Structure and bioactivities of a galactose rich extracellular polysaccharide from submergedly cultured Ganoderma lucidum

Carbohydrate Polymers

Volumn 68, Issue 2, 2007, Pages 323-328

  Li, Yan Qun ^a   Fang, Lu ^b   Zhang, Ke Chang ^c  

^a SOUTH CHINA NORMAL UNIVERSITY   (China)

^b Jiangxi Institute of Safety Science and Technology   (China)

^c JIANGNAN UNIVERSITY   (China)

Author keywords

Ganoderma lucidum; Hepatoprotection; Immunoregulation; Polysaccharide; Structure

Indexed keywords

ANTIBODIES; BLOOD; CONCENTRATION (PROCESS); GLUCOSE; IMMUNOLOGY; INFRARED SPECTROSCOPY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; TISSUE;

GALACTOSE; HEPATOPROTECTIVE ACTIVITY; IMMUNOREGULATION; MOLAR RATIOS;

POLYSACCHARIDES;

BASIDIOMYCOTA; GANODERMA LUCIDUM; MUS;

EID: 33847257274     PISSN: 01448617     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.carbpol.2006.12.001     Document Type: Article

References (20)

1. Back S.J., Jung W.T., Kim D.Y., and Cho K.D. G009: Hepatoprotectant, immunostimulant. Drugs Future 24 (1999) 1068-1071
2. Bao X.F., Liu C.P., Fang J.N., and Li X.Y. Structural and immunological studies of a major polysaccharide from spores of Ganoderma lucidum (Fr.) Karst. Carbohydrate Research 332 (2001) 67-74
3. Bao X.F., Wang X.S., Dong Q., Fang J.N., and Li X.Y. Structural features of immunologically active polysaccharides from Ganoderma lucidum. Phytochemistry 59 (2002) 175-181
4. Berovič M., Jožca H., Zore I., Wraber Br., Hodžar D., Boh B., et al. Submerged cultivation of Ganoderma lucidum biomass and immunostimulatory effects of fungal polysaccharides. Journal of Biotechnology 103 (2003) 77-86
5. Chen H.S., Tsai Y.F., Lin S., Lin C.C., Khoo K.H., Lin C.H., et al. Studies on the immuno-modulating and anti-tumor activities of Ganoderma lucidum (Reishi) polysaccharides. Bioorganic & Medicinal Chemistry 12 (2004) 5595-5601
6. Ciucanu I., and Kerek F. A simple and rapid method for permethylation of carbohydrates. Carbohydrate Research 131 (1984) 209-217
7. Gerwig G.J., Kamerling J.P., and Vliegenthart J.F.G. Determination of the d and l configuration of neutral monosaccharides by high-resolution capillary G.L.C. Carbohydrate Research 62 (1978) 349-357
8. Heek K., Reimann J., Kabelitz D., Hardt C., and Wagner H. A rapid colorimetric assay for the determination of IL-2-producing helper T cells frequencies. Journal of Immunological Methods 77 (1985) 237-246
9. Kim Y.S., Eo S.K., Oh K.W., Lee Ch.k., and Han S.S. Antiherpetic activities of acidic protein bound polysaccharide isolated from Ganoderma lucidum alone and in combinations with interferons. Journal of Ethnopharmacology 72 (2000) 451-458
10. Li T.L., Wu C.X., and Zhang Y.X. An improved GC analysis method of alditol acetates derivatives. Chinese Journal of Analytical Chemistry 10 5 (1982) 272-275
11. Miyazaki T., and Nishijima M. Studies on fungal polysaccharides XXVII. Structural examination of a water-soluble, antitumor polysaccharide of Ganoderma lucidum. Chemical and Pharmaceutical Bulletin 29 (1981) 3611-3616
12. Nagai H., Yakuo I., and Yamada H. Liver injury model in mice for immunopharmacological study. Japan Journal of Pharmacology 46 (1988) 247
13. Sahar E.M., Meselhy M.R., Nakamura N., Tezuka Y., Hattori M., Kakiuchi N., et al. Anti-HIV-1 and anti-HIV-1-protease substances from Ganoderma lucidum. Phytochemistry 49 (1998) 1651-1657
14. Sweet D.P., Shapiro R.H., and Albersheim P. Quantitative analysis by various GLC response-factor theories for partially methylated and partially ethylated alditol acetates. Carbohydrate Research. 40 (1975) 217-225
15. Vento S. T-lymphocytes sensitization to hepatocyte antigens in autoimmune chronic active hepatitis. Gastroenterology 91 4 (1986) 810-817
16. Wang S.Y., Hsu H.H., Tzeng C.H., Lee S.S., Shiao M.S., and Ho C.K. The antitumor effect of Ganoderma lucidum is mediated by cytokines released from activated macrophages and T lymphocytes. International Journal of Cancer 70 (1997) 699-705
17. Wang Y.Y., Khoo K.H., Chen S.T., Lin C.C., Wonga C.H., and Lina C.H. Studies on the immuno-modulating and antitumor activities of Ganoderma lucidum (Reishi) polysaccharides: functional and proteomic analyses of a fucose-containing glycoprotein fraction responsible for the activities. Bioorganic & Medicinal Chemistry 10 (2002) 1057-1062
18. Xiang D.B., and Li X.Y. Antitumor activity and immuno-potentiating actions of achyranthes bidentata polysaccharides. Acta Pharmacologica Sinica 14 (1993) 556-561
19. Zhou D.H., Shen Y.S., and Zhao M.R. The application of MTT colorimetric assay to measure the proliferation of lymphocytes and the activity of rat/mouse IL-2. Chinese Journal of Immunology 2 (1986) 39-46
20. Zhang J.S., Tang Q.J., Martin Z.K., Werner R., and Fan H. Activation of B lymphocytes by GLIS, a bioactive proteoglycan from Ganoderma lucidum. Life Sciences 71 (2002) 623-638