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Volumn 355, Issue 3, 2007, Pages 776-781

Semliki Forest virus vectors expressing transforming growth factor beta inhibit experimental autoimmune encephalomyelitis in Balb/c mice

Author keywords

Central nervous system (CNS); Experimental autoimmune encephalomyelitis (EAE); Gene therapy; Semliki Forest virus (SFV); Transforming growth factor beta 1 (TGF 1)

Indexed keywords

LUCIFERASE; MESSENGER RNA; PLASMINOGEN ACTIVATOR INHIBITOR 1; TRANSFORMING GROWTH FACTOR BETA1; VIRUS VECTOR;

EID: 33847265305     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.02.026     Document Type: Article
Times cited : (11)

References (23)
  • 1
    • 33746729791 scopus 로고    scopus 로고
    • Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research
    • Gold R., Linington C., and Lassmann H. Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research. Brain 129 (2006) 1953-1971
    • (2006) Brain , vol.129 , pp. 1953-1971
    • Gold, R.1    Linington, C.2    Lassmann, H.3
  • 2
    • 0038823638 scopus 로고    scopus 로고
    • Gene therapy in autoimmune, demyelinating disease of the central nervous system
    • Baker D., and Hankey D.J. Gene therapy in autoimmune, demyelinating disease of the central nervous system. Gene Ther. 10 (2003) 844-853
    • (2003) Gene Ther. , vol.10 , pp. 844-853
    • Baker, D.1    Hankey, D.J.2
  • 3
    • 0028152937 scopus 로고
    • Transforming growth factor beta: the good, the bad, and the ugly
    • Wahl S.M. Transforming growth factor beta: the good, the bad, and the ugly. J. Exp. Med. 180 (1994) 1587-1590
    • (1994) J. Exp. Med. , vol.180 , pp. 1587-1590
    • Wahl, S.M.1
  • 4
    • 0037407769 scopus 로고    scopus 로고
    • Genealogy, expression, and cellular function of transforming growth factor-beta
    • Govinden R., and Bhoola K.D. Genealogy, expression, and cellular function of transforming growth factor-beta. Pharmacol. Ther. 98 (2003) 257-265
    • (2003) Pharmacol. Ther. , vol.98 , pp. 257-265
    • Govinden, R.1    Bhoola, K.D.2
  • 5
    • 0037013930 scopus 로고    scopus 로고
    • Mechanism of transforming growth factor beta-induced inhibition of T helper type 1 differentiation
    • Gorelik L., Constant S., and Flavell R.A. Mechanism of transforming growth factor beta-induced inhibition of T helper type 1 differentiation. J. Exp. Med. 195 (2002) 1499-1505
    • (2002) J. Exp. Med. , vol.195 , pp. 1499-1505
    • Gorelik, L.1    Constant, S.2    Flavell, R.A.3
  • 6
    • 0034121583 scopus 로고    scopus 로고
    • When engineered to produce latent TGF-beta1, antigen specific T cells down regulate Th1 cell-mediated autoimmune and Th2 cell-mediated allergic inflammatory processes
    • Thorbecke G.J., Umetsu D.T., deKruyff R.H., Hansen G., Chen L.Z., and Hochwald G.M. When engineered to produce latent TGF-beta1, antigen specific T cells down regulate Th1 cell-mediated autoimmune and Th2 cell-mediated allergic inflammatory processes. Cytokine Growth Factor Rev. 11 (2000) 89-96
    • (2000) Cytokine Growth Factor Rev. , vol.11 , pp. 89-96
    • Thorbecke, G.J.1    Umetsu, D.T.2    deKruyff, R.H.3    Hansen, G.4    Chen, L.Z.5    Hochwald, G.M.6
  • 7
    • 0026006736 scopus 로고
    • Successful treatment of experimental allergic encephalomyelitis with transforming growth factor-beta 1
    • Johns L.D., Flanders K.C., Ranges G.E., and Sriram S. Successful treatment of experimental allergic encephalomyelitis with transforming growth factor-beta 1. J. Immunol. 147 (1991) 1792-1796
    • (1991) J. Immunol. , vol.147 , pp. 1792-1796
    • Johns, L.D.1    Flanders, K.C.2    Ranges, G.E.3    Sriram, S.4
  • 8
    • 0033543127 scopus 로고    scopus 로고
    • Prevention of experimental allergic encephalomyelitis by intramuscular gene transfer with cytokine-encoding plasmid vectors
    • Piccirillo C.A., and Prud'homme G.J. Prevention of experimental allergic encephalomyelitis by intramuscular gene transfer with cytokine-encoding plasmid vectors. Hum. Gene Ther. 10 (1999) 1915-1922
    • (1999) Hum. Gene Ther. , vol.10 , pp. 1915-1922
    • Piccirillo, C.A.1    Prud'homme, G.J.2
  • 9
    • 0033953109 scopus 로고    scopus 로고
    • The inhibitory effects of transforming growth factor-beta-1 (TGF-beta1) in autoimmune diseases
    • Prud'homme G.J., and Piccirillo C.A. The inhibitory effects of transforming growth factor-beta-1 (TGF-beta1) in autoimmune diseases. J. Autoimmun. 14 (2000) 23-42
    • (2000) J. Autoimmun. , vol.14 , pp. 23-42
    • Prud'homme, G.J.1    Piccirillo, C.A.2
  • 10
    • 0025892475 scopus 로고
    • Prevention and treatment of chronic relapsing experimental allergic encephalomyelitis by transforming growth factor-beta 1
    • Racke M.K., Dhib-Jalbut S., Cannella B., Albert P.S., Raine C.S., and McFarlin D.E. Prevention and treatment of chronic relapsing experimental allergic encephalomyelitis by transforming growth factor-beta 1. J. Immunol. 146 (1991) 3012-3017
    • (1991) J. Immunol. , vol.146 , pp. 3012-3017
    • Racke, M.K.1    Dhib-Jalbut, S.2    Cannella, B.3    Albert, P.S.4    Raine, C.S.5    McFarlin, D.E.6
  • 11
    • 0027313082 scopus 로고
    • Studies on the mechanisms by which transforming growth factor-beta (TGF-β) protects against allergic encephalomyelitis. Antagonism between TGF-β and tumor necrosis factor
    • Santambrogio L., Hochwald G.M., Saxena B., Leu C.H., Martz J.E., Carlino J.A., Ruddle N.H., Palladino M.A., Gold L.I., and Thorbecke G.J. Studies on the mechanisms by which transforming growth factor-beta (TGF-β) protects against allergic encephalomyelitis. Antagonism between TGF-β and tumor necrosis factor. J. Immunol. 151 (1993) 1116-1127
    • (1993) J. Immunol. , vol.151 , pp. 1116-1127
    • Santambrogio, L.1    Hochwald, G.M.2    Saxena, B.3    Leu, C.H.4    Martz, J.E.5    Carlino, J.A.6    Ruddle, N.H.7    Palladino, M.A.8    Gold, L.I.9    Thorbecke, G.J.10
  • 12
    • 0141994811 scopus 로고    scopus 로고
    • Transforming growth factor-beta 1-mediated neuroprotection against excitotoxic injury in vivo
    • Boche D., Cunningham C., Gauldie J., and Perry V.H. Transforming growth factor-beta 1-mediated neuroprotection against excitotoxic injury in vivo. J. Cereb. Blood Flow Metab. 23 (2003) 1174-1182
    • (2003) J. Cereb. Blood Flow Metab. , vol.23 , pp. 1174-1182
    • Boche, D.1    Cunningham, C.2    Gauldie, J.3    Perry, V.H.4
  • 13
    • 0037095746 scopus 로고    scopus 로고
    • Transforming growth factor-beta 1 increases bad phosphorylation and protects neurons against damage
    • Zhu Y., Yang G.Y., Ahlemeyer B., Pang L., Che X.M., Culmsee C., Klumpp S., and Krieglstein J. Transforming growth factor-beta 1 increases bad phosphorylation and protects neurons against damage. J. Neurosci. 22 (2002) 3898-3909
    • (2002) J. Neurosci. , vol.22 , pp. 3898-3909
    • Zhu, Y.1    Yang, G.Y.2    Ahlemeyer, B.3    Pang, L.4    Che, X.M.5    Culmsee, C.6    Klumpp, S.7    Krieglstein, J.8
  • 14
    • 0345412011 scopus 로고    scopus 로고
    • FGF-2 and PDGF-AA in a myelination of CNS aggregate cultures enriched with macrophages
    • Diemel L.T., Jackson S.J., Cuzner M.L., and TGF-beta1 R.f. FGF-2 and PDGF-AA in a myelination of CNS aggregate cultures enriched with macrophages. J. Neurosci. Res. 74 (2003) 858-867
    • (2003) J. Neurosci. Res. , vol.74 , pp. 858-867
    • Diemel, L.T.1    Jackson, S.J.2    Cuzner, M.L.3    TGF-beta1, R.f.4
  • 17
    • 4944246703 scopus 로고    scopus 로고
    • Treatment of experimental autoimmune encephalomyelitis with a neurotropic alphavirus vector expressing tissue inhibitor of metalloproteinase-2
    • Nygårdas P.T., Grönberg S.A., Heikkilä J., Joronen K., Sorsa T., and Hinkkanen A.E. Treatment of experimental autoimmune encephalomyelitis with a neurotropic alphavirus vector expressing tissue inhibitor of metalloproteinase-2. Scand. J. Immunol. 60 (2004) 372-381
    • (2004) Scand. J. Immunol. , vol.60 , pp. 372-381
    • Nygårdas, P.T.1    Grönberg, S.A.2    Heikkilä, J.3    Joronen, K.4    Sorsa, T.5    Hinkkanen, A.E.6
  • 20
    • 0024312217 scopus 로고
    • Site-directed mutagenesis of cysteine residues in the pro region of the transforming growth factor beta 1 precursor. Expression and characterization of mutant proteins
    • Brunner A.M., Marquardt H., Malacko A.R., Lioubin M.N., and Purchio A.F. Site-directed mutagenesis of cysteine residues in the pro region of the transforming growth factor beta 1 precursor. Expression and characterization of mutant proteins. J. Biol. Chem. 264 (1989) 13660-13664
    • (1989) J. Biol. Chem. , vol.264 , pp. 13660-13664
    • Brunner, A.M.1    Marquardt, H.2    Malacko, A.R.3    Lioubin, M.N.4    Purchio, A.F.5
  • 22
    • 0346025622 scopus 로고    scopus 로고
    • Effect of intranasal administration of Semliki Forest virus recombinant particles expressing reporter and cytokine genes on the progression of experimental autoimmune encephalomyelitis
    • Jerusalmi A., Morris-Downes M.M., Sheahan B.J., and Atkins G.J. Effect of intranasal administration of Semliki Forest virus recombinant particles expressing reporter and cytokine genes on the progression of experimental autoimmune encephalomyelitis. Mol. Ther. 8 (2003) 886-894
    • (2003) Mol. Ther. , vol.8 , pp. 886-894
    • Jerusalmi, A.1    Morris-Downes, M.M.2    Sheahan, B.J.3    Atkins, G.J.4
  • 23
    • 32944474703 scopus 로고    scopus 로고
    • CNS gene therapy applications of the Semliki Forest virus 1 vector are limited by neurotoxicity
    • Graham A., Walker R., Baird P., Hahn C.N., and Fazakerley J.K. CNS gene therapy applications of the Semliki Forest virus 1 vector are limited by neurotoxicity. Mol. Ther. 13 (2006) 631-635
    • (2006) Mol. Ther. , vol.13 , pp. 631-635
    • Graham, A.1    Walker, R.2    Baird, P.3    Hahn, C.N.4    Fazakerley, J.K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.