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Volumn 26, Issue 10, 2007, Pages 1417-1427

Basement membrane component laminin-5 is a target of the tumor suppressor Smad4

Author keywords

Basement membrane; Invasion; Laminin 5; TGF ; Tumor suppressor Smad4

Indexed keywords

KALININ; MEMBRANE PROTEIN; SMAD4 PROTEIN; TUMOR SUPPRESSOR PROTEIN;

EID: 33847346860     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1209918     Document Type: Article
Times cited : (31)

References (41)
  • 2
    • 0025854312 scopus 로고
    • Altered deposition of basementmembrane molecules in co-cultures of colonic cancer cells and fibroblasts
    • Bouziges F, Simo P, Simon-Assmann P, Haffen K, Kedinger M. (1991). Altered deposition of basementmembrane molecules in co-cultures of colonic cancer cells and fibroblasts. Int J Cancer 48: 101-108.
    • (1991) Int J Cancer , vol.48 , pp. 101-108
    • Bouziges, F.1    Simo, P.2    Simon-Assmann, P.3    Haffen, K.4    Kedinger, M.5
  • 3
    • 22144497081 scopus 로고    scopus 로고
    • Invasion and metastasis in colorectal cancer: Epithelial-mesenchymal transition, mesenchymal-epithelial transition, stem cells and betacatenin
    • Brabletz T, Hlubek F, Spaderna S, Schmalhofer O, Hiendlmeyer E, Jung A et al. (2005). Invasion and metastasis in colorectal cancer: epithelial-mesenchymal transition, mesenchymal-epithelial transition, stem cells and betacatenin. Cells Tissues Organs 179: 56-65.
    • (2005) Cells Tissues Organs , vol.179 , pp. 56-65
    • Brabletz, T.1    Hlubek, F.2    Spaderna, S.3    Schmalhofer, O.4    Hiendlmeyer, E.5    Jung, A.6
  • 4
    • 0035881472 scopus 로고    scopus 로고
    • Binding of c-Myc to chromatin mediates mitogen-induced acetylation of histone H4 and gene activation
    • Frank SR, Schroeder M, Fernandez P, Taubert S, Amati B. (2001). Binding of c-Myc to chromatin mediates mitogen-induced acetylation of histone H4 and gene activation. Genes Dev 15: 2069-2082.
    • (2001) Genes Dev , vol.15 , pp. 2069-2082
    • Frank, S.R.1    Schroeder, M.2    Fernandez, P.3    Taubert, S.4    Amati, B.5
  • 5
    • 0034858098 scopus 로고    scopus 로고
    • Biological and clinical relevanceof Laminin-5 in cancer
    • Giannelli G, Antonaci S. (2000). Biological and clinical relevanceof Laminin-5 in cancer. Clin Exp Metast 18: 439-443.
    • (2000) Clin Exp Metast , vol.18 , pp. 439-443
    • Giannelli, G.1    Antonaci, S.2
  • 7
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. (2000). The hallmarks of cancer. Cell 100: 57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 8
    • 0035890760 scopus 로고    scopus 로고
    • Expression of the invasion factor laminin gamma2 in colorectal carcinomas is regulated by beta-catenin
    • Hlubek F, Jung A, Kotzor N, Kirchner T, Brabletz T. (2001). Expression of the invasion factor laminin gamma2 in colorectal carcinomas is regulated by beta-catenin. Cancer Res 61: 8089-8093.
    • (2001) Cancer Res , vol.61 , pp. 8089-8093
    • Hlubek, F.1    Jung, A.2    Kotzor, N.3    Kirchner, T.4    Brabletz, T.5
  • 9
    • 11144356448 scopus 로고    scopus 로고
    • Proteomic analysis of the TGF-beta signaling pathway in pancreatic carcinoma cells using stable RNA interference to silence Smad4 expression
    • Imamura T, Kanai F, Kawakami T, Amarsanaa J, Ijichi H, Hoshida Y et al. (2004). Proteomic analysis of the TGF-beta signaling pathway in pancreatic carcinoma cells using stable RNA interference to silence Smad4 expression. Biochem Biophys Res Commun 318: 289-296.
    • (2004) Biochem Biophys Res Commun , vol.318 , pp. 289-296
    • Imamura, T.1    Kanai, F.2    Kawakami, T.3    Amarsanaa, J.4    Ijichi, H.5    Hoshida, Y.6
  • 10
    • 19944434193 scopus 로고    scopus 로고
    • Smad4 silencing in pancreatic cancer cell lines using stable RNA interference and gene expression profiles induced by transforming growth factor-beta
    • Jazag A, Ijichi H, Kanai F, Imamura T, Guleng B, Ohta M et al. (2005). Smad4 silencing in pancreatic cancer cell lines using stable RNA interference and gene expression profiles induced by transforming growth factor-beta. Oncogene 24: 662-671.
    • (2005) Oncogene , vol.24 , pp. 662-671
    • Jazag, A.1    Ijichi, H.2    Kanai, F.3    Imamura, T.4    Guleng, B.5    Ohta, M.6
  • 12
    • 16544391155 scopus 로고    scopus 로고
    • Laminin-5 in epithelial tumour invasion
    • Katayama M, Sekiguchi K. (2004). Laminin-5 in epithelial tumour invasion. J Mol Histol 35: 277-286.
    • (2004) J Mol Histol , vol.35 , pp. 277-286
    • Katayama, M.1    Sekiguchi, K.2
  • 13
    • 0029082448 scopus 로고
    • Differential cytokine modulation of the genes LAMA3, LAMB3, and LAMC2, encoding the constitutive polypeptides, alpha 3, beta 3, and gamma 2, of human laminin 5 in epidermal keratinocytes
    • Korang K, Christiano AM, Uitto J, Mauviel A. (1995). Differential cytokine modulation of the genes LAMA3, LAMB3, and LAMC2, encoding the constitutive polypeptides, alpha 3, beta 3, and gamma 2, of human laminin 5 in epidermal keratinocytes. FEBS Lett 368: 556-558.
    • (1995) FEBS Lett , vol.368 , pp. 556-558
    • Korang, K.1    Christiano, A.M.2    Uitto, J.3    Mauviel, A.4
  • 14
    • 0035902141 scopus 로고    scopus 로고
    • The microenvironment of the tumour-host interface
    • Liotta LA, Kohn EC. (2001). The microenvironment of the tumour-host interface. Nature 411: 375-379.
    • (2001) Nature , vol.411 , pp. 375-379
    • Liotta, L.A.1    Kohn, E.C.2
  • 15
    • 0035892362 scopus 로고    scopus 로고
    • Laminin-5 in theprogre ssion of carcinomas
    • Lohi J. (2001). Laminin-5 in theprogre ssion of carcinomas. Int J Cancer 94: 763-767.
    • (2001) Int J Cancer , vol.94 , pp. 763-767
    • Lohi, J.1
  • 16
    • 0035745146 scopus 로고    scopus 로고
    • Immunohistochemical distribution of laminin-5 gamma2 chain and its developmental change in human embryonic and foetal tissues
    • Lu W, Miyazaki K, Mizushima H, Nemoto N. (2001). Immunohistochemical distribution of laminin-5 gamma2 chain and its developmental change in human embryonic and foetal tissues. Histochem J 33: 629-637.
    • (2001) Histochem J , vol.33 , pp. 629-637
    • Lu, W.1    Miyazaki, K.2    Mizushima, H.3    Nemoto, N.4
  • 17
    • 0035004797 scopus 로고    scopus 로고
    • Allelic loss is often thefirst hit in thebialle lic inactivation of the p53 and DPC4 genes during pancreatic carcinogenesis
    • Luettges J, Galehdari H, Bröcker V, Schwarte-Waldhoff I, Henne-Bruns D, Klöppel G et al. (2001). Allelic loss is often thefirst hit in thebialle lic inactivation of the p53 and DPC4 genes during pancreatic carcinogenesis. Am J Pathol 158: 1677-1683.
    • (2001) Am J Pathol , vol.158 , pp. 1677-1683
    • Luettges, J.1    Galehdari, H.2    Bröcker, V.3    Schwarte-Waldhoff, I.4    Henne-Bruns, D.5    Klöppel, G.6
  • 18
    • 0032211804 scopus 로고    scopus 로고
    • ECM signalling: Orchestrating cell behaviour and misbehaviour
    • Lukashev ME, Werb Z. (1998). ECM signalling: orchestrating cell behaviour and misbehaviour. Trends Cell Biol 8: 437-441.
    • (1998) Trends Cell Biol , vol.8 , pp. 437-441
    • Lukashev, M.E.1    Werb, Z.2
  • 19
    • 0033814963 scopus 로고    scopus 로고
    • Loss of dpc4 expression in colonic adenocarcinomas correlates with the presence of metastatic disease
    • Maitra A, Molberg K, Albores-Saavedra J, Lindberg G. (2000). Loss of dpc4 expression in colonic adenocarcinomas correlates with the presence of metastatic disease. Am J Pathol 157: 1105-1111.
    • (2000) Am J Pathol , vol.157 , pp. 1105-1111
    • Maitra, A.1    Molberg, K.2    Albores-Saavedra, J.3    Lindberg, G.4
  • 20
    • 0033587156 scopus 로고    scopus 로고
    • Higher frequency of Smad4 gene mutation in human colorectal cancer with distant metastasis
    • Miyaki M, Iijima T, Konishi M, Sakai K, Ishii A, Yasuno M et al. (1999). Higher frequency of Smad4 gene mutation in human colorectal cancer with distant metastasis. Oncogene 18: 3098-3103.
    • (1999) Oncogene , vol.18 , pp. 3098-3103
    • Miyaki, M.1    Iijima, T.2    Konishi, M.3    Sakai, K.4    Ishii, A.5    Yasuno, M.6
  • 21
    • 0031866379 scopus 로고    scopus 로고
    • Widedistribution of laminin-5 gamma 2 chain in basement membranes of various human tissues
    • Mizushima H, Koshikawa N, Moriyama K, Takamura H, Nagashima Y, Hirahara F et al. (1998). Widedistribution of laminin-5 gamma 2 chain in basement membranes of various human tissues. Horm Res 50(Suppl 2): 7-14.
    • (1998) Horm Res , vol.50 , Issue.SUPPL. 2 , pp. 7-14
    • Mizushima, H.1    Koshikawa, N.2    Moriyama, K.3    Takamura, H.4    Nagashima, Y.5    Hirahara, F.6
  • 22
    • 0037026605 scopus 로고    scopus 로고
    • Smad4 induces the tumor suppressor E-cadherin and P-cadherin in colon carcinoma cells
    • Muller N, Reinacher-Schick A, Baldus S, van Hengel J, Berx G, Baar A et al. (2002). Smad4 induces the tumor suppressor E-cadherin and P-cadherin in colon carcinoma cells. Oncogene 21: 6049-6058.
    • (2002) Oncogene , vol.21 , pp. 6049-6058
    • Muller, N.1    Reinacher-Schick, A.2    Baldus, S.3    van Hengel, J.4    Berx, G.5    Baar, A.6
  • 23
    • 0242380798 scopus 로고    scopus 로고
    • Converging signals synergistically activateth eLA MC2 promoter and lead to accumulation of thela minin gamma 2 chain in human colon carcinoma cells
    • Olsen J, Kirkeby LT, BrorssonMM, Dabelsteen S, Troelsen JT, Bordoy R et al. (2003). Converging signals synergistically activateth eLA MC2 promoter and lead to accumulation of thela minin gamma 2 chain in human colon carcinoma cells. Biochem J 371: 211-221.
    • (2003) Biochem J , vol.371 , pp. 211-221
    • Olsen, J.1    Kirkeby, L.T.2    Brorsson, M.M.3    Dabelsteen, S.4    Troelsen, J.T.5    Bordoy, R.6
  • 24
    • 0035988822 scopus 로고    scopus 로고
    • Laminin isoforms in tumor invasion, angiogenesis and metastasis
    • Patarroyo M, Tryggvason K, Virtanen I. (2002). Laminin isoforms in tumor invasion, angiogenesis and metastasis. Semin Cancer Biol 12: 197-207.
    • (2002) Semin Cancer Biol , vol.12 , pp. 197-207
    • Patarroyo, M.1    Tryggvason, K.2    Virtanen, I.3
  • 25
    • 0028173385 scopus 로고
    • The gamma 2 chain of kalinin/laminin 5 is preferentially expressed in invading malignant cells in human cancers
    • Pyke C, Romer J, Kallunki P, Lund LR, Ralfkiaer E, Dano K et al. (1994). The gamma 2 chain of kalinin/laminin 5 is preferentially expressed in invading malignant cells in human cancers. Am J Pathol 145: 782-791.
    • (1994) Am J Pathol , vol.145 , pp. 782-791
    • Pyke, C.1    Romer, J.2    Kallunki, P.3    Lund, L.R.4    Ralfkiaer, E.5    Dano, K.6
  • 26
    • 0029144854 scopus 로고
    • Laminin-5 is a marker of invading cancer cells in some human carcinomas and is coexpressed with the receptor for urokinase plasminogen activator in budding cancer cells in colon adenocarcinomas
    • Pyke C, Salo S, Ralfkiaer E, Romer J, Dano K, Tryggvason K. (1995). Laminin-5 is a marker of invading cancer cells in some human carcinomas and is coexpressed with the receptor for urokinase plasminogen activator in budding cancer cells in colon adenocarcinomas. Cancer Res 55: 4132-4139.
    • (1995) Cancer Res , vol.55 , pp. 4132-4139
    • Pyke, C.1    Salo, S.2    Ralfkiaer, E.3    Romer, J.4    Dano, K.5    Tryggvason, K.6
  • 27
    • 0036710163 scopus 로고    scopus 로고
    • Cells obtained from colorectal microadenomas mirror early premalignant growth patterns in vitro
    • Richter M, Jurek D, Wrba F, Kaserer K, Wurzer G, Karner-Hanusch J et al. (2002). Cells obtained from colorectal microadenomas mirror early premalignant growth patterns in vitro. Eur J Cancer 38: 1937-1945.
    • (2002) Eur J Cancer , vol.38 , pp. 1937-1945
    • Richter, M.1    Jurek, D.2    Wrba, F.3    Kaserer, K.4    Wurzer, G.5    Karner-Hanusch, J.6
  • 28
    • 0033587016 scopus 로고    scopus 로고
    • DPC4/SMAD4 mediated tumor suppression of colon carcinoma cells is associated with reduced urokinase expression
    • Schwarte-Waldhoff I, Klein S, Blass-Kampmann S, Hintelmann A, Eilert C, Dreschers S et al. (1999). DPC4/SMAD4 mediated tumor suppression of colon carcinoma cells is associated with reduced urokinase expression. Oncogene 18: 3152-3158.
    • (1999) Oncogene , vol.18 , pp. 3152-3158
    • Schwarte-Waldhoff, I.1    Klein, S.2    Blass-Kampmann, S.3    Hintelmann, A.4    Eilert, C.5    Dreschers, S.6
  • 31
    • 0031782155 scopus 로고    scopus 로고
    • Differential expression of laminin-5 subunits and integrin receptors in human colorectal neoplasia
    • Sordat I, Bosman FT, Dorta G, Rousselle P, Aberdam D, Blum AL et al. (1998). Differential expression of laminin-5 subunits and integrin receptors in human colorectal neoplasia. J Pathol 185: 44-52.
    • (1998) J Pathol , vol.185 , pp. 44-52
    • Sordat, I.1    Bosman, F.T.2    Dorta, G.3    Rousselle, P.4    Aberdam, D.5    Blum, A.L.6
  • 32
    • 0034568845 scopus 로고    scopus 로고
    • Tumor cell budding and laminin-5 expression in colorectal carcinoma can be modulated by the tissue micro-environment
    • Sordat I, Rousselle P, Chaubert P, Petermann O, Aberdam D, Bosman FT et al. (2000). Tumor cell budding and laminin-5 expression in colorectal carcinoma can be modulated by the tissue micro-environment. Int J Cancer 88: 708-717.
    • (2000) Int J Cancer , vol.88 , pp. 708-717
    • Sordat, I.1    Rousselle, P.2    Chaubert, P.3    Petermann, O.4    Aberdam, D.5    Bosman, F.T.6
  • 33
    • 2542532413 scopus 로고    scopus 로고
    • Biologically different subgroups of invasiveductal carcinoma of thepancre as: Dpc4 status according to theratio of intraductal carcinoma components
    • Takahashi H, Oda T, Hasebe T, Aoyagi Y, Kinoshita T, Konishi M et al. (2004). Biologically different subgroups of invasiveductal carcinoma of thepancre as: Dpc4 status according to theratio of intraductal carcinoma components. Clin Cancer Res 10: 3772-3779.
    • (2004) Clin Cancer Res , vol.10 , pp. 3772-3779
    • Takahashi, H.1    Oda, T.2    Hasebe, T.3    Aoyagi, Y.4    Kinoshita, T.5    Konishi, M.6
  • 34
    • 0037086455 scopus 로고    scopus 로고
    • Cytoplasmic expression of laminin gamma2 chain correlates with postoperative hepatic metastasis and poor prognosis in patients with pancreatic ductal adenocarcinoma
    • Takahashi S, Hasebe T, Oda T, Sasaki S, Kinoshita T, Konishi M et al. (2002). Cytoplasmic expression of laminin gamma2 chain correlates with postoperative hepatic metastasis and poor prognosis in patients with pancreatic ductal adenocarcinoma. Cancer 94: 1894-1901.
    • (2002) Cancer , vol.94 , pp. 1894-1901
    • Takahashi, S.1    Hasebe, T.2    Oda, T.3    Sasaki, S.4    Kinoshita, T.5    Konishi, M.6
  • 35
    • 0032489508 scopus 로고    scopus 로고
    • Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes
    • Takaku K, Oshima M, Miyoshi H, Matsui M, Seldin MF, Taketo MM. (1998). Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes. Cell 92: 645-656.
    • (1998) Cell , vol.92 , pp. 645-656
    • Takaku, K.1    Oshima, M.2    Miyoshi, H.3    Matsui, M.4    Seldin, M.F.5    Taketo, M.M.6
  • 36
    • 85012563489 scopus 로고    scopus 로고
    • Interactions between laminin and epithelial cells in intestinal health and disease
    • Teller IC, Beaulieu JF. (2001). Interactions between laminin and epithelial cells in intestinal health and disease. Expert Rev Mol Med 2001: 1-18.
    • (2001) Expert Rev Mol Med , vol.2001 , pp. 1-18
    • Teller, I.C.1    Beaulieu, J.F.2
  • 37
    • 0036595629 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in tumour progression
    • Thiery JP. (2002). Epithelial-mesenchymal transitions in tumour progression. Nat Rev Cancer 2: 442-454.
    • (2002) Nat Rev Cancer , vol.2 , pp. 442-454
    • Thiery, J.P.1
  • 38
    • 2442471740 scopus 로고    scopus 로고
    • Tumor suppressor Smad4 mediates downregulation of the anti-adhesive invasion-promoting matricellular protein SPARC: Landscaping activity of Smad4 as revealed by a 'secretome' analysis
    • Volmer MW, Radacz Y, Hahn SA, Klein-Scory S, Stuhler K, Zapatka M et al. (2004). Tumor suppressor Smad4 mediates downregulation of the anti-adhesive invasion-promoting matricellular protein SPARC: landscaping activity of Smad4 as revealed by a 'secretome' analysis. Proteomics 4: 1324-1334.
    • (2004) Proteomics , vol.4 , pp. 1324-1334
    • Volmer, M.W.1    Radacz, Y.2    Hahn, S.A.3    Klein-Scory, S.4    Stuhler, K.5    Zapatka, M.6
  • 39
    • 0027278234 scopus 로고
    • Epiligrin, a component of epithelial basement membranes, is an adhesive ligand for alpha 3 beta 1 positive T lymphocytes
    • Wayner EA, Gil SG, Murphy GF, Wilke MS, Carter WG. (1993). Epiligrin, a component of epithelial basement membranes, is an adhesive ligand for alpha 3 beta 1 positive T lymphocytes. J Cell Biol 121: 1141-1152.
    • (1993) J Cell Biol , vol.121 , pp. 1141-1152
    • Wayner, E.A.1    Gil, S.G.2    Murphy, G.F.3    Wilke, M.S.4    Carter, W.G.5
  • 40
    • 0034032009 scopus 로고    scopus 로고
    • Loss of expression of Dpc4 in pancreatic intraepithelial neoplasia: Evidence that DPC4 inactivation occurs late in neoplastic progression
    • Wilentz RE, Iacobuzio-Donahue CA, Argani P, McCarthy DM, Parsons JL, Yeo CJ et al. (2000). Loss of expression of Dpc4 in pancreatic intraepithelial neoplasia: evidence that DPC4 inactivation occurs late in neoplastic progression. Cancer Res 60: 2002-2006.
    • (2000) Cancer Res , vol.60 , pp. 2002-2006
    • Wilentz, R.E.1    Iacobuzio-Donahue, C.A.2    Argani, P.3    McCarthy, D.M.4    Parsons, J.L.5    Yeo, C.J.6
  • 41
    • 23944523378 scopus 로고    scopus 로고
    • Suppression of laminin-5 expression leads to increased motility, tumorigenicity, and invasion
    • Yuen HW, Ziober AF, Gopal P, Nasrallah I, Falls EM, Meneguzzi G et al. (2005). Suppression of laminin-5 expression leads to increased motility, tumorigenicity, and invasion. Exp Cell Res 309: 198-210.
    • (2005) Exp Cell Res , vol.309 , pp. 198-210
    • Yuen, H.W.1    Ziober, A.F.2    Gopal, P.3    Nasrallah, I.4    Falls, E.M.5    Meneguzzi, G.6


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