Azithromycin-sulfonamide conjugates as inhibitors of resistant Streptococcus pyogenes strains

European Journal of Medicinal Chemistry

Volumn 42, Issue 2, 2007, Pages 138-145

  Bukvić Krajačić, Mirjana ^a   Novak, Predrag ^b,c   Cindrić, Mario ^a   Brajša, Karmen ^b   Dumić, Miljenko ^a   Kujundžić, Nedjeljko ^b  

^a PLIVA CROATIA LTD   (Croatia)

^b PLIVA Research Institute Ltd   (Croatia)

^c UNIVERSITY OF ZAGREB   (Croatia)

Author keywords

15 Membered azalides; Acid stability; Antimicrobial activity; Azithromycin sulfonamide conjugates; Structural elucidation

Indexed keywords

AZITHROMYCIN; CARBOHYDRATE DERIVATIVE; ERYTHROMYCIN DERIVATIVE; HETEROCYCLIC COMPOUND; MACROLIDE; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; SULFONAMIDE; SULFONE DERIVATIVE;

ANALYTIC METHOD; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL STRAIN; CONJUGATE; DECOMPOSITION; DEGRADATION; DRUG SCREENING; DRUG SYNTHESIS; ESCHERICHIA COLI; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HAEMOPHILUS INFLUENZAE; HYBRID; IN VITRO STUDY; INFRARED SPECTROSCOPY; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MINIMUM INHIBITORY CONCENTRATION; MORAXELLA CATARRHALIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; STAPHYLOCOCCUS AUREUS; STOMACH JUICE; STREPTOCOCCUS PNEUMONIAE; STREPTOCOCCUS PYOGENES;

ACETALDEHYDE; ANTI-BACTERIAL AGENTS; AZITHROMYCIN; DRUG RESISTANCE, BACTERIAL; DRUG STABILITY; HYDROLYSIS; MAGNETIC RESONANCE SPECTROSCOPY; SPECTROPHOTOMETRY, INFRARED; STREPTOCOCCUS PYOGENES; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONAMIDES; TANDEM MASS SPECTROMETRY;

EID: 33847097999     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2006.08.008     Document Type: Article

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