UCN-01 (7-hydroxystaurosporine) induces apoptosis and G1 arrest of both primary and metastatic oral cancer cell lines in vitro

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology

Volumn 103, Issue 3, 2007, Pages 391-397

  Otsubo, Akira ^a   Bhawal, Ujjal Kumar ^b   Nomura, Yuji ^c   Mitani, Yoshitsugu ^c   Ozawa, Koichiro ^c   Kuniyasu, Hiroki ^d   Sugiyama, Masaru ^e  

^a NIHON UNIVERSITY   (Japan)

^b Research and Development   (Japan)

^c HIROSHIMA UNIVERSITY   (Japan)

^d NARA MEDICAL UNIVERSITY   (Japan)

^e School of Oral Health Science   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

7 HYDROXYSTAUROSPORINE; 7-HYDROXYSTAUROSPORINE; ANTINEOPLASTIC AGENT; CYCLIN DEPENDENT KINASE INHIBITOR 1A; DRUG DERIVATIVE; PROTEIN KINASE C; PROTEIN KINASE INHIBITOR; STAUROSPORINE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL CYCLE G1 PHASE; CELL PROLIFERATION; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; DRUG RESISTANCE; FLOW CYTOMETRY; HUMAN; METASTASIS; MOUTH TUMOR; PATHOLOGY; SQUAMOUS CELL CARCINOMA; TUMOR CELL LINE; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, NEOPLASM; FLOW CYTOMETRY; G1 PHASE; HUMANS; MOUTH NEOPLASMS; PROTEIN KINASE C; PROTEIN KINASE INHIBITORS; STAUROSPORINE;

EID: 33847203310     PISSN: 10792104     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tripleo.2005.11.022     Document Type: Article

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