TC, Kramer LA, Brandt ME, Francis DJ (1998) Memory functions in children with early hydrocephalus. Neuropsychology 12:578-589.
62. Takahashi S, Makita Y, Okamoto N, Miyamoto A, Oki J (1997) L1CAM mutation in a Japanese family with X-linked hydrocephalus: a study for genetic counseling. Brain Dev 19:559-562.
63. Takahashi Y, Ohkura A, Hirohata M, Tokutomi T, Shigemori M (1998) Ultrastructure of obstructive tissue in malfunctioning ventricular catheters without infection. Neurol Med Chir (Tokyo) 38:399-404; discussion 403-394.
64. Takano T, Rutka JT, Becker LE (1996) Overexpression of nestin and vimentin in ependymal cells in hydrocephalus. Acta Neuropathol (Berl) 92:90-97.
65. Takeuchi IK, Takeuchi YK (1986) Congenital hydrocephalus following X-irradiation of pregnant rats on an early gestational day. Neurobehav Toxicol Teratol 8:143-150.
66. Wagner C, Batiz LF, Rodriguez S, Jimenez AJ, Paez P, Tome M, Perez-Figares JM, Rodriguez EM (2003) Cellular mechanisms involved in the stenosis and obliteration of the cerebral aqueduct of hyh mutant mice developing congenital hydrocephalus. J Neuropathol Exp Neurol 62:1019-1040.
67. Walz W (2000) Role of astrocytes in the clearance of excess extracellular potassium. Neurochem Int 36:291-300.
68. Yashon D, Jane JA, Sugar O (1965) The course of severe untreated infantile hydrocephalus. Prognostic significance of the cerebral mantle. J Neurosurg 23:509-516.