Melatonin reduces phosphine-induced lipid and DNA oxidation in vitro and in vivo in rat brain

Journal of Pineal Research

Volumn 32, Issue 1, 2002, Pages 53-58

  Hsu, Ching Hung ^a   Chi, Bei Ching ^a   Casida, John E ^b  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Brain; Deoxyribonucleic acid; Free radical; Glutathione; Glutathione peroxidase; Lipid; Melatonin; Oxidation; Phosphine; Superoxide dismutase

Indexed keywords

ALKENE DERIVATIVE; GLUTATHIONE PEROXIDASE; GUANOSINE DERIVATIVE; MELATONIN; PHOSPHINE; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; CONTROLLED STUDY; FRONTAL CORTEX; LIPID OXIDATION; LIVER; LUNG; MALE; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; RAT; TISSUE HOMOGENATE;

ANIMALS; ANTIOXIDANTS; BRAIN; DEOXYGUANOSINE; DNA; DNA DAMAGE; GLUTATHIONE PEROXIDASE; INSECTICIDES; LIPID PEROXIDATION; MALE; MALONDIALDEHYDE; MELATONIN; PHOSPHINES; RATS; RATS, WISTAR; SUPEROXIDE DISMUTASE;

EID: 0036161353     PISSN: 07423098     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-079x.2002.10809.x     Document Type: Article

References (46)

1. Fatal aluminum phosphide poisoning
2. Neurohormone melatonin prevents cell damage: Effect on gene expression for antioxidant enzymes
3. Brain lipid peroxidation and antioxidant protectant mechanisms following acute cyanide intoxication
4. Melatonin stimulates brain glutathione peroxidase activity
5. Acute oral toxicity of aluminum phosphide in male albino rats (Wistar)
6. Nitrosation of melatonin by nitric oxide and peroxynitrite
7. The effect of phosphine treatment on superoxide dismutase, catalase, and peroxidase in the granary weevil, Sitophilus granarius
8. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
9. Melatonin protects neurons from singlet oxygen-induced apoptosis
10. A review of the mechanisms involved in the action of phosphine as an insecticide and phosphine resistance in stored-product insects
11. 32P-radiolabelled phosphine in the susceptible and resistant strains of Rhyzopertha dominica (F.) (Coleoptera: Bostrychidae)
12. Free radical scavengers and lipid peroxidation in acute aluminum phosphide poisoning
13. A critical evaluation of anti-peroxidant effect of intravenous magnesium in acute aluminium phosphide poisoning
14. Determination of aldehydic lipid peroxidation products: Malonaldehyde and 4-hydroxynonenal
15. Quantitative high-performance liquid chromatography analysis of DNA oxidized in vitro and in vivo
16. Preparation and properties of vesicles enclosed by fatty acid membranes
17. Solvents, fumigants and related compounds
18. Melatonin is a scavenger of peroxynitrite
19. Oxygen radicals and the nervous system
20. Rate constants for reaction of hydroxyl radicals with Tris, Tricine and HEPES buffers
21. Phosphine-induced oxidative stress in Hepa 1c1c7 cells
22. Phosphine-induced oxidative damage in rats: Attenuation by melatonin
23. Glutathione deficiency leads to mitochondrial damage in brain
24. Responses of glutathione system and antioxidant enzymes to exhaustive exercise and hydroperoxide
25. 3). Zur frage sog. Chronischen phosphorwasserstoffvergiftung
26. An experimental study on cardiotoxicity of aluminium phosphide
27. Potent protective effect of melatonin on in vivo paraquat-induced oxidative damage in rats
28. Nuclear localization of melatonin in different mammalian tissues: Immunocytochemical and radioimmunoassay evidence
29. Melatonin protects against age-related DNA damage in the brains of female senescence-accelerated mice
30. Spectrophotometric assay of superoxide dismutase activity based on the activated autoxidation of a tetracyclic catechol
31. Melatonin and its precursors scavenge nitric oxide
32. Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase
33. Role of lipid peroxidation and DNA damage in paraquat toxicity and the interaction of paraquat with ionizing radiation
34. Inhibitory effects of melatonin on ferric nitrilotriacetate-induced lipid peroxidation and oxidative DNA damage in the rat kidney
35. Chromium (III) -induced 8-hydroxydeoxyguanosine in DNA and its reduction by antioxidants: Comparative effects of melatonin, ascorbate, and vitamin E
36. Oxidative processes and antioxidative defense mechanisms in the aging brain
37. Oxidative damage in the central nervous system: Protection by melatonin
38. Pharmacological actions of melatonin in oxygen radical pathophysiology
39. Actions of melatonin in the reduction of oxidative stress: A review
40. Melatonin: A potent, endogenous hydroxyl radical scavenger
41. Melatonin directly scavenges hydrogen peroxide: A potentially new metabolic pathway of melatonin biotransformation
42. Phosphine
43. Scavenging of NO by melatonin
44. Melatonin protects against ischemia and reperfusion-induced oxidative lipid and DNA damage in fetal rat brain
45. Phosphine and selected metal phosphides
46. Preventive effect of melatonin against cyanide-induced seizures and lipid peroxidation in mice