-
1
-
-
33746729791
-
Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research
-
Gold R., Linington C., and Lassmann H. Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research. Brain 129 (2006) 1953-1971
-
(2006)
Brain
, vol.129
, pp. 1953-1971
-
-
Gold, R.1
Linington, C.2
Lassmann, H.3
-
2
-
-
0038823638
-
Gene therapy in autoimmune, demyelinating disease of the central nervous system
-
Baker D., and Hankey D.J. Gene therapy in autoimmune, demyelinating disease of the central nervous system. Gene Ther. 10 (2003) 844-853
-
(2003)
Gene Ther.
, vol.10
, pp. 844-853
-
-
Baker, D.1
Hankey, D.J.2
-
3
-
-
0028152937
-
Transforming growth factor beta: the good, the bad, and the ugly
-
Wahl S.M. Transforming growth factor beta: the good, the bad, and the ugly. J. Exp. Med. 180 (1994) 1587-1590
-
(1994)
J. Exp. Med.
, vol.180
, pp. 1587-1590
-
-
Wahl, S.M.1
-
4
-
-
0037407769
-
Genealogy, expression, and cellular function of transforming growth factor-beta
-
Govinden R., and Bhoola K.D. Genealogy, expression, and cellular function of transforming growth factor-beta. Pharmacol. Ther. 98 (2003) 257-265
-
(2003)
Pharmacol. Ther.
, vol.98
, pp. 257-265
-
-
Govinden, R.1
Bhoola, K.D.2
-
5
-
-
0037013930
-
Mechanism of transforming growth factor beta-induced inhibition of T helper type 1 differentiation
-
Gorelik L., Constant S., and Flavell R.A. Mechanism of transforming growth factor beta-induced inhibition of T helper type 1 differentiation. J. Exp. Med. 195 (2002) 1499-1505
-
(2002)
J. Exp. Med.
, vol.195
, pp. 1499-1505
-
-
Gorelik, L.1
Constant, S.2
Flavell, R.A.3
-
6
-
-
0034121583
-
When engineered to produce latent TGF-beta1, antigen specific T cells down regulate Th1 cell-mediated autoimmune and Th2 cell-mediated allergic inflammatory processes
-
Thorbecke G.J., Umetsu D.T., deKruyff R.H., Hansen G., Chen L.Z., and Hochwald G.M. When engineered to produce latent TGF-beta1, antigen specific T cells down regulate Th1 cell-mediated autoimmune and Th2 cell-mediated allergic inflammatory processes. Cytokine Growth Factor Rev. 11 (2000) 89-96
-
(2000)
Cytokine Growth Factor Rev.
, vol.11
, pp. 89-96
-
-
Thorbecke, G.J.1
Umetsu, D.T.2
deKruyff, R.H.3
Hansen, G.4
Chen, L.Z.5
Hochwald, G.M.6
-
7
-
-
0026006736
-
Successful treatment of experimental allergic encephalomyelitis with transforming growth factor-beta 1
-
Johns L.D., Flanders K.C., Ranges G.E., and Sriram S. Successful treatment of experimental allergic encephalomyelitis with transforming growth factor-beta 1. J. Immunol. 147 (1991) 1792-1796
-
(1991)
J. Immunol.
, vol.147
, pp. 1792-1796
-
-
Johns, L.D.1
Flanders, K.C.2
Ranges, G.E.3
Sriram, S.4
-
8
-
-
0033543127
-
Prevention of experimental allergic encephalomyelitis by intramuscular gene transfer with cytokine-encoding plasmid vectors
-
Piccirillo C.A., and Prud'homme G.J. Prevention of experimental allergic encephalomyelitis by intramuscular gene transfer with cytokine-encoding plasmid vectors. Hum. Gene Ther. 10 (1999) 1915-1922
-
(1999)
Hum. Gene Ther.
, vol.10
, pp. 1915-1922
-
-
Piccirillo, C.A.1
Prud'homme, G.J.2
-
9
-
-
0033953109
-
The inhibitory effects of transforming growth factor-beta-1 (TGF-beta1) in autoimmune diseases
-
Prud'homme G.J., and Piccirillo C.A. The inhibitory effects of transforming growth factor-beta-1 (TGF-beta1) in autoimmune diseases. J. Autoimmun. 14 (2000) 23-42
-
(2000)
J. Autoimmun.
, vol.14
, pp. 23-42
-
-
Prud'homme, G.J.1
Piccirillo, C.A.2
-
10
-
-
0025892475
-
Prevention and treatment of chronic relapsing experimental allergic encephalomyelitis by transforming growth factor-beta 1
-
Racke M.K., Dhib-Jalbut S., Cannella B., Albert P.S., Raine C.S., and McFarlin D.E. Prevention and treatment of chronic relapsing experimental allergic encephalomyelitis by transforming growth factor-beta 1. J. Immunol. 146 (1991) 3012-3017
-
(1991)
J. Immunol.
, vol.146
, pp. 3012-3017
-
-
Racke, M.K.1
Dhib-Jalbut, S.2
Cannella, B.3
Albert, P.S.4
Raine, C.S.5
McFarlin, D.E.6
-
11
-
-
0027313082
-
Studies on the mechanisms by which transforming growth factor-beta (TGF-β) protects against allergic encephalomyelitis. Antagonism between TGF-β and tumor necrosis factor
-
Santambrogio L., Hochwald G.M., Saxena B., Leu C.H., Martz J.E., Carlino J.A., Ruddle N.H., Palladino M.A., Gold L.I., and Thorbecke G.J. Studies on the mechanisms by which transforming growth factor-beta (TGF-β) protects against allergic encephalomyelitis. Antagonism between TGF-β and tumor necrosis factor. J. Immunol. 151 (1993) 1116-1127
-
(1993)
J. Immunol.
, vol.151
, pp. 1116-1127
-
-
Santambrogio, L.1
Hochwald, G.M.2
Saxena, B.3
Leu, C.H.4
Martz, J.E.5
Carlino, J.A.6
Ruddle, N.H.7
Palladino, M.A.8
Gold, L.I.9
Thorbecke, G.J.10
-
12
-
-
0141994811
-
Transforming growth factor-beta 1-mediated neuroprotection against excitotoxic injury in vivo
-
Boche D., Cunningham C., Gauldie J., and Perry V.H. Transforming growth factor-beta 1-mediated neuroprotection against excitotoxic injury in vivo. J. Cereb. Blood Flow Metab. 23 (2003) 1174-1182
-
(2003)
J. Cereb. Blood Flow Metab.
, vol.23
, pp. 1174-1182
-
-
Boche, D.1
Cunningham, C.2
Gauldie, J.3
Perry, V.H.4
-
13
-
-
0037095746
-
Transforming growth factor-beta 1 increases bad phosphorylation and protects neurons against damage
-
Zhu Y., Yang G.Y., Ahlemeyer B., Pang L., Che X.M., Culmsee C., Klumpp S., and Krieglstein J. Transforming growth factor-beta 1 increases bad phosphorylation and protects neurons against damage. J. Neurosci. 22 (2002) 3898-3909
-
(2002)
J. Neurosci.
, vol.22
, pp. 3898-3909
-
-
Zhu, Y.1
Yang, G.Y.2
Ahlemeyer, B.3
Pang, L.4
Che, X.M.5
Culmsee, C.6
Klumpp, S.7
Krieglstein, J.8
-
14
-
-
0345412011
-
FGF-2 and PDGF-AA in a myelination of CNS aggregate cultures enriched with macrophages
-
Diemel L.T., Jackson S.J., Cuzner M.L., and TGF-beta1 R.f. FGF-2 and PDGF-AA in a myelination of CNS aggregate cultures enriched with macrophages. J. Neurosci. Res. 74 (2003) 858-867
-
(2003)
J. Neurosci. Res.
, vol.74
, pp. 858-867
-
-
Diemel, L.T.1
Jackson, S.J.2
Cuzner, M.L.3
TGF-beta1, R.f.4
-
15
-
-
0031866885
-
Phase 1 trial of transforming growth factor beta 2 in chronic progressive MS
-
Calabresi P.A., Fields N.S., Maloni H.W., Hanham A., Carlino J., Moore J., Levin M.C., Dhib-Jalbut S., Tranquill L.R., Austin H., McFarland H.F., and Racke M.K. Phase 1 trial of transforming growth factor beta 2 in chronic progressive MS. Neurology 51 (1998) 289-292
-
(1998)
Neurology
, vol.51
, pp. 289-292
-
-
Calabresi, P.A.1
Fields, N.S.2
Maloni, H.W.3
Hanham, A.4
Carlino, J.5
Moore, J.6
Levin, M.C.7
Dhib-Jalbut, S.8
Tranquill, L.R.9
Austin, H.10
McFarland, H.F.11
Racke, M.K.12
-
16
-
-
0344522704
-
A novel neurotropic expression vector based on the avirulent A7(74) strain of Semliki Forest virus
-
Vähä-Koskela M.J., Tuittila M.T., Nygårdas P.T., Nyman J.K., Ehrengruber M.U., Renggli M., and Hinkkanen A.E. A novel neurotropic expression vector based on the avirulent A7(74) strain of Semliki Forest virus. J. Neurovirol. 9 (2003) 1-15
-
(2003)
J. Neurovirol.
, vol.9
, pp. 1-15
-
-
Vähä-Koskela, M.J.1
Tuittila, M.T.2
Nygårdas, P.T.3
Nyman, J.K.4
Ehrengruber, M.U.5
Renggli, M.6
Hinkkanen, A.E.7
-
17
-
-
4944246703
-
Treatment of experimental autoimmune encephalomyelitis with a neurotropic alphavirus vector expressing tissue inhibitor of metalloproteinase-2
-
Nygårdas P.T., Grönberg S.A., Heikkilä J., Joronen K., Sorsa T., and Hinkkanen A.E. Treatment of experimental autoimmune encephalomyelitis with a neurotropic alphavirus vector expressing tissue inhibitor of metalloproteinase-2. Scand. J. Immunol. 60 (2004) 372-381
-
(2004)
Scand. J. Immunol.
, vol.60
, pp. 372-381
-
-
Nygårdas, P.T.1
Grönberg, S.A.2
Heikkilä, J.3
Joronen, K.4
Sorsa, T.5
Hinkkanen, A.E.6
-
18
-
-
33746917920
-
Oncolytic capacity of attenuated replicative semliki forest virus in human melanoma xenografts in severe combined immunodeficient mice
-
Vähä-Koskela M.J., Kallio J.P., Jansson L.C., Heikkilä J.E., Zakhartchenko V.A., Kallajoki M.A., Kähäri V.M., and Hinkkanen A.E. Oncolytic capacity of attenuated replicative semliki forest virus in human melanoma xenografts in severe combined immunodeficient mice. Cancer Res. 66 (2006) 7185-7194
-
(2006)
Cancer Res.
, vol.66
, pp. 7185-7194
-
-
Vähä-Koskela, M.J.1
Kallio, J.P.2
Jansson, L.C.3
Heikkilä, J.E.4
Zakhartchenko, V.A.5
Kallajoki, M.A.6
Kähäri, V.M.7
Hinkkanen, A.E.8
-
19
-
-
28444468799
-
Statistical analysis of data from studies on experimental autoimmune encephalomyelitis
-
Fleming K.K., Bovaird J.A., Mosier M.C., Emerson M.R., LeVine S.M., and Marquis J.G. Statistical analysis of data from studies on experimental autoimmune encephalomyelitis. J. Neuroimmunol. 170 (2005) 71-84
-
(2005)
J. Neuroimmunol.
, vol.170
, pp. 71-84
-
-
Fleming, K.K.1
Bovaird, J.A.2
Mosier, M.C.3
Emerson, M.R.4
LeVine, S.M.5
Marquis, J.G.6
-
20
-
-
0024312217
-
Site-directed mutagenesis of cysteine residues in the pro region of the transforming growth factor beta 1 precursor. Expression and characterization of mutant proteins
-
Brunner A.M., Marquardt H., Malacko A.R., Lioubin M.N., and Purchio A.F. Site-directed mutagenesis of cysteine residues in the pro region of the transforming growth factor beta 1 precursor. Expression and characterization of mutant proteins. J. Biol. Chem. 264 (1989) 13660-13664
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 13660-13664
-
-
Brunner, A.M.1
Marquardt, H.2
Malacko, A.R.3
Lioubin, M.N.4
Purchio, A.F.5
-
21
-
-
33646560950
-
Transforming growth factor-beta induces development of the T(H)17 lineage
-
Mangan P.R., Harrington L.E., O'Quinn D.B., Helms W.S., Bullard D.C., Elson C.O., Hatton R.D., Wahl S.M., Schoeb T.R., and Weaver C.T. Transforming growth factor-beta induces development of the T(H)17 lineage. Nature 441 (2006) 231-234
-
(2006)
Nature
, vol.441
, pp. 231-234
-
-
Mangan, P.R.1
Harrington, L.E.2
O'Quinn, D.B.3
Helms, W.S.4
Bullard, D.C.5
Elson, C.O.6
Hatton, R.D.7
Wahl, S.M.8
Schoeb, T.R.9
Weaver, C.T.10
-
22
-
-
0346025622
-
Effect of intranasal administration of Semliki Forest virus recombinant particles expressing reporter and cytokine genes on the progression of experimental autoimmune encephalomyelitis
-
Jerusalmi A., Morris-Downes M.M., Sheahan B.J., and Atkins G.J. Effect of intranasal administration of Semliki Forest virus recombinant particles expressing reporter and cytokine genes on the progression of experimental autoimmune encephalomyelitis. Mol. Ther. 8 (2003) 886-894
-
(2003)
Mol. Ther.
, vol.8
, pp. 886-894
-
-
Jerusalmi, A.1
Morris-Downes, M.M.2
Sheahan, B.J.3
Atkins, G.J.4
-
23
-
-
32944474703
-
CNS gene therapy applications of the Semliki Forest virus 1 vector are limited by neurotoxicity
-
Graham A., Walker R., Baird P., Hahn C.N., and Fazakerley J.K. CNS gene therapy applications of the Semliki Forest virus 1 vector are limited by neurotoxicity. Mol. Ther. 13 (2006) 631-635
-
(2006)
Mol. Ther.
, vol.13
, pp. 631-635
-
-
Graham, A.1
Walker, R.2
Baird, P.3
Hahn, C.N.4
Fazakerley, J.K.5
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