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Volumn 14, Issue 1, 2007, Pages 106-112

Hematologic adverse effects of clopidogrel

Author keywords

Acquired hemophilia; Autoimmune thrombocytopenia; Clopidogrel; Neutropenia; Plavix; Purpura; Thrombocytopenia

Indexed keywords

2 (2 CHLOROPHENYL) 2 (4,5,6,7 TETRAHYDROTHIENO[3,2 C]PYRIDIN 5 YL)ACETIC ACID; ACETYLSALICYLIC ACID; AZATHIOPRINE; CLOPIDOGREL; DRUG METABOLITE; IMMUNOGLOBULIN; MEPREDNISONE; PLACEBO; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; STEROID; TICLOPIDINE;

EID: 33847151775     PISSN: 10752765     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.mjt.0000212708.81034.22     Document Type: Review
Times cited : (34)

References (48)
  • 1
    • 18644372477 scopus 로고    scopus 로고
    • Structure and stereochemistry of the active metabolite of clopidogrel
    • Pereillo JM, Maftouh M, Andrieu A, et al. Structure and stereochemistry of the active metabolite of clopidogrel. Am Soc Pharmacol Exp Ther. 2002;11:1288-1295.
    • (2002) Am Soc Pharmacol Exp Ther , vol.11 , pp. 1288-1295
    • Pereillo, J.M.1    Maftouh, M.2    Andrieu, A.3
  • 2
    • 0032777493 scopus 로고    scopus 로고
    • Repeated-dose pharmacodynamics of clopidogrel in healthy subjects
    • Thebault JJ, Kieffer G, Lowe GD, et al. Repeated-dose pharmacodynamics of clopidogrel in healthy subjects. Seminol Thromb Hemostasis. 1999;25:9-14.
    • (1999) Seminol Thromb Hemostasis , vol.25 , pp. 9-14
    • Thebault, J.J.1    Kieffer, G.2    Lowe, G.D.3
  • 3
    • 0030590746 scopus 로고    scopus 로고
    • A randomized, blinded, trial of clopidogrel versus aspirin in patients at risk of ischemic events (CAPRIE)
    • CAPRIE Steering Committee
    • CAPRIE Steering Committee. A randomized, blinded, trial of clopidogrel versus aspirin in patients at risk of ischemic events (CAPRIE). Lancet. 1996;348:1329-1339.
    • (1996) Lancet , vol.348 , pp. 1329-1339
  • 4
    • 17744374250 scopus 로고    scopus 로고
    • The clopidogrel in unstable angina to prevent recurrent events (CURE) trial programme; rationale, design and baseline characteristics including a meta-analysis of the effects of thienopyridines in vascular disease
    • for CURE Study Investigators
    • Mehta SR, Yusuf S, for CURE Study Investigators. The clopidogrel in unstable angina to prevent recurrent events (CURE) trial programme; rationale, design and baseline characteristics including a meta-analysis of the effects of thienopyridines in vascular disease. Eur Heart J. 2000;21:2033-2041.
    • (2000) Eur Heart J , vol.21 , pp. 2033-2041
    • Mehta, S.R.1    Yusuf, S.2
  • 5
    • 3242770664 scopus 로고    scopus 로고
    • Aspirin and clopidogrel with clopidogrel alone after recent ischeamic stroke or transient ischaemic attack in high-risk patients (MATCH): Randomized, double-blind, placebo-controlled trial
    • Diener HC, Bogousslavsky J, Brass LM, et al. Aspirin and clopidogrel with clopidogrel alone after recent ischeamic stroke or transient ischaemic attack in high-risk patients (MATCH): randomized, double-blind, placebo-controlled trial. Lancet. 2004;364:331-337.
    • (2004) Lancet , vol.364 , pp. 331-337
    • Diener, H.C.1    Bogousslavsky, J.2    Brass, L.M.3
  • 6
    • 0037145863 scopus 로고    scopus 로고
    • Early and sustained dual oral antiplatelet therapy following percutaneous coronary intervention: A randomized controlled trial
    • Steinbul S, Berber P, Mann JT, et al. Early and sustained dual oral antiplatelet therapy following percutaneous coronary intervention: a randomized controlled trial. JAMA. 2002;288:2411-2420.
    • (2002) JAMA , vol.288 , pp. 2411-2420
    • Steinbul, S.1    Berber, P.2    Mann, J.T.3
  • 7
    • 20144373281 scopus 로고    scopus 로고
    • CLARITY-TIMI 28 investigators. Addition of clopidogrel to aspirin and fibrinolytic therapy for myocardial infarction with ST-segment elevation
    • Sabastine MS, Cannon CP, Gibson CM, et al. CLARITY-TIMI 28 investigators. Addition of clopidogrel to aspirin and fibrinolytic therapy for myocardial infarction with ST-segment elevation. N Engl J Med. 2005;352:1179-1189.
    • (2005) N Engl J Med , vol.352 , pp. 1179-1189
    • Sabastine, M.S.1    Cannon, C.P.2    Gibson, C.M.3
  • 8
    • 3242763532 scopus 로고    scopus 로고
    • Double-blind study of the safety of clopidogrel with and without a loading dose in combination with aspirin compared with ticlopidine in combination with aspirin after coronary stenting
    • Micheal EB, Rupprecht HJ, Urban P, et al. Double-blind study of the safety of clopidogrel with and without a loading dose in combination with aspirin compared with ticlopidine in combination with aspirin after coronary stenting. Circulation. 2000;102:624.
    • (2000) Circulation , vol.102 , pp. 624
    • Micheal, E.B.1    Rupprecht, H.J.2    Urban, P.3
  • 9
    • 0035825275 scopus 로고    scopus 로고
    • Febrile pancytopenia associated with Clopidogrel
    • Andres E, Perrin AE, Alt M, et al. Febrile pancytopenia associated with Clopidogrel. Arch Inter Med. 2001;161:125.
    • (2001) Arch Inter Med , vol.161 , pp. 125
    • Andres, E.1    Perrin, A.E.2    Alt, M.3
  • 10
    • 4143132020 scopus 로고    scopus 로고
    • Neutropenia due to clopidogrel in a patient with end-stage renal disease
    • Akcay A, Kanbay M, Agca E, et al. Neutropenia due to clopidogrel in a patient with end-stage renal disease. Ann Pharmacother. 2004;38:1538-1539.
    • (2004) Ann Pharmacother , vol.38 , pp. 1538-1539
    • Akcay, A.1    Kanbay, M.2    Agca, E.3
  • 11
    • 1542542072 scopus 로고    scopus 로고
    • Safety and efficacy evaluation of clopidogrel compared to ticlopidine after stent implantation: An updated metaanalysis
    • Casella G, Ottani F, Pavesi PC, et al. Safety and efficacy evaluation of clopidogrel compared to ticlopidine after stent implantation: an updated metaanalysis. Italian Heart J. 2003;4:677-684.
    • (2003) Italian Heart J , vol.4 , pp. 677-684
    • Casella, G.1    Ottani, F.2    Pavesi, P.C.3
  • 13
    • 15244340408 scopus 로고    scopus 로고
    • Treatment of acquired hemophilia by the Bonn-Malmö Protocol: Documentation of an in vivo immunomodulating concept
    • Zeitler H, Ulrich-Merzenich G, Hess L, et al. Treatment of acquired hemophilia by the Bonn-Malmö Protocol: documentation of an in vivo immunomodulating concept. Blood. 2005;105:2287-2293.
    • (2005) Blood , vol.105 , pp. 2287-2293
    • Zeitler, H.1    Ulrich-Merzenich, G.2    Hess, L.3
  • 14
    • 0019501541 scopus 로고
    • A survey of 215 non-hemophilic patients with inhibitors to factor eight
    • Green D, Lechner K. A survey of 215 non-hemophilic patients with inhibitors to factor eight. Thromb Hemostasis. 1981;45:200-203.
    • (1981) Thromb Hemostasis , vol.45 , pp. 200-203
    • Green, D.1    Lechner, K.2
  • 15
    • 4043084783 scopus 로고    scopus 로고
    • Acquired haemophilia A may be associated with clopidogrel
    • Haj M, Dasani H, Kundu S, et al. Acquired haemophilia A may be associated with clopidogrel. Br Med J. 2004;329:323.
    • (2004) Br Med J , vol.329 , pp. 323
    • Haj, M.1    Dasani, H.2    Kundu, S.3
  • 16
    • 33847093721 scopus 로고
    • Acquired hemophilia and its management
    • Morrison AE, Ludlum CA. Acquired hemophilia and its management. Br J Haematol. 1995;89:213-216.
    • (1995) Br J Haematol , vol.89 , pp. 213-216
    • Morrison, A.E.1    Ludlum, C.A.2
  • 17
    • 4043084783 scopus 로고    scopus 로고
    • Acquired hemophilia may be associatedwith clopidogrel
    • Haj M, Dasani H, Kundu S, et al. Acquired hemophilia may be associatedwith clopidogrel. Br Med J. 2004;329:323.
    • (2004) Br Med J , vol.329 , pp. 323
    • Haj, M.1    Dasani, H.2    Kundu, S.3
  • 18
    • 0037187949 scopus 로고    scopus 로고
    • Immune thrombocytopenic purpura
    • Cines DB, Blanchette VS. Immune thrombocytopenic purpura. N Engl J Med. 2002;346:995-1008.
    • (2002) N Engl J Med , vol.346 , pp. 995-1008
    • Cines, D.B.1    Blanchette, V.S.2
  • 19
    • 0034293123 scopus 로고    scopus 로고
    • Isolated profound thrombocytopenia associated with clopidogrel
    • Elmi F, Peacock T, Schiavone J. Isolated profound thrombocytopenia associated with clopidogrel. J Invasive Cardiol. 2000;12:532-535.
    • (2000) J Invasive Cardiol , vol.12 , pp. 532-535
    • Elmi, F.1    Peacock, T.2    Schiavone, J.3
  • 20
    • 9444251679 scopus 로고    scopus 로고
    • Clopidogrel associated severe Isolated Thrombocytopenia: A case report
    • Chen-Hung Su, Chin-Feng Tsai, Kwo-Chang Ueng, et al. Clopidogrel associated severe Isolated Thrombocytopenia: A case report. Acta Cardiol Sin. 2004;20:182-186.
    • (2004) Acta Cardiol Sin , vol.20 , pp. 182-186
    • Su, C.1    Tsai, C.2    Ueng, K.3
  • 22
    • 0034660472 scopus 로고    scopus 로고
    • Thrombotic thrombocytopenic purpura associated with clopidogrel
    • Bennet CI, Connors JM, Carwile JM, et al. Thrombotic thrombocytopenic purpura associated with clopidogrel. N Engl J Med. 2000;342:1773-1777.
    • (2000) N Engl J Med , vol.342 , pp. 1773-1777
    • Bennet, C.I.1    Connors, J.M.2    Carwile, J.M.3
  • 23
    • 84936619463 scopus 로고
    • Thrombotic thrombocytopenic purpura: Report of 16 cases and review of the literature
    • Amorosi E, Ultmann J. Thrombotic thrombocytopenic purpura: report of 16 cases and review of the literature. Medicine (Baltimore). 1966;45:139-159.
    • (1966) Medicine (Baltimore) , vol.45 , pp. 139-159
    • Amorosi, E.1    Ultmann, J.2
  • 24
    • 0038784315 scopus 로고    scopus 로고
    • Clopidogrel and thrombotic thrombocytopenic purpura: No clear cause for causality
    • Navneet SM, Alan EL. Clopidogrel and thrombotic thrombocytopenic purpura: no clear cause for causality. Cleveland Clin J Med. 2003;70:466-470.
    • (2003) Cleveland Clin J Med , vol.70 , pp. 466-470
    • Navneet, S.M.1    Alan, E.L.2
  • 25
    • 0030962025 scopus 로고    scopus 로고
    • Cancer- and drug-associated thrombotic thrombocytopenic purpura and hemolytic uremic syndrome
    • Gordon LI, Kwaan HC. Cancer- and drug-associated thrombotic thrombocytopenic purpura and hemolytic uremic syndrome. Semin Hematol. 1997;34:140-147.
    • (1997) Semin Hematol , vol.34 , pp. 140-147
    • Gordon, L.I.1    Kwaan, H.C.2
  • 26
    • 0032569840 scopus 로고    scopus 로고
    • Antibodies to von Willebrand factor-cleaving protease in acute thrombotic thrombocytopenic purpura
    • Tsai H-M, Lian EC-Y. Antibodies to von Willebrand factor-cleaving protease in acute thrombotic thrombocytopenic purpura. N Engl J Med. 1998;339:1585-1594.
    • (1998) N Engl J Med , vol.339 , pp. 1585-1594
    • Tsai, H.-M.1    Lian, E.C.-Y.2
  • 27
    • 0032569884 scopus 로고    scopus 로고
    • Von Willebrand factor-cleaving protease in thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome
    • Furlan M, Robles R, Galbusera M, et al. Von Willebrand factor-cleaving protease in thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome. N Engl J Med. 1998;339:1578-1584.
    • (1998) N Engl J Med , vol.339 , pp. 1578-1584
    • Furlan, M.1    Robles, R.2    Galbusera, M.3
  • 28
    • 0032569837 scopus 로고    scopus 로고
    • multimers and metalloprotease
    • Moake JL. Moschcowitz. multimers and metalloprotease. N Engl J Med. 1998;339:1629-1631.
    • (1998) N Engl J Med , vol.339 , pp. 1629-1631
    • Moschcowitz, M.J.L.1
  • 30
    • 0008426729 scopus 로고    scopus 로고
    • Thrombotic thrombocytopenic purpura occurring after exposure to clopidogrel
    • Abstract
    • Carwile JM, Laber DA, Soltero ER, et al. Thrombotic thrombocytopenic purpura occurring after exposure to clopidogrel. Blood. 1999;94:78b-78b. Abstract.
    • (1999) Blood , vol.94
    • Carwile, J.M.1    Laber, D.A.2    Soltero, E.R.3
  • 31
    • 0032055447 scopus 로고    scopus 로고
    • Thrombotic thrombocytopenic purpura associated with ticlopidine: A review of 60 cases
    • Bennet CL, Weinberg PD, Rozenberg-Ben-Dor K, et al. Thrombotic thrombocytopenic purpura associated with ticlopidine: a review of 60 cases. Ann Internal Med. 1998;128:541-544.
    • (1998) Ann Internal Med , vol.128 , pp. 541-544
    • Bennet, C.L.1    Weinberg, P.D.2    Rozenberg-Ben-Dor, K.3
  • 32
    • 0033518847 scopus 로고    scopus 로고
    • Incidence and clinical course of thrombotic thrombocytopenic purpura due to ticlopidine following coronary stenting
    • Steinhubl SR, Tan WA, Foody JM, et al. Incidence and clinical course of thrombotic thrombocytopenic purpura due to ticlopidine following coronary stenting. JAMA. 1998;281:806-810.
    • (1998) JAMA , vol.281 , pp. 806-810
    • Steinhubl, S.R.1    Tan, W.A.2    Foody, J.M.3
  • 33
    • 79960970597 scopus 로고    scopus 로고
    • Plasmapheresis improves survival in drug-induced thrombotic thrombocytopenic purpura: Systematic review of published case reports
    • Majhail NS, Lichtin AE. Plasmapheresis improves survival in drug-induced thrombotic thrombocytopenic purpura: systematic review of published case reports. Blood. 2001;98:60b.
    • (2001) Blood , vol.98
    • Majhail, N.S.1    Lichtin, A.E.2
  • 35
    • 0025077477 scopus 로고
    • The epidemiology and clinical aspects of the hemolytic uremic syndrome in Minnesota
    • Martin DL, MacDonald KL, White KE. The epidemiology and clinical aspects of the hemolytic uremic syndrome in Minnesota. N Engl J Med. 1990;323:1161-1167.
    • (1990) N Engl J Med , vol.323 , pp. 1161-1167
    • Martin, D.L.1    MacDonald, K.L.2    White, K.E.3
  • 36
    • 0034824687 scopus 로고    scopus 로고
    • Drug associated thrombotic thrombocytopenic purpura-hemolytic uremic syndrome
    • Medina PJ, Sipols JM, George JN. Drug associated thrombotic thrombocytopenic purpura-hemolytic uremic syndrome. Curr Opin Hematol. 2001;8:286-293.
    • (2001) Curr Opin Hematol , vol.8 , pp. 286-293
    • Medina, P.J.1    Sipols, J.M.2    George, J.N.3
  • 37
    • 0035014787 scopus 로고    scopus 로고
    • Andre AK. Aphaeresis for renal disease. Ther Aphaeresis Dialysis. 2001;5.2:134-141.
    • Andre AK. Aphaeresis for renal disease. Ther Aphaeresis Dialysis. 2001;5.2:134-141.
  • 38
    • 0037183855 scopus 로고    scopus 로고
    • TTP/HUS occurring in a simultaneous pancreas/kidney transplant recipient after clopidogrel treatment: Evidence of a nonimmunological etiology
    • Evens AM, Kwaan HC, Kaufman DB. TTP/HUS occurring in a simultaneous pancreas/kidney transplant recipient after clopidogrel treatment: evidence of a nonimmunological etiology. Transplantation. 2002;74:885-887.
    • (2002) Transplantation , vol.74 , pp. 885-887
    • Evens, A.M.1    Kwaan, H.C.2    Kaufman, D.B.3
  • 39
    • 20844459060 scopus 로고    scopus 로고
    • ACC/AHA 2004 guideline update for coronary artery bypass graft surgery: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Update the 1999 Guidelines for Coronary Artery Bypass Graft Surgery)
    • Eagle KA, Guyton RA, Davidoff R, et al. ACC/AHA 2004 guideline update for coronary artery bypass graft surgery: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Update the 1999 Guidelines for Coronary Artery Bypass Graft Surgery). Circulation. 2004;110:1168-1176.
    • (2004) Circulation , vol.110 , pp. 1168-1176
    • Eagle, K.A.1    Guyton, R.A.2    Davidoff, R.3
  • 40
    • 4444284981 scopus 로고    scopus 로고
    • Clopidogrel and bleeding in patients undergoing elective coronary artery bypass grafting
    • Chen L, Bracey AW, Radovancevic R, et al. Clopidogrel and bleeding in patients undergoing elective coronary artery bypass grafting. J Thorac Cardiovasc Surg. 2004;128:425-431.
    • (2004) J Thorac Cardiovasc Surg , vol.128 , pp. 425-431
    • Chen, L.1    Bracey, A.W.2    Radovancevic, R.3
  • 41
    • 19644373751 scopus 로고    scopus 로고
    • Does clopidogrel increase blood loss following coronary artery bypass surgery?
    • Chu MW, Wilson SR, Novick RJ, et al. Does clopidogrel increase blood loss following coronary artery bypass surgery? Ann Thorac Surg 2004;78:1536-1541.
    • (2004) Ann Thorac Surg , vol.78 , pp. 1536-1541
    • Chu, M.W.1    Wilson, S.R.2    Novick, R.J.3
  • 42
    • 0037125390 scopus 로고    scopus 로고
    • The effect of clopidogrel in combination with aspirin when given before coronary artery bypass grafting
    • Hongo RH, Ley J, Dick SE, et al. The effect of clopidogrel in combination with aspirin when given before coronary artery bypass grafting. J Am Coll Cardiol. 2002;40:231-237.
    • (2002) J Am Coll Cardiol , vol.40 , pp. 231-237
    • Hongo, R.H.1    Ley, J.2    Dick, S.E.3
  • 43
    • 0034070620 scopus 로고    scopus 로고
    • Catastrophic outcomes of noncardiac surgery soon after coronary stenting
    • Kaluza GL, Joseph J, Lee JR, et al. Catastrophic outcomes of noncardiac surgery soon after coronary stenting. J Am Coll Cardiol. 2000;35:1288-1294.
    • (2000) J Am Coll Cardiol , vol.35 , pp. 1288-1294
    • Kaluza, G.L.1    Joseph, J.2    Lee, J.R.3
  • 44
    • 0038488370 scopus 로고    scopus 로고
    • Clinical outcome of patients undergoing non-cardiac surgery in the two months following coronary stenting
    • Wilson S, Fasseas P, Orford J, et al. Clinical outcome of patients undergoing non-cardiac surgery in the two months following coronary stenting. J Am Coll Cardiol. 2003;42:234-240.
    • (2003) J Am Coll Cardiol , vol.42 , pp. 234-240
    • Wilson, S.1    Fasseas, P.2    Orford, J.3
  • 45
    • 0037030658 scopus 로고    scopus 로고
    • A randomized comparison of a sirolimus-eluting stent with a standard stent for coronary revascularization
    • Morice M, Serruys P, Sousa J, et al. A randomized comparison of a sirolimus-eluting stent with a standard stent for coronary revascularization. N Engl J Med. 2002;346:1773-1780.
    • (2002) N Engl J Med , vol.346 , pp. 1773-1780
    • Morice, M.1    Serruys, P.2    Sousa, J.3
  • 46
    • 0141863201 scopus 로고    scopus 로고
    • Sirolimus-eluting stents for treatment of patients with long atherosclerotic lesions in small coronary arteries: Double-blind, randomised controlled trial (E-SIRIUS)
    • Schofer J, Schluter M, Gershlick A, et al. Sirolimus-eluting stents for treatment of patients with long atherosclerotic lesions in small coronary arteries: double-blind, randomised controlled trial (E-SIRIUS). Lancet. 2003;362:1093-1099.
    • (2003) Lancet , vol.362 , pp. 1093-1099
    • Schofer, J.1    Schluter, M.2    Gershlick, A.3
  • 47
    • 0141765805 scopus 로고    scopus 로고
    • Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coronary artery
    • Moses JW, Leon MB, Popma JJ, et al. Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coronary artery. N Engl J Med. 2003;349:1315-1323.
    • (2003) N Engl J Med , vol.349 , pp. 1315-1323
    • Moses, J.W.1    Leon, M.B.2    Popma, J.J.3
  • 48
    • 9144249927 scopus 로고    scopus 로고
    • A polymer-based, paclitaxel-eluting stent in patients with coronary artery disease
    • Stone GW, Ellis SG, Cox DA, et al. A polymer-based, paclitaxel-eluting stent in patients with coronary artery disease. N Engl J Med. 2004;350:221-231.
    • (2004) N Engl J Med , vol.350 , pp. 221-231
    • Stone, G.W.1    Ellis, S.G.2    Cox, D.A.3


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