The function neutralizing anti-TrkA antibody MNAC13 reduces inflammatory and neuropathic pain

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 8, 2007, Pages 2985-2990

  Ugolini, Gabriele ^a   Marinelli, Sara ^a,b   Covaceuszach, Sonia ^a   Cattaneo, Antonino ^a,c   Pavone, Flaminia ^b  

^a Lay Line Genomics SpA   (Italy)

^b CNR   (Italy)

^c EUROPEAN BRAIN RESEARCH INSTITUTE   (Italy)

Author keywords

Analgesia; Behavior; Mice; Nerve growth factor

Indexed keywords

17 METHYLNALOXONE; FORMALDEHYDE; IMMUNOGLOBULIN G; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY MNAC13; NERVE GROWTH FACTOR; OPIATE ANTAGONIST; PHOSPHOLIPASE C GAMMA; PROTEIN TYROSINE KINASE A; UNCLASSIFIED DRUG;

ANALGESIA; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHRONIC PAIN; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENTIATION; ENZYME PHOSPHORYLATION; INFLAMMATION; MOUSE; NEUROPATHIC PAIN; NONHUMAN; PAIN; PRIORITY JOURNAL; SURFACE PLASMON RESONANCE;

3T3 CELLS; ANALGESICS, OPIOID; ANIMALS; ANTIBODIES, MONOCLONAL; BINDING SITES, ANTIBODY; DISEASE MODELS, ANIMAL; FORMALDEHYDE; HUMANS; INFLAMMATION; MALE; MICE; MICE, INBRED BALB C; NERVE GROWTH FACTOR; NEUTRALIZATION TESTS; PAIN; RECEPTOR, TRKA; SIGNAL TRANSDUCTION;

MUS;

EID: 33847325329     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0611253104     Document Type: Article

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