메뉴 건너뛰기




Volumn 29, Issue 1, 2007, Pages 87-95

Concentrations of mycophenolic acid and glucuronide metabolites under concomitant therapy with cyclosporine or tacrolimus

Author keywords

Acyl MPAG; Cyclosporine; Ketoconazole; MPAG; Mycophenolic acid; Pharmacokinetics; Tacrolimus

Indexed keywords

ATORVASTATIN; CYCLOSPORIN; GLUCURONIDE; KETOCONAZOLE; MYCOPHENOLIC ACID; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; MYCOPHENOLIC ACID ACYL GLUCURONIDE; MYCOPHENOLIC ACID PHENYL GLUCURONIDE; PRAVASTATIN; PREDNISONE; TACROLIMUS; UNCLASSIFIED DRUG;

EID: 33847137376     PISSN: 01634356     EISSN: None     Source Type: Journal    
DOI: 10.1097/FTD.0b013e3180318c35     Document Type: Article
Times cited : (19)

References (26)
  • 1
    • 10844292763 scopus 로고    scopus 로고
    • Immunosuppressive drugs for kidney transplantation
    • Halloran PF. Immunosuppressive drugs for kidney transplantation. N Engl J Med. 2004;351:2715-2729.
    • (2004) N Engl J Med , vol.351 , pp. 2715-2729
    • Halloran, P.F.1
  • 2
    • 0029864837 scopus 로고    scopus 로고
    • pharmacokinetics and bioavailability of mycophenolate mofetil in healthy subjects after single-dose oral and intravenous administration
    • Bullingham R, Monroe S, Nicholls A, et al. pharmacokinetics and bioavailability of mycophenolate mofetil in healthy subjects after single-dose oral and intravenous administration. J Clin Pharmacol. 1996;36:315-324.
    • (1996) J Clin Pharmacol , vol.36 , pp. 315-324
    • Bullingham, R.1    Monroe, S.2    Nicholls, A.3
  • 3
    • 11144318750 scopus 로고    scopus 로고
    • Identification of the UDP-glucuronosyltransferase isoforms involved in mycophenolic Acid phase II metabolism
    • Picard N, Ratanasavanh D, Premaud A, et al. Identification of the UDP-glucuronosyltransferase isoforms involved in mycophenolic Acid phase II metabolism. Drug Metab Dispos. 2005;33:139-146.
    • (2005) Drug Metab Dispos , vol.33 , pp. 139-146
    • Picard, N.1    Ratanasavanh, D.2    Premaud, A.3
  • 4
    • 0035079669 scopus 로고    scopus 로고
    • Glucuronide and glucoside conjugation of mycophenolic acid by human liver, kidney and intestinal microsomes
    • Shipkova M, Strassburg CP, Braun F, et al. Glucuronide and glucoside conjugation of mycophenolic acid by human liver, kidney and intestinal microsomes. Br J Pharmacol. 2001;132:1027-1034.
    • (2001) Br J Pharmacol , vol.132 , pp. 1027-1034
    • Shipkova, M.1    Strassburg, C.P.2    Braun, F.3
  • 5
    • 0037306174 scopus 로고    scopus 로고
    • Acyl glucuronide drug metabolites: Toxicological and analytical implications
    • Shipkova M, Armstrong VW, Oellerich M, et al. Acyl glucuronide drug metabolites: toxicological and analytical implications. Ther Drug Monit. 2003;25:1-16.
    • (2003) Ther Drug Monit , vol.25 , pp. 1-16
    • Shipkova, M.1    Armstrong, V.W.2    Oellerich, M.3
  • 6
    • 0038246498 scopus 로고    scopus 로고
    • Mycophenolic acid pharmacodynamics and pharmacokinetics provide a basis for rational monitoring strategies
    • Shaw LM, Korecka M, Venkataramanan R, et al. Mycophenolic acid pharmacodynamics and pharmacokinetics provide a basis for rational monitoring strategies. Am J Transplant. 2003;3:534-542.
    • (2003) Am J Transplant , vol.3 , pp. 534-542
    • Shaw, L.M.1    Korecka, M.2    Venkataramanan, R.3
  • 7
    • 33745957413 scopus 로고    scopus 로고
    • Therapeutic drug monitoring of mycophenolate mofetil in transplantation
    • van GT, Meur YL, Shaw LM, et al. Therapeutic drug monitoring of mycophenolate mofetil in transplantation. Ther Drug Monit. 2006;28:145-154.
    • (2006) Ther Drug Monit , vol.28 , pp. 145-154
    • van, G.T.1    Meur, Y.L.2    Shaw, L.M.3
  • 8
    • 0030670814 scopus 로고    scopus 로고
    • Unexpected augmentation of mycophenolic acid pharmacokinetics in renal transplant patients receiving tacrolimus and mycophenolate mofetil in combination therapy, and analogous in vitro findings
    • Zucker K, Rosen A, Tsaroucha A, et al. Unexpected augmentation of mycophenolic acid pharmacokinetics in renal transplant patients receiving tacrolimus and mycophenolate mofetil in combination therapy, and analogous in vitro findings. Transpl Immunol. 1997;5:225-232.
    • (1997) Transpl Immunol , vol.5 , pp. 225-232
    • Zucker, K.1    Rosen, A.2    Tsaroucha, A.3
  • 9
    • 0033023263 scopus 로고    scopus 로고
    • Evidence that tacrolimus augments the bioavailability of mycophenolate mofetil through the inhibition of mycophenolic acid glucuronidation
    • Zucker K, Tsaroucha A, Olson L, et al. Evidence that tacrolimus augments the bioavailability of mycophenolate mofetil through the inhibition of mycophenolic acid glucuronidation. Ther Drug Monit. 1999;21:35-43.
    • (1999) Ther Drug Monit , vol.21 , pp. 35-43
    • Zucker, K.1    Tsaroucha, A.2    Olson, L.3
  • 10
    • 32044439130 scopus 로고    scopus 로고
    • Effects of calcineurin inhibitors on pharmacokinetics of mycophenolic acid and its glucuronide metabolite during the maintenance period following renal transplantation
    • Naito T, Shinno K, Maeda T, et al. Effects of calcineurin inhibitors on pharmacokinetics of mycophenolic acid and its glucuronide metabolite during the maintenance period following renal transplantation. Biol Pharm Bull. 2006;29:275-280.
    • (2006) Biol Pharm Bull , vol.29 , pp. 275-280
    • Naito, T.1    Shinno, K.2    Maeda, T.3
  • 11
    • 2442716361 scopus 로고    scopus 로고
    • Cyclosporin A, but not tacrolimus, inhibits the biliary excretion of mycophenolic acid glucuronide possibly mediated by Mrp2 in rats
    • Kobayashi M, Saitoh H, Kobayashi M, et al. Cyclosporin A, but not tacrolimus, inhibits the biliary excretion of mycophenolic acid glucuronide possibly mediated by Mrp2 in rats. J Pharmacol Exp Ther. 2004;309:1029-1035.
    • (2004) J Pharmacol Exp Ther , vol.309 , pp. 1029-1035
    • Kobayashi, M.1    Saitoh, H.2    Kobayashi, M.3
  • 12
    • 17644377916 scopus 로고    scopus 로고
    • Cyclosporine interacts with mycophenolic acid by inhibiting the multidrug resistance-associated protein 2
    • Hesselink DA, van Hest RM, Mathot RA, et al. Cyclosporine interacts with mycophenolic acid by inhibiting the multidrug resistance-associated protein 2. Am J Transplant. 2005;5:987-994.
    • (2005) Am J Transplant , vol.5 , pp. 987-994
    • Hesselink, D.A.1    van Hest, R.M.2    Mathot, R.A.3
  • 13
    • 0344286009 scopus 로고    scopus 로고
    • Effect of cyclosporine on mycophenolic acid trough levels in kidney transplant recipients
    • Gregoor PJ, de Sevaux RG, Hene RJ, et al. Effect of cyclosporine on mycophenolic acid trough levels in kidney transplant recipients. Transplantation. 1999;68:1603-1606.
    • (1999) Transplantation , vol.68 , pp. 1603-1606
    • Gregoor, P.J.1    de Sevaux, R.G.2    Hene, R.J.3
  • 14
    • 0034810009 scopus 로고    scopus 로고
    • In vivo higher glucuronidation of mycophenolic acid in male than in female recipients of a cadaveric kidney allograft and under immunosuppressive therapy with mycophenolate mofetil
    • Morissette P, Albert C, Busque S, et al. In vivo higher glucuronidation of mycophenolic acid in male than in female recipients of a cadaveric kidney allograft and under immunosuppressive therapy with mycophenolate mofetil. Ther Drug Monit. 2001;23:520-525.
    • (2001) Ther Drug Monit , vol.23 , pp. 520-525
    • Morissette, P.1    Albert, C.2    Busque, S.3
  • 15
    • 0035086852 scopus 로고    scopus 로고
    • Comparison of the effects of tacrolimus and cyclosporine on the pharmacokinetics of mycophenolic acid
    • van Gelder T, Klupp J, Barten MJ, et al. Comparison of the effects of tacrolimus and cyclosporine on the pharmacokinetics of mycophenolic acid. Ther Drug Monit. 2001;23:119-128.
    • (2001) Ther Drug Monit , vol.23 , pp. 119-128
    • van Gelder, T.1    Klupp, J.2    Barten, M.J.3
  • 16
    • 15244342623 scopus 로고    scopus 로고
    • Mycophenolic acid pharmacokinetics and related outcomes early after renal transplant
    • Atcheson BA, Taylor PJ, Mudge DW, et al. Mycophenolic acid pharmacokinetics and related outcomes early after renal transplant. Br J Clin Pharmacol. 2005;59:271-280.
    • (2005) Br J Clin Pharmacol , vol.59 , pp. 271-280
    • Atcheson, B.A.1    Taylor, P.J.2    Mudge, D.W.3
  • 17
    • 33745491120 scopus 로고    scopus 로고
    • Pharmacokinetics of mycophenolic acid and metabolites in diabetic kidney transplant recipients
    • Akhlaghi F, Patel CG, Zuniga XP, et al. Pharmacokinetics of mycophenolic acid and metabolites in diabetic kidney transplant recipients. Ther Drug Monit. 2006;28:95-101.
    • (2006) Ther Drug Monit , vol.28 , pp. 95-101
    • Akhlaghi, F.1    Patel, C.G.2    Zuniga, X.P.3
  • 18
    • 0026096515 scopus 로고
    • Cyclosporine dose reduction by ketoconazole administration in renal transplant recipients
    • First MR, Schroeder TJ, Alexander JW, et al. Cyclosporine dose reduction by ketoconazole administration in renal transplant recipients. Transplantation. 1991;51:365-370.
    • (1991) Transplantation , vol.51 , pp. 365-370
    • First, M.R.1    Schroeder, T.J.2    Alexander, J.W.3
  • 19
    • 33745497852 scopus 로고    scopus 로고
    • High-performance liquid chromatography method for the determination of mycophenolic acid and its acyl and phenol glucuronide metabolites in human plasma
    • Patel CG, Akhlaghi F. High-performance liquid chromatography method for the determination of mycophenolic acid and its acyl and phenol glucuronide metabolites in human plasma. Ther Drug Monit. 2006;28:116-122.
    • (2006) Ther Drug Monit , vol.28 , pp. 116-122
    • Patel, C.G.1    Akhlaghi, F.2
  • 20
    • 8844222031 scopus 로고    scopus 로고
    • Determination of total mycophenolic acid and its glucuronide metabolite using liquid chromatography with ultraviolet detection and unbound mycophenolic acid using tandem mass spectrometry
    • Patel CG, Mendonza AE, Akhlaghi F, et al. Determination of total mycophenolic acid and its glucuronide metabolite using liquid chromatography with ultraviolet detection and unbound mycophenolic acid using tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2004;813:287-294.
    • (2004) J Chromatogr B Analyt Technol Biomed Life Sci , vol.813 , pp. 287-294
    • Patel, C.G.1    Mendonza, A.E.2    Akhlaghi, F.3
  • 21
    • 0029089702 scopus 로고
    • Ketoconazole to reduce the need for cyclosporine after cardiac transplantation
    • Keogh A, Spratt P, McCosker C, et al. Ketoconazole to reduce the need for cyclosporine after cardiac transplantation. N Engl J Med. 1995;333:628-633.
    • (1995) N Engl J Med , vol.333 , pp. 628-633
    • Keogh, A.1    Spratt, P.2    McCosker, C.3
  • 22
    • 9644289307 scopus 로고    scopus 로고
    • Characterization of a phase 1 metabolite of mycophenolic acid produced by CYP3A4/5
    • Picard N, Cresteil T, Premaud A, et al. Characterization of a phase 1 metabolite of mycophenolic acid produced by CYP3A4/5. Ther Drug Monit. 2004;26:600-608.
    • (2004) Ther Drug Monit , vol.26 , pp. 600-608
    • Picard, N.1    Cresteil, T.2    Premaud, A.3
  • 23
    • 24944515352 scopus 로고    scopus 로고
    • An investigation of human and rat liver microsomal mycophenolic acid glucuronidation: Evidence for a principal role of UGT1A enzymes and species differences in UGT1A specificity
    • Miles KK, Stern ST, Smith PC, et al. An investigation of human and rat liver microsomal mycophenolic acid glucuronidation: evidence for a principal role of UGT1A enzymes and species differences in UGT1A specificity. Drug Metab Dispos. 2005;33:1513-1520.
    • (2005) Drug Metab Dispos , vol.33 , pp. 1513-1520
    • Miles, K.K.1    Stern, S.T.2    Smith, P.C.3
  • 24
    • 19444367783 scopus 로고    scopus 로고
    • In vivo effects of cyclosporin A and ketoconazole on the pharmacokinetics of representative substrates for P-glycoprotein and cytochrome P450 (CYP) 3A in rats
    • Kageyama M, Namiki H, Fukushima H, et al. In vivo effects of cyclosporin A and ketoconazole on the pharmacokinetics of representative substrates for P-glycoprotein and cytochrome P450 (CYP) 3A in rats. Biol Pharm Bull. 2005;28:316-322.
    • (2005) Biol Pharm Bull , vol.28 , pp. 316-322
    • Kageyama, M.1    Namiki, H.2    Fukushima, H.3
  • 25
    • 4444369519 scopus 로고    scopus 로고
    • Identification of protein targets for mycophenolic acid acyl glucuronide in rat liver and colon tissue
    • Shipkova M, Beck H, Voland A, et al. Identification of protein targets for mycophenolic acid acyl glucuronide in rat liver and colon tissue. Proteomics. 2004;4:2728-2738.
    • (2004) Proteomics , vol.4 , pp. 2728-2738
    • Shipkova, M.1    Beck, H.2    Voland, A.3
  • 26
    • 22244431879 scopus 로고    scopus 로고
    • Randomized calcineurin inhibitor cross over study to measure the pharmacokinetics of coadministered enteric-coated mycophenolate sodium
    • Kaplan B, Meier-Kriesche HU, Minnick P, et al. Randomized calcineurin inhibitor cross over study to measure the pharmacokinetics of coadministered enteric-coated mycophenolate sodium. Clin Transplant. 2005;19:551-558.
    • (2005) Clin Transplant , vol.19 , pp. 551-558
    • Kaplan, B.1    Meier-Kriesche, H.U.2    Minnick, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.