Disruption of iron homeostasis increases phosphine toxicity in caenorhabditis elegans

Toxicological Sciences

Volumn 96, Issue 1, 2007, Pages 194-201

  Cha'on, Ubon ^a,d   Valmas, Nicholas ^a   Collins, Patrick J ^b   Reilly, Paul E B ^a   Hammock, Bruce D ^c   Ebert, Paul R ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b DEPARTMENT OF AGRICULTURE AND FISHERIES   (Australia)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d KHON KAEN UNIVERSITY   (Thailand)

Author keywords

C. elegans; Ferritin; Iron overload; Longevity; Oxidative stress; Phosphine

Indexed keywords

FERRIC ION; FERRITIN; FERROUS ION; PHOSPHINE;

ARTICLE; CAENORHABDITIS ELEGANS; CELL DAMAGE; CELL DEATH; CONTROLLED STUDY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE LOCATION; GENETIC CODE; GENETIC TRANSCRIPTION; IN SITU HYBRIDIZATION; IN VITRO STUDY; IRON BALANCE; IRON OVERLOAD; LIPID PEROXIDATION; NONHUMAN; PATHOPHYSIOLOGY; POLYMERASE CHAIN REACTION; QUANTITATIVE ANALYSIS; RNA INTERFERENCE; TOXICOKINETICS; TOXIN ANALYSIS;

ANIMALS; CAENORHABDITIS ELEGANS; DOSE-RESPONSE RELATIONSHIP, DRUG; FERRIC COMPOUNDS; FERRITINS; FERROUS COMPOUNDS; HELMINTH PROTEINS; HOMEOSTASIS; INSECTICIDES; INTESTINES; IRON; LIPID PEROXIDATION; OXIDATION-REDUCTION; PHOSPHINES; QUATERNARY AMMONIUM COMPOUNDS; RNA INTERFERENCE; RNA, MESSENGER; TIME FACTORS; UP-REGULATION;

CAENORHABDITIS ELEGANS; EQUIDAE;

EID: 33847253037     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfl187     Document Type: Article

References (35)

1. Ahmad, S., Kitchin, K. T.,and Cullen,W. R. (2000). Arsenic species that cause release of iron from ferritin and generation of activated oxygen. Arch. Biochem. Biophys. 382, 195-202.
2. Bartfay, W. J., Butany, J., Lehotay, D. C., Sole, M. J., Hou, D., Bartfay, E., and Liu, P. P. (1999). A biochemical, histochemical, and electron microscopic study on the effects of iron-loading on the hearts of mice. Cardiovasc. Pathol. 8, 305-314.
3. Bolter, C. J., and Chefurka,W. (1990). Extramitochondrial release of hydrogen-peroxide from insect and mouse-liver mitochondria using the respiratory inhibitors phosphine, myxothiazol, and antimycin and spectral-analysis of inhibited cytochromes. Arch. Biochem. Biophys. 278, 65-72.
4. Bond, E. J., Robinson, J. R., and Buckland, C. T. (1969). The toxic action of phosphine: Absorption and symptoms of poisoning in insects. J. Stored Prod. Res. 5, 289-298.
5. Brown, K. E., Kinter, M. T., Oberley, T. D., Freeman, M. L., Frierson, H. F., Ridnour, L. A., Tao, Y., Oberley, L. W., and Spitz, D. R. (1998). Enhanced gamma-glutamyl transpeptidase expression and selective loss of CuZn superoxide, dismutase in hepatic iron overload. Free Radic. Biol. Med. 24, 545-555.
6. Chaudhry, M. Q. (1997). A review of the mechanisms involved in the action of phosphine as an insecticide and phosphine resistance in stored-product insects. Pestic. Sci. 49, 213-228.
7. Chaudhry, M. Q., Bell, H. A., Savvidou, N., and MacNicoll, A. D. (2004). Effect of low temperatures on the rate of respiration and uptake of phosphine in different life stages of the cigarette beetle Lasioderma serricorne (F.). J. Stored Prod. Res. 40, 125-134.
8. Chaudhry, M. Q., and Price, N. R. (1992). Comparison of the oxidant damage induced by phosphine and the uptake and tracheal exchange of P-32 radiolabelled phosphine in the susceptible and resistant strains of Rhyzopertha-Dominica (F) (Coleoptera, Bostrychidae). Pestic. Biochem. Physiol. 42, 167-179.
9. Cheeseman, K. H. (1993). Mechanisms and effects of lipid-peroxidation. Mol. Aspects Med. 14, 191-197.
10. Cheng, Q., Valmas, N., Reailly, P. E. B., Collins, P. J., Kopittke, R., and Ebert, P. R. (2003). Caenorhabditis elegans mutants resistant to phosphine toxicity show increased longevity and cross-resistance to the synergistic action of oxygen. Toxicol. Sci. 73, 60-65.
11. Fields, P.G., and White,N.D.G. (2002). Alternatives to methyl bromide treatments for stored-product and quarantine insects. Annu. Rev. Entomol. 47, 331-359.
12. Gourley, B. L., Parker, S. B., Jones, B. J., Zumbrennen, K. B., and Leibold, E. A. (2003). Cytosolic aconitase and ferritin are regulated by iron in Caenorhabditis elegans. J. Biol. Chem. 278, 3227-3234.
13. Harrison, P. M., and Arosio, P. (1996). Ferritins: Molecular properties, iron storage function and cellular regulation. Biochim. Biophys. Acta Bioenerg. 1275, 161-203.
14. Ho, K. J., Liu, T. K., Huang, T. S., and Lu, F. J. (2003). Humic acid mediates iron release from ferritin and promotes lipid peroxidation in vitro: A possible mechanism for humic acid-induced cytotoxicity. Arch. Toxicol. 77, 100-109.
15. Hsu, C. H., Chi, B. C., and Casida, J. E. (2002a). Melatonin reduces phosphine-induced lipid and DNA oxidation in vitro and in vivo in rat brain. J. Pineal Res. 32, 53-58.
16. Hsu, C. H., Chi, B. C., Liu, M. Y., Li, J. H., Chen, C. J., and Chen, R. Y. (2002b). Phosphine-induced oxidative damage in rats: Role of glutathione. Toxicology 179, 1-8.
17. Hsu, C. H., Han, B. C., Liu, M. Y., Yeh, C. Y., and Casida, J. E. (2000). Phosphine-induced oxidative damage in rats: Attenuation by melatonin. Free Radic. Biol. Med. 28, 636-642.
18. Hsu, C. H., Quistad, G. B., and Casida, J. E. (1998). Phosphine-induced oxidative stress in Hepa 1c1c7 cells. Toxicol. Sci. 46, 204-210.
19. Jagetia, G. C., Reddy, T. K., Venkatesha, V. A., and Kedlaya, R. (2004). Influence of naringin on ferric iron induced oxidative damage in vitro. Clin. Chim. Acta 347, 189-197.
20. Kamath, R. S., Martinez-Campos, M., Zipperlen, P., Fraser, A. G., and Ahringer, J. (2000). Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in Caenorhabditis elegans. Genome Biol. 2, research0002.1-research0002.10.
21. Kashi, K. P. (1981). Response of 5 species of stored-product insects to phosphine in oxygen-deficient atmospheres. Pestic. Sci. 12, 111-115.
22. Kim, Y. I., Cho, J. H., Yoo, O. J., and Ahnn, J. (2004). Transcriptional regulation and life-span modulation of cytosolic aconitase and ferritin genes in C-elegans. J. Mol. Biol. 342, 421-433.
23. Loehr, T. M. (1989). Iron Carriers and Iron Proteins, pp. 216-225. Weinheim, New York.
24. Mihara, M., and Uchiyama, M. (1978). Determination of malonaldehyde precursor in tissues by thiobarbituric acid test. Anal. Biochem. 86, 271-278.
25. Minotti, G., and Aust, S. D. (1987). The role of iron in the initiation of lipid-peroxidation. Chem. Phys. Lipids 44, 191-208.
26. Nakakita, H. (1976). The inhibitory site of phosphine. Jpn. J. Appl. Entomol. Zool. 1, 235-238.
27. Price, N. R. (1980). Some aspects of the inhibition of cytochrome-c oxidase by phosphine in susceptible and resistant strains of Rhyzopertha-Dominica. Insect Biochem. 10, 147-150.
28. Qian, S.Y., andBuettner, G. R. (1999). Iron and dioxygen chemistry is an important route to initiation of biological free radical oxidations: An electron paramagnetic resonance spin trapping study. Free Radic. Biol. Med. 26, 1447-1456.
29. Quistad, G. B., Sparks, S. E., and Casida, J. E. (2000). Chemical model for phosphine-induced lipid peroxidation. Pest Manag. Sci. 56, 779-783.
30. Reif, D. W. (1992). Ferritin as a source of iron for oxidative damage. Free Radic. Biol. Med. 12, 417-427.
31. Seydoux, G., and Fire, A. (1995). Whole-mount in situ hybridization for the detection of RNA in Caenorhabditis elegans embryos. Methods Cell Biol. 48, 323-337.
32. Sirivech, S., Freiden, E., and Osaki, S. (1974). The release of iron from horse spleen ferritin by reduced flavins. Biochem. J. 143, 311-315.
33. Stookey, L. L. (1970). Ferrozine-A new spectrophotometric reagent for iron. Anal. Chem. 42, 779-781.
34. Thomas, C. E., and Aust, S. D. (1986). Reductive release of iron from ferritin by cation free-radicals of paraquat and other bipyridyls. J. Biol. Chem. 261, 3064-3070.
35. Wilkinson, J., Pietsch, E. C., Torti, S. V., and Torti, F. M. (2003). Ferritin regulation by oxidants and chemopreventive xenobiotics. Adv. Enzyme Regul. 43, 135-151.