Synthesis and evaluation of 4-O-alkylated 2-deoxy-2,3-didehydro-N-acetylneuraminic acid derivatives as inhibitors of human parainfluenza virus type-3 sialidase activity

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 6, 2007, Pages 1655-1658

  Tindal, David J ^a   Dyason, Jeffrey C ^a   Thomson, Robin J ^a   Suzuki, Takashi ^b   Ueyama, Hiroo ^b   Kuwahara, Yohta ^b   Maki, Naoyoshi ^b   Suzuki, Yasuo ^b   Von Itzstein, Mark ^a  

^a GRIFFITH UNIVERSITY   (Australia)

^b UNIVERSITY OF SHIZUOKA   (Japan)

Author keywords

Carbohydrates; Computational chemistry; Inhibition; Inhibitor design; Parainfluenza virus; Sialic acids; Sialidase

Indexed keywords

ANTIVIRUS AGENT; HN PROTEIN; N ACETYL 2,3 DIDEHYDRO 2 DEOXYNEURAMINIC ACID; SIALIDASE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CRYSTAL STRUCTURE; DRUG SCREENING; DRUG SYNTHESIS; ENZYME ACTIVITY; NEWCASTLE DISEASE PARAMYXOVIRUS; PARAINFLUENZA VIRUS 3;

CELL LINE; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; HUMANS; INDICATORS AND REAGENTS; N-ACETYLNEURAMINIC ACID; NEURAMINIDASE; PARAINFLUENZA VIRUS 3, HUMAN; SPECTROMETRY, FLUORESCENCE;

HUMAN PARAINFLUENZA VIRUS 3; NEWCASTLE DISEASE VIRUS; PARAINFLUENZA VIRUS;

EID: 33847183880     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.12.105     Document Type: Article

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