Pradofloxacin release from the OphthaCoil: A new device for sustained delivery of drugs to the eye

Journal of Drug Delivery Science and Technology

Volumn 17, Issue 1, 2007, Pages 87-91

  Pijls, R T ^a   Lindemann, S ^b   Nuijts, R M M A ^c   Daube, G W ^b   Koole, L H ^a,d  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b BAYER PHARMA AG   (Germany)

^c MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^d EINDHOVEN UNIVERSITY OF TECHNOLOGY   (Netherlands)

Author keywords

2 hydroxyethyl methacrylate; Conjunctival fornix; Drug release; Hydrogel; In vivo; Ocular insert; Quinolones

Indexed keywords

POLYMACON; PRADOFLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BACTERIUM; CONJUNCTIVITIS; CONTROLLED STUDY; DOG; DRUG DELIVERY SYSTEM; DRUG STRUCTURE; EYE; FEMALE; HYDROGEL; IN VITRO STUDY; IN VIVO STUDY; LACRIMAL FLUID; MALE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; OPHTHACOIL; SUSTAINED DRUG RELEASE;

EID: 33847367659     PISSN: 17732247     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1773-2247(07)50012-2     Document Type: Article

References (23)

1. Hosoya K., Lee V.H., Kim K.J. - Roles of the conjunctiva in ocular drug delivery: a review of conjunctival transport mechanisms and their regulation. - Eur J Pharm Biopharm, 60, 227-240, 2005.
2. Gulsen D., Chauhan A. - Ophthalmic drug delivery through contact lenses. - Invest Ophthalmol Vis Sci, 45, 2342-2347, 2004.
3. Le Bourlais C., Acar L., Zia H., Sado P.A., Needham T., Leverge R. - Ophthalmic drug delivery systems, Recent advances. - Prog Retin Eye Res, 17, 33-58, 1998.
4. Barbu E., Sarvaiya I., Green K.L., Nevell T.G., Tsibouklis J. - Vinylpyrrolidone-co-(meth)acrylic acid inserts for ocular drug delivery: Synthesis and evaluation. - J Biomed Mater Res A, 74, 598-606, 2005.
5. Kaur I.P., Kanwar M. - Ocular preparations: the formulation approach. - Drug Dev Ind Pharm, 28, 473-493, 2002.
6. Mah F.S. - Fourth-generation fluoroquinolones: new topical agents in the war on ocular bacterial infections. - Curr Opin Ophthalmol, 15, 316-320, 2004.
7. Mather R., Karenchak L.M., Romanowski E.G., Kowalski R.P. - Fourth generation fluoroquinolones: new weapons in the arsenal of ophthalmic antibiotics. - Am J Ophthalmol, 133, 463-466, 2002.
8. Linde H.J., Lehn N. - Mutant prevention concentration of nalidixic acid, ciprofloxacin, clinafloxacin, levofloxacin, norfloxacin, ofloxacin, sparfloxacin or trovafloxacin for Escherichia coli under different growth conditions. - J Antimicrob Chemother, 53, 252-257, 2004.
9. Pijls R.T., Hanssen H.H., Nuijts R.M., Koole L.H. - Flexible coils with a drug-releasing hydrophilic coating: A new platform for controlled delivery of drugs to the eye? - Biomed Mater Eng, 14, 383-393, 2004.
10. Pijls R.T., Sonderkamp T., Daube G.W., Krebber R., Hanssen H.H., Nuijts R.M., Koole L.H. - Studies on a new device for drug delivery to the eye. - Eur J Pharm Biopharm, 59, 283-288, 2005.
11. Aldenhoff Y.B., Knetsch M.L., Hanssen J.H., Lindhout T., Wielders S.J., Koole L.H. - Coils and tubes releasing heparin. Studies on a new vascular graft prototype. - Biomaterials, 25, 3125-3133, 2004.
12. Hanssen H.H., Wetzels G.M., Benzina A., van der Veen F.H., Lindhout T., Koole L.H. - Metallic wires with an adherent lubricious and blood-compatible polymeric coating and their use in the manufacture of novel slippery-when-wet guidewires: possible applications related to controlled local drug delivery. - J Biomed Mater Res, 48, 820-828, 1999.
13. Knetsch M.L., Aldenhoff Y.B., Schraven M., Koole L.H. - Human endothelial cell attachment and proliferation on a novel vascular graft prototype. - J Biomed Mater Res, 71A, 615-624, 2004.
14. Peerlings C.C., Hanssen H.H., Bevers R.T., Boelen E.J., Stelt B.J., Korthagen E.J., Koole L.H. - Heparin release from slippery-when-wet guide wires for intravascular use. - J Biomed Mater Res, 63, 692-698, 2002.
15. Wetzstein H.G. - Comparative mutant prevention concentrations of pradofloxacin and other veterinary fluoroquinolones indicate differing potentials in preventing selection of resistance. - Antimicrob Agents Chemother, 49, 4166-4173, 2005.
16. Gulsen D., Chauhan A. - Dispersion of microemulsion drops in HEMA hydrogel: a potential ophthalmic drug delivery vehicle. - Int J Pharm, 292, 95-117, 2005.
17. Ferreira L., Vidal M.M., Gil M.H. - Evaluation of poly(2-hydroxyethyl methacrylate) gels as drug delivery systems at different pH values. - Int J Pharm, 194, 169-180, 2000.
18. Kejlova K., Labsky J., Jirova D., Bendova H. - Hydrophilic polymers, Biocompatibility testing in vitro. - Toxicol In vitro, 19, 957-962, 2005.
19. Paulsson M., Edsman K. - Controlled drug release from gels using surfactant aggregates: I. Effect of lipophilic interactions for a series of uncharged substances. - J Pharm Sci, 90, 1216-1225, 2001.
20. Glasson M.J., Stapleton F., Keay L., Sweeney D., Willcox M.D. - Differences in clinical parameters and tear film of tolerant and intolerant contact lens wearers. - Invest Ophthalmol Vis Sci, 44, 5116-5124, 2003.
21. Baeyens V., Felt-Baeyens O., Rougier S., Pheulpin S., Boisrame B., Gurny R. - Clinical evaluation of bioadhesive ophthalmic drug inserts (BODI) for the treatment of external ocular infections in dogs. - J Control Release, 85, 163-168, 2002.
22. Baeyens V.V., Percicot C., Zignani M., Deshpande A.A., Kaltsatos V.V., Gurny R. - Ocular drug delivery in veterinary medicine. - Adv Drug Deliv Rev, 28, 335-361, 1997.
23. Gilger B. - Equine Ophthalmology. - Elsevier Saunders, 2005, pp. 313-314.