Compensation of type I and type II cytokeratin pools in lung cancer

Lung Cancer

Volumn 55, Issue 3, 2007, Pages 295-302

  Kanaji, Nobuhiro ^a   Bandoh, Shuji ^a   Fujita, Jiro ^b   Ishii, Tomoya ^a   Ishida, Toshihiko ^a   Kubo, Akihito ^c  

^a KAGAWA UNIVERSITY   (Japan)

^b UNIVERSITY OF THE RYUKYUS   (Japan)

^c NATIONAL HOSPITAL ORGANIZATION KINKI CHUO CHEST MEDICAL CENTER   (Japan)

Author keywords

CK19; Compensation; Cytokeratin; Non small cell lung cancer (NSCLC); RNA interference

Indexed keywords

CYTOKERATIN; CYTOKERATIN 18; CYTOKERATIN 19; CYTOKERATIN 8; CYTOKERATIN TYPE 1; CYTOKERATIN TYPE 2; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DOWN REGULATION; EVALUATION; HUMAN; HUMAN CELL; LUNG CANCER; LUNG NON SMALL CELL CANCER; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN TARGETING; QUANTITATIVE ANALYSIS; RNA INTERFERENCE; UPREGULATION;

ADENOCARCINOMA; CARCINOMA, NON-SMALL-CELL LUNG; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; HUMANS; KERATIN-19; KERATINS, TYPE I; KERATINS, TYPE II; LUNG NEOPLASMS; MICROSCOPY, FLUORESCENCE; RNA, SMALL INTERFERING;

EID: 33847249064     PISSN: 01695002     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lungcan.2006.11.004     Document Type: Article

References (29)

1. Paramio J.M., and Jorcano J.L. Beyond structure: do intermediate filaments modulate cell signaling?. Bioessays 24 (2002) 836-844
2. Coulombe P.A., and Omary M.B. 'Hard' and 'soft' principles defining the structure, function and regulation of keratin intermediate filaments. Curr Opin Cell Biol 14 (2002) 110-122
3. Omary M.B., and Ku N.O. Intermediate filament proteins of the liver: emerging disease association and functions. Hepatology 25 (1997) 1043-1048
4. Omary M.B., Coulombe P.A., and McLean W.H. Intermediate filament proteins and their associated diseases. New Engl J Med 351 (2004) 2087-2100
5. Quinlan R.A., Schiller D.L., Hatzfeld M., Achtstatter T., Moll R., Jorcano J.L., et al. Patterns of expression and organization of cytokeratin intermediate filaments. Ann NY Acad Sci 455 (1985) 282-306
6. Baribault H., and Oshima R.G. Polarized and functional epithelia can form after the targeted inactivation of both mouse keratin 8 alleles. J Cell Biol 115 (1991) 1675-1684
7. Ku N.O., Michie S., Oshima R.G., and Omary M.B. Chronic hepatitis, hepatocyte fragility, and increased soluble phosphoglycokeratins in transgenic mice expressing a keratin 18 conserved arginine mutant. J Cell Biol 131 (1995) 1303-1314
8. Reichelt J., Bauer C., Porter R., Lane E., Herzog V., and Magin T. Out of balance: consequences of a partial keratin 10 knockout. J Cell Sci 110 (1997) 2175-2186
9. Lloyd C., Yu Q.C., Cheng J., Turksen K., Degenstein L., Hutton E., et al. The basal keratin network of stratified squamous epithelia: defining K15 function in the absence of K14. J Cell Biol 129 (1995) 1329-1344
10. Tamai Y., Ishikawa T., Bosl M.R., Mori M., Nozaki M., Baribault H., et al. Cytokeratins 8 and 19 in the mouse placental development. J Cell Biol 151 (2000) 563-572
11. Ueda Y., Fujita J., Bandoh S., Hojo S., Yamaji Y., Ohtsuki Y., et al. Expression of cytokeratin 19 mRNA in human lung cancer cell lines. Int J Cancer 81 (1999) 939-943
12. Paramio J.M., Segrelles C., Ruiz s., and Jorcano J.L. Inhibition of protein kinase B (PKB) and PKCzeta mediates keratin K10-induced cell cycle arrest. Mol Cell Biol 21 (2001) 7449-7459
13. Tojo Y., Bandoh S., Fujita J., Kubo A., Ishii T., Fukunaga Y., et al. Aberrant messenger RNA splicing of the cytokeratin 8 in lung cancer. Lung Cancer 42 (2003) 153-161
14. Sumida A., Kinoshita K., Fukuda T., Matsuda H., Yamamoto I., Inaba T., et al. Relationship between mRNA levels quantified by reverse transcription-competitive PCR and metabolic activity of CYP3A4 and CYP2E1 in human liver. Biochem Biophys Res Commun 262 (1999) 499-503
15. Fukunaga Y., Bandoh S., Fujita J., Yang Y., Ueda Y., Hojo S., et al. Expression of cytokeratin 8 in lung cancer cell lines and measurement of serum cytokeratin 8 in lung cancer patients. Lung Cancer 38 (2002) 31-38
16. Kim K.H., Marchuk D., and Fuchs E. Expression of unusually large keratins during terminal differentiation: balance of type I and type II keratins is not disrupted. J Cell Biol 99 (1984) 1872-1877
17. Chou C.F., Riopel C.L., Rott L.S., and Omary M.B. A significant soluble keratin fraction in 'simple' epithelial cells. J Cell Sci 105 (1993) 433-444
18. Godfroid E., Geuskens M., Dupressoir T., Parent I., and Szpirer C. Cytokeratins are exposed on the outer surface of established human mammary carcinoma cells. J Cell Sci 99 (1991) 595-607
19. Pujol J.L., Grenier J., Parrat E., Lehmann M., Lafontaine T., Quantin X., et al. Cytokeratins as serum markers in lung cancer: a comparison of CYFRA 21-1 and TPS. Am J Respir Crit Care Med 154 (1996) 725-733
20. Fujita J., Dohmoto K., Hojo S., Ueda Y., Bandoh S., Yang Y., et al. The point mutation in the promoter region and the single nucleotide polymorphism in exon 1 of the cytokeratin 19 gene in human lung cancer cell lines. Lung Cancer 34 (2001) 387-394
21. Grille S.J., Bellacosa A., Upson J., Klein-Szanto A.J., van Roy F., Lee-Kwon W., et al. The protein kinase Akt induces epithelial mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma lines. Cancer Res 63 (2003) 2172-2178
22. Pang Y.Y., Schermer A., Yu J., and Sun T.T. Suprabasal change and subsequent formation of disulfide-stabilized homo- and hetero-dimers of keratins during esophageal epithelial differentiation. J Cell Sci 104 (1993) 727-740
23. Steinert P.M. The two-chain coiled-coil molecule of native epidermal keratin intermediate filaments is a type I-type II heterodimer. J Biol Chem 265 (1990) 8766-8774
24. Schnabel J., Weber K., and Hatzfeld M. Protein-protein interactions between keratin polypeptides expressed in the yeast two-hybrid system. Biochim Biophys Acta 1403 (1998) 158-168
25. Reichelt J., Bussow H., Grund C., and Magin T.M. Formation of a normal epidermis supported by increased stability of keratins 5 and 14 in keratin 10 null mice. Mol Biol Cell 12 (2001) 1557-1568
26. Ando S., Kimura H., Iwai N., Yamamoto N., and Iida T. Positive reactions for both Cyfra21-1 and CA125 indicate worst prognosis in non-small cell lung cancer. Anticancer Res 23 (2003) 2869-2874
27. Chausovsky G., Luchansky M., Figer A., Shapira J., Gottfried M., Novis B., et al. Expression of cytokeratin 20 in the blood of patients with disseminated carcinoma of the pancreas, colon, stomach, and lung. Cancer 86 (1999) 2398-2405
28. Giudice G.J., and Fuchs E. The transfection of epidermal keratin genes into fibroblasts and simple epithelial cells. Cell 48 (1987) 453-463
29. Ku N.O., and Omary M.B. Keratins turn over by ubiquitination in a phosphorylation-modulated fashion. J Cell Biol 149 (2000) 547-552