Immunohistochemical study of p53 and angiogenesis in benign and preneoplastic oral lesions and oral squamous cell carcinoma

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology

Volumn 103, Issue 3, 2007, Pages 385-390

  Abbas, Naglaa Fathy ^a   Labib El Sharkawy, Sonia ^a   Abbas, Effat Ahmed ^a   Abdel Monem El Shaer, Marwa ^a  

^a Department of Pathology ^*  (Egypt)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53; TUMOR MARKER; VON WILLEBRAND FACTOR;

ANALYSIS OF VARIANCE; ARTICLE; CELL TRANSFORMATION; CHEMISTRY; GENE EXPRESSION REGULATION; HUMAN; IMMUNOHISTOCHEMISTRY; MOUTH MUCOSA; MOUTH TUMOR; MUTATION; NEOVASCULARIZATION (PATHOLOGY); NONPARAMETRIC TEST; PATHOLOGY; PRECANCER; PROGNOSIS; SQUAMOUS CELL CARCINOMA;

ANALYSIS OF VARIANCE; CARCINOMA, SQUAMOUS CELL; CELL TRANSFORMATION, NEOPLASTIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; MOUTH MUCOSA; MOUTH NEOPLASMS; MUTATION; NEOVASCULARIZATION, PATHOLOGIC; PRECANCEROUS CONDITIONS; PROGNOSIS; STATISTICS, NONPARAMETRIC; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEIN P53; VON WILLEBRAND FACTOR;

EID: 33847102635     PISSN: 10792104     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tripleo.2005.11.008     Document Type: Article

References (28)

1. Tandle A.T., Sanghvi V., and Saranath D. Determination of p53 genotypes in oral cancer patients from India. Br J Cancer 84 (2001) 739-742
2. Carlos de Vicente J., Junquera Gutierrez L.M., Zapatero A.H., Fresno Forcelledo M.F., Hernandez-Vallejo G., and Lopez Arranz J.S. Prognostic significance of p53 expression in oral squamous cell carcinoma without neck node metastases. Head Neck 26 (2004) 22-30
3. Cotran R.S., Kumar V., and Collins T.R. Robbins pathologic basis of diseases. 6th ed. (1999), Saunders, Philadelphia 290-292
4. Levine A.J. p53, the cellular gatekeeper for growth and division. Cell 88 (1997) 323-331
5. Hussain S.P., and Harris C.C. Molecular epidemiology of human cancer: contribution of mutation spectra studies of tumor suppressor genes. Cancer Res 58 (1998) 4023-4037
6. Nakopoulou L., Vourlakou C., Zervas A., Tzonou A., Gakiopoulou H., and Dimopoulos M.A. The prevalence of bcl-2, p53, and Ki-67 immunoreactivity in transitional cell bladder carcinomas and their clinicopathologic correlates. Hum Pathol 29 (1998) 146-154
7. Ravi D., Ramadas K., Mathew B.S., Nalinakumari K.R., Nair M.K., and Pillai M.R. Angiogenesis during tumor progression in the oral cavity is related to reduced apoptosis and high tumor cell proliferation. Oral Oncol 34 (1998) 543-548
8. Schimming R., Reusch P., Kuschnierz J., and Schmelzeisen R. Angiogenic factors in squamous cell carcinoma of the oral cavity: do they have prognostic relevance?. J Craniomaxillofac Surg 32 (2004) 176-181
9. Forootan S.S., Jones A.S., and Helliwell T.R. Neoangiogenesis and squamous cell carcinoma of the tongue. Cancer Detect Prev 23 (1999) 137-146
10. Shieh Y.S., Lee H.S., Shiah S.G., Chu Y.W., Wu C.W., and Chang L.C. Role of angiogenic and non-angiogenic mechanisms in oral squamous cell carcinoma: correlation with histologic differentiation and tumor progression. J Oral Pathol Med 33 (2004) 601-606
11. Penfold C.N., Partridge M., Rojas R., and Langdon J.D. The role of angiogenesis in the spread of oral squamous cell carcinoma. Br J Oral Maxillofac Surg 34 (1996) 37-41
12. Hanahan D., and Folkman J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 86 (1996) 353-364
13. Grossfeld G.D., Ginsberg D.A., Stein J.P., Bochner B.H., Esrig D., Groshen S., et al. Thrombospondin-1 expression in bladder cancer: association with p53 alterations, tumor angiogenesis, and tumor progression. J Natl Cancer Inst 89 (1997) 219-227
14. Elpek G.O., Gelen T., Aksoy N.H., Erdogan A., Dertsiz L., Demircan A., et al. The prognostic relevance of angiogenesis and mast cells in squamous cell carcinoma of the oesophagus. J Clin Pathol 54 (2001) 940-944
15. Macluskey M., Chandrachud L.M., Pazouki S., Green M., Chisholm D.M., Ogden G.R., et al. Apoptosis, proliferation, and angiogenesis in oral tissues. Possible relevance to tumor progression. J Pathol 191 (2000) 368-375
16. Pindborg J.J., Reichart P.A., Smith C.J., and World Health Organization. International typing of cancer and precancer of the oral mucosa. 2nd ed. (1997), Springer-Verlag, Berlin Heidelberg
17. Lee A.H., Dublin E.A., Bobrow L.G., and Poulsom R. Invasive lobular and invasive ductal carcinoma of the breast show distinct patterns of vascular endothelial growth factor expression and angiogenesis. J Pathol 185 (1998) 394-401
18. van Oijen M.G., van de Craats J.G., and Slootweg P.J. p53 overexpression in oral mucosa in relation to smoking. J Pathol 187 (1999) 469-474
19. Hogmo A., Kuylenstierna R., Lindholm J., and Munck-Wikland E. Predictive value of malignancy grading systems, DNA content, p53, and angiogenesis for stage I tongue carcinomas. J Clin Pathol 52 (1999) 35-40
20. Cruz I.B., Snijders P.J., Meijer C.J., Braakhuis B.J., Snow G.B., Walboomers J.M., et al. p53 expression above the basal cell layer in oral mucosa is an early event of malignant transformation and has predictive value for developing oral squamous cell carcinoma. J Pathol 184 (1998) 360-368
21. Piattelli A., Rubini C., Fioroni M., Iezzi G., and Santinelli A. Prevalence of p53, bcl-2, and Ki-67 immunoreactivity and of apoptosis in normal oral epithelium and in premalignant and malignant lesions of the oral cavity. J Oral Maxillofac Surg 60 (2002) 532-540
22. Iamaroon A., Khemaleelakul U., Pongsiriwet S., and Pintong J. Co-expression of p53 and Ki67 and lack of EBV expression in oral squamous cell carcinoma. J Oral Pathol Med 33 (2004) 30-36
23. Slootweg P.J., Koole R., and Hordijk G.J. The presence of p53 protein in relation to Ki-67 as cellular proliferation marker in head and neck squamous cell carcinoma and adjacent dysplastic mucosa. Eur J Cancer B Oral Oncol 30B (1994) 138-141
24. Murti P.R., Warnakulasuriya K.A., Johnson N.W., Bhonsle R.B., Gupta P.C., Daftary D.K., et al. p53 expression in oral precancer as a marker for malignant potential. J Oral Pathol Med 27 (1998) 191-196
25. Girod S.C., Pfeiffer P., Ries J., and Pape H.D. Proliferative activity and loss of function of tumor suppressor genes as 'biomarkers' in diagnosis and prognosis of benign and preneoplastic oral lesions and oral squamous cell carcinoma. Br J Oral Maxillofac Surg 36 (1998) 252-260
26. Famulski W., Sulkowska M., Miller-Famulska D., Terlikowski S., Guzinska-Ustymowicz K., and Sulkowski S. P53 protein expression in oral squamous cell cancer in relation to some of its clinicopathological variables. Folia Histochem Cytobiol 40 (2002) 203-204
27. Moriyama M., Kumagai S., Kawashiri S., Kojima K., Kakihara K., and Yamamoto E. Immunohistochemical study of tumor angiogenesis in oral squamous cell carcinoma. Oral Oncol 33 (1997) 369-374
28. Pazouki S., Chisholm D.M., Adi M.M., Carmichael G., Farquharson M., Ogden G.R., et al. The association between tumor progression and vascularity in the oral mucosa. J Pathol 183 (1997) 39-43