Antiherpetic activities of acidic protein bound polysacchride isolated from Ganoderma lucidum alone and in combinations with interferons

Journal of Ethnopharmacology

Volumn 72, Issue 3, 2000, Pages 451-458

  Kim, Young So ^a   Eo, Seong Kug ^a   Oh, Ki Wan ^a   Lee, Chong Kil ^a   Han, Seong Sun ^a  

^a Chungbuk National University   (South Korea)

Author keywords

Antiherpetic activity; Combination index (CI); Ganoderma lucidum; Herpes simplex viruses; Plaque reduction assay

Indexed keywords

ACID PROTEIN; ALPHA INTERFERON; GAMMA INTERFERON; INTERFERON; POLYSACCHARIDE;

ANTIVIRAL ACTIVITY; ARTICLE; CYTOTOXICITY; DRUG EFFECT; DRUG ISOLATION; HERPES; PROTEIN BINDING; STRAIN DIFFERENCE; TISSUE CULTURE; VIRUS CULTURE;

ANIMAL; APHYLLOPHORALES; CERCOPITHECUS AETHIOPS; HERPESVIRUS 1, HUMAN; HERPESVIRUS 2, HUMAN; HYDROGEN-ION CONCENTRATION; MICROBIAL SENSITIVITY TESTS; POLYSACCHARIDES; PROTEINS; SUPPORT, NON-U.S. GOV'T; VERO CELLS;

GANODERMA LUCIDUM;

EID: 0033795973     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-8741(00)00263-4     Document Type: Article

References (18)

1. Eo, S-K., Kim, Y-S., Lee, C-K., Han, S-S., 1999. Antiherpetic activities of various protein bound polysaccharides isolated from Ganoderma lucidum. Journal of Ethnopharmacology 68, 175-181.
2. Coen D.M. The implications of resistance to antiviral agents for herpesvirus drug targets and drug therapy. Antiviral Research. 15:1991;287-300.
3. Hikino H., Konno C., Mirin Y., Hayashi T. Isolation and hypoglycemic activity of ganoderans A and B, glycans of Ganoderma lucidum fruit bodies. Planta Medica. 51:1985;339-340.
4. Hook E.W. III, Cannon R.O., Nahmias A.J. Herpes simplex virus infection as a risk factor for human immunodeficiency virus infection in heterosexuals. Journal of Infectious Diseases. 165:1992;251-255.
5. Kim B.K., Chung H.S., Chung K.S., Yang M.S. Studies on the antineoplastic components of Korean basidiomycetes. Korean Journal of Mycology. 8:1980;107-113.
6. Kim M.J., Kim H.W., Lee Y.S., Shim M.J., Choi E.C., Kim B.K. Studies on safety of Ganoderma lucidum. Korean Journal of Mycology. 14:(1):1986;49-59.
7. Kim S.S., Kim Y.S. Korean Mushrooms. 1990;298-299 Yupoong, Seoul.
8. Lapucci A., Macchia M., Parkin A. Antiherpes virus agents: a review. IL Farmaco. 48:(7):1993;871-895.
9. Miyazaki T., Nishijima M. Studies on fungal polysaccharides. XXVII. Structural examination of a water-soluble, antitumor polysaccharide of Ganoderma lucidum. Chemical and Pharmaceutical Bulletin. 29:1981;3611-3616.
10. Nishitoba T., Sato H., Sakamura S. New terpenoids from Ganoderma lucidum and their bitterness. Agricural Biology and Chemistry. 49:1985;1547-1549.
11. 30 terpenoids from the fungus Ganoderma lucidum (Reishi). Agricural Biology and Chemistry. 49:1985;1793-1798.
12. Park J.H., Kim H.W., Kim Y.C., Choi E.C., Kim B.K. Studies on antihypertensive components of Ganoderma lucidum in Korea. Korean Journal of Food Hygiene. 2:1987;57-65.
13. Schinazi R.F., Chou T.-C., Scott R.T., Yao X., Nahmias A.J. Delayed treatment with combination of antiviral drugs in mice infected with herpes simplex virus and application of the median effect method of analysis. Antimicrobial Agents and Chemotherapy. 30:(3):1986;491-498.
14. Scubiero D.A., Shoemaker R.H., Paull K.D., Monks A., Tierney S., Nofziger T.H., Currens M.J., Seniff D., Boyd M.R. Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines. Cancer Research. 48:1988;4827-4833.
15. Shannon W.M. Mechanism of action and pharmacology: chemical agents. Galasso G.J., Merigan T.C., Buchanon R.A. Antiviral Agents and Viral Diseases of Man. 1984;55-121 Raven Press, New York.
16. Shigeta S., Mori S., Baba M., Ito M., Honzumi K., Nakamara K., Oshitani H., Numazaki Y., Matsuda A., Obara T., Shuto S., De Clercq E. Antiviral activities of ribavirin, 5-ethynyl-1-β-D-ribofuranosylimidazole-4-carboxamide, and 6′-(R)-6′-C-methylneplanocin A against several ortho- and paramyxoviruses. Antimicrobial Agents and Chemotherapy. 36:(2):1992;435-439.
17. Tachedijian G., Tyseen D., Jardine D., Lorcarnini S., Birch C. Synergistic inhibition of human immunodeficiency virus type I in vitro by interferon alpha and coumermycin A1. Antiviral Chemistry and Chemotherapy. 3:(3):1991;183-188.
18. Witvrouw M., Desmyter J., De Clercq E. Antiviral Chemistry and Chemotherapy. 5:1994;345-359.